Remote weight-loss and daily-movement program to ease pain for older adults

A Mobile Health Behavior Intervention to Reduce Pain and Improve Health-III (MORPH-III)

NIH-funded research Wake Forest University · NIH-11191576

A remote group program combining modest calorie reduction and frequent walking to help older adults with knee or hip osteoarthritis and obesity walk more and lessen how much pain disrupts their daily life.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWake Forest University NIH-funded
Lab location1 site (Winston-Salem, United States)
Project IDNIH-11191576 on NIH RePORTER

What this research studies

You would join a remotely delivered group program that teaches a modest calorie-reduction plan plus ways to build more steps throughout each day (short, frequent walking bouts) rather than one long exercise session. The 6-month program is group-mediated and based on social-cognitive and self-determination approaches, with participants randomized to the intervention arm. Activity is tracked with wearable devices (accelerometers) and outcomes include daily steps, pain interference, weight, pain intensity, quality of life, and related behavior-change measures. The study also follows participants for up to 12 months after the program to see if changes last.

Who could benefit from this research

Good fit: Ideal candidates are low-active adults aged 65 or older who have chronic knee or hip osteoarthritic pain and meet criteria for obesity.

Not a fit: People younger than 65, without knee or hip osteoarthritis, not overweight, already highly active, or unable/unwilling to use remote technology or wear an activity monitor may not get benefit from this program.

Why it matters

Potential benefit: If successful, the program could help older adults with knee or hip osteoarthritis and obesity increase daily walking, lose weight, and reduce how much pain interferes with daily activities.

How similar studies have performed: Earlier small pilot trials showed the remote group approach is feasible, acceptable, and showed promising benefits, but a larger randomized trial is needed to confirm results.

Where this research is happening

Winston-Salem, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.