Exploring the use of reactive sulfur and selenium compounds for diagnosing and treating diseases.
Official title: Biomedical Applications of Reactive Sulfur and Selenium Species: Diagnosis and Therapuetics
Funded at Wake Forest University · NIH-11142420 · Data updated 2026-11-12
This study is looking at how certain natural compounds, called reactive sulfur and selenium species, can help improve health and treat diseases like cancer, Alzheimer's, and heart problems, with the goal of finding better ways to deliver and detect these compounds for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project start | August 1, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $363,750 |
| NIH project number | 5R35GM155035-02 |
| Project ID | NIH-11142420 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with Alzheimer's disease, cancer, or other age-related illnesses.
✕Less likely to help
Patients with conditions unrelated to the effects of reactive sulfur and selenium species may not benefit from this research.
What this research studies
This research investigates the role of reactive sulfur species (RSS) and reactive selenium species (RSeS) in human health and disease. It aims to develop effective methods for delivering and detecting these compounds, which have shown potential in treating conditions like cancer, Alzheimer's disease, and cardiovascular issues. By focusing on the biological activities of these compounds, the research seeks to enhance their therapeutic applications and improve patient outcomes. Patients may benefit from advancements in diagnosis and treatment options stemming from this work.
Why it matters
Potential benefit: If successful, this research could lead to new diagnostic tools and therapies for serious conditions like Alzheimer's disease and cancer.
How similar studies have gone: While the exploration of reactive sulfur and selenium species is gaining attention, the specific approaches in this research are relatively novel and have not been extensively tested.
Where this research is happening
-
Wake Forest University
Winston-Salem, United States Active
Researchers
- Principal investigator: Lukesh, John Carl — Wake Forest University
- Study coordinator: Lukesh, John Carl
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.