Using nutrition and exercise to improve bone health in older adults

Incorporating Nutrition, Vests, Education, and Strength Training in Bone Health (INVEST in Bone Health)

['FUNDING_R01'] · WAKE FOREST UNIVERSITY · NIH-10612980

This study is looking at how a mix of healthy eating, wearing weighted vests, learning about nutrition, and strength training can help older adults lose weight while keeping their bones strong and healthy.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorWAKE FOREST UNIVERSITY (nih funded)
Locations1 site (WINSTON-SALEM, UNITED STATES)
Trial IDNIH-10612980 on ClinicalTrials.gov

What this research studies

This research investigates how combining nutrition, weighted vests, education, and strength training can help maintain bone health in older adults who are trying to lose weight. The approach focuses on using weighted vests to simulate the mechanical stress of body weight, which may help prevent bone loss associated with weight loss. Participants will engage in a program that includes dietary guidance and strength training to support their overall health while minimizing risks to their bones. The study aims to find a more accessible and cost-effective way to promote healthy weight loss without compromising bone density.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults aged 21 and above who are overweight and concerned about maintaining their bone density during weight loss.

Not a fit: Patients who are not overweight or those with pre-existing severe bone conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide older adults with a safer method to lose weight while protecting their bone health.

How similar studies have performed: Previous pilot studies have shown promising results using weighted vests to help maintain bone density during weight loss, indicating potential for success in this approach.

Where this research is happening

WINSTON-SALEM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.