Condition

ANCA Associated Vasculitis clinical trials and research

• 19Clinical trials
• 5NIH research projects
• 5Countries

Newest ANCA Associated Vasculitis clinical trials

All recruiting trials (19)

• BCT301 CAR-iT cell therapy for hard-to-treat autoimmune diseases

  This early‑phase study tests whether off-the-shelf BCT301 CAR-iT cells can be given safely to adults with refractory autoimmune diseases to see if they can be tolerated and what dose works best.

  Recruiting Early Phase 1 Peking University Third Hospital · Beijing · NCT07301164

• Characterization of Autoreactive B Cells in Autoimmune Diseases and Immune Deficiencies

  Researchers are testing to see how autoreactive B cells behave in people with autoimmune diseases or immune deficiencies to better understand how these cells may contribute to disease.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT07251179

• Anti-CD19/BCMA universal CAR-T (RD06-05) for autoimmune diseases

  This early-phase test gives a universal CAR-T therapy (RD06-05) that targets CD19 and BCMA to adults with autoimmune diseases such as SLE/lupus nephritis, ANCA-associated vasculitis, and anti-GBM disease.

  Recruiting Early Phase 1 Nanjing Bioheng Biotech Co., Ltd. · Shanghai, Shanghai Municipality · NCT07203404

• Gallium-68 FAPI PET/CT imaging for people with ANCA-associated vasculitis

  This project will test whether Gallium-68 FAPI PET/CT scans can detect lung and kidney involvement in adults with ANCA-associated vasculitis.

  Recruiting Ruijin Hospital · Shanghai · NCT07151521

• Imaging in Inflammatory Heart Diseases linked to autoimmune disorders

  This study tests how well multimodality imaging (CMR, echocardiography, and PET) detects inflammation in people with suspected inflammatory heart or autoimmune rheumatic diseases.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT07077304

• Epithelial Dysmetabolism and Kidney Fibrosis in ANCA Vasculitis

  This study tests whether alterations in tubulo-interstitial metabolism relate to how quickly kidney function deteriorates in people with ANCA-associated vasculitis compared to other nephropathies.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT07010250

• Using avacopan for treating ANCA-associated vasculitis in real-world settings

  This study looks at how well avacopan works for treating people with ANCA-associated vasculitis in real-life situations across Europe.

  Recruiting Leiden University Medical Center · Leiden · NCT06794827

• BCMA-CD19 CAR-T therapy for autoimmune diseases

  This study is testing a new CAR-T cell therapy to see if it can help adults with tough autoimmune diseases feel better and improve their health.

  Recruiting Phase 2 Peking University People's Hospital · Beijing, Beijing Municipality · NCT06794008

• Using CAR T-cell therapy to treat severe autoimmune diseases

  This study is testing if a new CAR T-cell therapy can help people with severe autoimmune diseases like lupus and scleroderma feel better.

  Recruiting Phase 1/2 Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome, Lazio · NCT06685042

• Targeted CAR-T therapy for autoimmune diseases

  This study is testing a new type of CAR-T therapy to see if it can help people with active autoimmune diseases feel better and manage their symptoms.

  Recruiting Early Phase 1 Nanjing Bioheng Biotech Co., Ltd. · Bengbu, Anhui · NCT06548607

• Investigating Neutrophil Extracellular Traps in Systemic Sclerosis

  This study is trying to understand how certain immune cells called Neutrophil Extracellular Traps might be linked to the symptoms and complications of Systemic Sclerosis in patients.

  Recruiting CHU de Reims · Reims · NCT06462768

• FKC288 treatment for autoimmune kidney diseases

  This study is testing a new treatment called FKC288 to see if it can help people with tough autoimmune kidney diseases like lupus nephritis and ANCA-associated vasculitis.

  Recruiting Phase 1 Nanjing University School of Medicine · Nanjing, Jiangsu · NCT06285279

• CAR-T cell therapy for treating severe autoimmune diseases

  This study is testing a new CAR-T cell therapy to see if it can help people with severe autoimmune diseases like lupus nephritis and vasculitis who haven't found relief with other treatments.

  Recruiting Tongji Hospital · Wuhan, Hubei · NCT06277427

• Comparing Telitacicept with Azathioprine for ANCA-associated Vasculitis Maintenance

  This study is testing if adding a new drug called Telitacicept to the standard treatment can help people with ANCA-associated vasculitis stay in remission longer.

  Recruiting Phase 4 Chinese SLE Treatment And Research Group · Beijing, Beijing Municipality · NCT05965284

• Combining Rituximab and Telitacicept for treating ANCA-associated Vasculitis

  This study is testing if adding Telitacicept to Rituximab treatment can help people with ANCA-associated vasculitis stay in remission longer.

  Recruiting Phase 4 Chinese SLE Treatment And Research Group · Beijing · NCT05962840

• Evaluating Pioglitazone for Kidney Health in ANCA-associated Vasculitis

  This study is testing if adding pioglitazone to standard treatment can help improve kidney health in people with ANCA-associated vasculitis.

  Recruiting at 24 sites Phase 3 Assistance Publique - Hôpitaux de Paris · Amiens and 24 other locations · NCT05946564

• Collection of data from patients with ANCA-associated vasculitis

  This study is collecting information and samples from people with ANCA-associated vasculitis to see if they can find out who is more likely to have a relapse and who might be able to stop their medications safely.

  Recruiting University Hospital, Brest · Brest, Brest · NCT05364892

• Observational study on ANCA-associated vasculitis in Hunan, China

  This study is looking at how common ANCA-associated vasculitis is and how it affects about 500 patients in Hunan, China, over five years to see if it leads to serious kidney problems or death.

  Recruiting Xiangya Hospital of Central South University · Changsha, Hunan · NCT05315141

• Understanding the natural history and outcomes of systemic vasculitis

  This study is trying to understand how systemic vasculitis affects people over time and what signs can help predict how the disease will progress, involving both patients with vasculitis and healthy volunteers.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT02257866

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Molecular and clinical clues to relapse in ANCA-related vasculitis

  Researchers are studying nasal and airway signals, including bacteria and gene activity, to find predictors that a person with ANCA-associated vasculitis might relapse.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11361068

• Virtual Mind-Body Resiliency for SARDs (AAV and SLE)

  A patient-facing program will test a virtual group-based mind-body approach to help people with ANCA-associated vasculitis and lupus cope with stress and improve well-being.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11357846

• Understanding ANCA-Associated Vasculitis Relapse from Upper Airway Changes

  This project aims to find early signs in the nose that can tell us when ANCA-associated vasculitis (AAV) might come back, helping doctors better manage the disease.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11141014

• Investigating predictors of relapse in ANCA-associated vasculitis

  This study is looking at how certain genes and bacteria in the nose can help predict when people with ANCA-associated vasculitis might have a relapse, even if they aren't showing any symptoms, so doctors can better adjust their treatments and manage the condition.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-10945401

• Exploring the role of a protein in a type of blood vessel inflammation

  This study is looking at how a protein called alpha-1 antitrypsin influences immune cells in people with ANCA-associated vasculitis, a rare autoimmune disease, to help find better ways to treat and predict flare-ups for those affected.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-10887261

Related topics

Quick answers

How many ANCA Associated Vasculitis clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in China (10 trials), France (6 trials), Italy (1 trial), Netherlands (1 trial), United States (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 3, Phase 4: 2, Phase 2: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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