Observational study on ANCA-associated vasculitis in Hunan, China
Multicenter Cohort Study of ANCA-associated Small Vasculitis in Hunan Province of China
This study is looking at how common ANCA-associated vasculitis is and how it affects about 500 patients in Hunan, China, over five years to see if it leads to serious kidney problems or death.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Sex | All |
| Sponsor | Xiangya Hospital of Central South University Academic / other |
| Locations | 1 site (Changsha, Hunan) |
| Trial ID | NCT05315141 on ClinicalTrials.gov |
What this trial studies
This multicenter cohort study aims to investigate the incidence and progression of Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) among approximately 500 patients in Hunan province, China. Participants will be followed for at least 5 years, during which demographic, clinical, and laboratory data will be collected at baseline and annually. The study focuses on key outcomes such as end-stage renal disease (ESRD) and mortality, with detailed assessments conducted at each follow-up visit. The goal is to understand the relationship between AAV progression and adverse health outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals who meet the 2012 criteria for ANCA-associated vasculitis and are willing to provide informed consent.
Not a fit: Patients who do not meet the criteria for ANCA-associated vasculitis or refuse to sign informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the progression of ANCA-associated vasculitis and its impact on patient outcomes, potentially leading to improved management strategies.
How similar studies have performed: While there have been studies on ANCA-associated vasculitis, this specific multicenter cohort approach focusing on long-term outcomes in this region is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Fulfill 2012 criteria of ANCA associated vasculitis and agree to sign informed consent Exclusion Criteria: * Do not agree to sign informed consent
Where this trial is running
Changsha, Hunan
- Xiangya hospital — Changsha, Hunan, China (Recruiting)
Study contacts
- Principal investigator: Xiangcheng Xiao, doctor — Xiangya Hospital of Central South University
- Study coordinator: Yong Zhong, doctor
- Email: zhongyong121@163.com
- Phone: +86073189753025
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.