Observational study on ANCA-associated vasculitis in Hunan, China
Official title: Multicenter Cohort Study of ANCA-associated Small Vasculitis in Hunan Province of China
Run by Xiangya Hospital of Central South University · NCT05315141 · Data updated 2026-11-12
This study is looking at how common ANCA-associated vasculitis is and how it affects about 500 patients in Hunan, China, over five years to see if it leads to serious kidney problems or death.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Xiangya Hospital of Central South University Academic / other |
| Locations | 1 site (Changsha, Hunan) |
| Status | Recruiting |
| Started | March 16, 2022 |
| Main results expected | March 16, 2027 |
| Study ends | March 16, 2027 |
| Registry record updated | April 7, 2022 |
| Trial ID | NCT05315141 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals who meet the 2012 criteria for ANCA-associated vasculitis and are willing to provide informed consent.
✕Probably not a fit
Patients who do not meet the criteria for ANCA-associated vasculitis or refuse to sign informed consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This multicenter cohort study aims to investigate the incidence and progression of Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) among approximately 500 patients in Hunan province, China. Participants will be followed for at least 5 years, during which demographic, clinical, and laboratory data will be collected at baseline and annually. The study focuses on key outcomes such as end-stage renal disease (ESRD) and mortality, with detailed assessments conducted at each follow-up visit. The goal is to understand the relationship between AAV progression and adverse health outcomes.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the progression of ANCA-associated vasculitis and its impact on patient outcomes, potentially leading to improved management strategies.
How similar studies have gone: While there have been studies on ANCA-associated vasculitis, this specific multicenter cohort approach focusing on long-term outcomes in this region is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Fulfill 2012 criteria of ANCA associated vasculitis and agree to sign informed consent Exclusion Criteria: * Do not agree to sign informed consent
Where it's running
-
Xiangya hospital
Changsha, Hunan, China Recruiting
Study contacts
- Principal investigator: Xiangcheng Xiao, doctor — Xiangya Hospital of Central South University
- Study coordinator: Yong Zhong, doctor
- Email: zhongyong121@163.com
- Phone: +86073189753025
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.