Sponsor or institution
Clinical trials and research at Wake Forest University
As of November 12, 2026, Find a Trial lists 3 clinical trials run by Wake Forest University that are recruiting, in United States. By phase: Phase 2 (1). There are also 29 NIH-funded research projects at this institution, with $22.5 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 29NIH research projects
- 1Country
Newest trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Mobile program to reduce pain and improve health in older adults with osteoarthritis | Phase 2 | Winston-Salem, North Carolina | Recruiting | Oct 2, 2024 |
| Testing beet-root juice and red light therapy for muscle endurance in older adults | — | Winston-Salem, North Carolina | Recruiting | Oct 27, 2022 |
| Using virtual reality to promote physical activity and social connection in adults | — | Winston-Salem, North Carolina | Recruiting | Feb 16, 2021 |
All recruiting trials (3)
-
Mobile program to reduce pain and improve health in older adults with osteoarthritis
This trial tests a mobile group-based program combining frequent movement and dietary changes to help older adults with obesity and knee or hip osteoarthritis lose weight, move more, and reduce pain.
-
Testing beet-root juice and red light therapy for muscle endurance in older adults
This study is testing whether beet-root juice and red light therapy can help older adults improve their muscle endurance.
-
Using virtual reality to promote physical activity and social connection in adults
This study is testing whether using virtual reality can help adults aged 45-80 who are not very active to get moving and connect with others while exercising from home.
NIH-funded research (29)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
-
Overcoming glutamate-driven brain damage during metabolic stress
A researcher at Wake Forest University is studying how the brain can avoid damaging glutamate surges during metabolic stress, with potential relevance to Alzheimer’s and other neurodegenerative diseases.
-
How social experiences shape brain circuits for recognizing others
This work will learn how social experiences change the brain circuits that help adults recognize and respond to other people.
-
Neuroimaging and multi-omics to subtype Alzheimer's and predict its course with confidence
A project at Wake Forest University aims to combine brain scans with genetic, RNA, and protein data to identify distinct Alzheimer's subtypes and predict how the disease will progress with reliable uncertainty estimates.
-
Chemical biology of nitroxyl (HNO) in Bacillus subtilis and its link to bacterial redox health
This grant explores how nitroxyl (HNO) interacts with bacterial redox chemistry to understand potential new ways to combat anthrax-causing bacteria.
-
Mobile health program to reduce pain and boost function in older adults with knee/hip osteoarthritis
A remotely delivered program helps adults 65+ who have knee or hip osteoarthritis reduce pain and improve daily function by promoting more activity and better weight management.
-
Exercise and bone-strengthening medication to protect bones during weight loss in older adults
A year-long study will test whether resistance training, bone-loading exercise, and a common osteoporosis drug can help older adults lose weight without losing bone density.
-
Osteoarthritis Prevention in Women: Weight Loss and Exercise to Keep Knees Healthy
A big study is testing whether a combined plan of weight loss, exercise, and staying with the plan can prevent knee arthritis in women aged 50 and older who are overweight.
-
Biomedical Uses of Reactive Sulfur and Selenium in Diagnosis and Care
This research explores how reactive sulfur and selenium compounds could help diagnose and treat diseases like Alzheimer’s and cancer in people.
-
Muscle power as a predictor of knee arthritis risk in at-risk women
A study to see if how strong your knee muscles are can predict future knee arthritis in women who are at higher risk.
-
How rotavirus copies its genetic material and builds new virus particles
Learning how the rotavirus enzyme copies viral RNA to help protect infants and young children from severe diarrhea.
-
Monthly risedronate pill to protect bones after sleeve gastrectomy
This will see if a once-monthly risedronate pill helps protect bone health for people who have had sleeve gastrectomy.
-
New approach to severe malaria-related anemia using the body’s antioxidant balance
This project explores whether boosting a key antioxidant in red blood cells can help prevent or reduce severe anemia in people with malaria.
