Condition

Sjogren Syndrome clinical trials and research

• 8Clinical trials
• 13Countries

Newest Sjogren Syndrome clinical trials

All recruiting trials (8)

• BCT301 CAR-iT cell therapy for hard-to-treat autoimmune diseases

  This early‑phase study tests whether off-the-shelf BCT301 CAR-iT cells can be given safely to adults with refractory autoimmune diseases to see if they can be tolerated and what dose works best.

  Recruiting Early Phase 1 Peking University Third Hospital · Beijing · NCT07301164

• Interferon patterns in cancer patients receiving CTLA-4 or PD-1/PD-L1 inhibitors versus autoimmune disease

  This project will test whether blood interferon levels can help predict immune-related side effects in adults starting checkpoint inhibitor immunotherapy by comparing them with people who have autoimmune diseases.

  Recruiting Hospital Universitario Araba · Pamplona, Navarre · NCT07249060

• Vaginal fractional CO2 laser versus topical promestriene for vaginal dryness in Sjögren's disease

  This trial will test whether monthly vaginal fractional CO2 laser or ongoing topical promestriene helps women with Sjögren's disease who have vaginal dryness.

  Recruiting Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07153276

• AlloNK® therapy combined with rituximab for treating certain autoimmune diseases

  This study is testing if a new treatment called AlloNK® combined with rituximab can help people with tough-to-treat autoimmune diseases feel better.

  Recruiting at 52 sites Phase 2 Artiva Biotherapeutics, Inc. · Tuscaloosa, Alabama and 51 other locations · NCT06991114

• Three approaches to reduce fatigue in Sjögren's syndrome

  This trial will try adapted physical activity alone, adapted physical activity plus acupuncture, and adapted physical activity plus transcutaneous vagal nerve stimulation to see if they reduce chronic fatigue in adults with Sjögren's syndrome.

  Recruiting Centre Hospitalier Universitaire de Saint Etienne · Saint-Etienne · NCT06875102

• Universal CD19-targeting CAR-γδT cell therapy for refractory autoimmune diseases

  This trial will try infusing universal CD19-targeting CAR-γδT cells into adults with refractory B cell–driven autoimmune diseases to see if removing autoreactive B cells improves symptoms.

  Recruiting Phase 1/2 Peking University Third Hospital · Beijing · NCT06828042

• BCMA-CD19 CAR-T therapy for autoimmune diseases

  This study is testing a new CAR-T cell therapy to see if it can help adults with tough autoimmune diseases feel better and improve their health.

  Recruiting Phase 2 Peking University People's Hospital · Beijing, Beijing Municipality · NCT06794008

• Using nivolumab to treat patients with autoimmune disorders and advanced cancer

  This study is testing if nivolumab can safely help people with autoimmune disorders who also have advanced cancer by looking at how well it works and what side effects it might cause.

  Recruiting at 40 sites Phase 1 National Cancer Institute (NCI) · Birmingham, Alabama and 51 other locations · NCT03816345

Related topics

Quick answers

How many Sjogren Syndrome clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in China (3 trials), Spain (2 trials), France (2 trials), United States (2 trials), Brazil (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Early Phase 1: 1, Phase 1/2: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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