-
Remote weight-loss and daily-movement program to ease pain for older adults
A remote group program combining modest calorie reduction and frequent walking to help older adults with knee or hip osteoarthritis and obesity walk more and lessen how much pain disrupts their daily life.
-
Resistance exercise plus osteoporosis medication to protect bones during weight loss in older adults
This project looks at whether strength-focused exercise combined with a common osteoporosis drug helps older adults keep bone density while losing weight.
-
Preventing knee osteoarthritis in older women
Looks at whether a program of diet-based weight loss, exercise, and long-term weight-maintenance can prevent knee osteoarthritis in women aged 50 and older with obesity and little or no knee pain.
-
Investigating how muscle power affects knee osteoarthritis in at-risk women
This study is looking at how strong your knee muscles are and how that might help predict knee osteoarthritis in women who are at risk, so we can find ways to prevent it and improve mobility and pain levels.
-
Exploring the use of reactive sulfur and selenium compounds for diagnosing and treating diseases.
This study is looking at how certain natural compounds, called reactive sulfur and selenium species, can help improve health and treat diseases like cancer, Alzheimer's, and heart problems, with the goal of finding better ways to deliver and detect these compounds for patients.
-
Exploring the effects of nitroxyl in a type of bacteria.
This study is looking at how a special chemical called nitroxyl interacts with a common bacteria, Bacillus subtilis, to see if it can help fight off antibiotic-resistant infections, which could lead to better treatments for patients in the future.
-
Understanding ribosomal proteins' role in Diamond-Blackfan anemia
This study is looking at how certain proteins in our cells might be linked to Diamond-Blackfan anemia, a condition that makes it hard for the body to produce enough red blood cells, and it hopes to find new ways to help people with this condition by using a simple organism to learn more about these proteins.
-
Understanding how rotavirus replicates and assembles its genome
This study is looking at how the rotavirus, which causes bad diarrhea in little kids, makes copies of itself and puts its parts together, with the hope of finding new ways to create medicines that can help fight off this virus.
-
A mobile program to help older adults manage pain and improve health.
This study is designed for older adults with knee or hip pain from osteoarthritis, and it aims to help them feel better by encouraging more movement and healthier eating habits over six months, all while providing support in a friendly group setting.
-
Using exercise and medication to prevent bone loss during weight loss in older adults
This study is looking at how combining exercise with a medication called bisphosphonate can help older adults who are losing weight keep their bones strong and healthy over a year-long program.
-
Preventing knee osteoarthritis in adult women through weight loss and exercise
This study is looking for women over 50 who are overweight and have little to no knee pain to try a program that combines healthy eating and exercise to see if it can help prevent knee osteoarthritis.
-
Finding bacteria to create a probiotic that boosts nitric oxide levels in the body
This study is looking at how some good bacteria in your mouth can help turn the food you eat into important substances that your body needs, and it aims to create a probiotic that could help people with conditions like anemia and heart failure by boosting these helpful bacteria.
-
Using bisphosphonates to prevent bone loss after weight loss surgery
This study is looking at whether a monthly medication called risedronate can help people who have had sleeve gastrectomy surgery keep their bones strong and reduce the risk of fractures as they lose weight.
-
Understanding how oxygen levels affect malaria parasite growth
This study looks at how different levels of oxygen in the body affect the growth of malaria parasites, which could help us understand why some treatments don’t work and lead to better ways to fight malaria, especially in tough cases.
-
Investigating the role of nitroxyl in bacteria related to anthrax
This study is looking at how some bacteria, like those that cause anthrax, use sulfur to grow and survive, and it hopes to find new ways to create antibiotics by understanding these processes better.
-
Using nutrition and exercise to improve bone health in older adults
This study is looking at how a mix of healthy eating, wearing weighted vests, learning about nutrition, and strength training can help older adults lose weight while keeping their bones strong and healthy.
-
How the brain manages attention and learning
This study is looking at how people learn to change their focus based on their experiences and surroundings, and it aims to understand how this ability to shift attention might be connected to different mental health conditions.
Quick answers
How many clinical trials run by Wake Forest University are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.