Investigating how muscle power affects knee osteoarthritis in at-risk women
Official title: Muscle Power as a Predictor of Knee Osteoarthritis in At-Risk Females
Funded at Wake Forest University · NIH-11162185 · Data updated 2026-11-12
This study is looking at how strong your knee muscles are and how that might help predict knee osteoarthritis in women who are at risk, so we can find ways to prevent it and improve mobility and pain levels.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project start | May 14, 2025 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $393,883 |
| NIH project number | 1R01AR084828-01A1 |
| Project ID | NIH-11162185 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women who are at risk for knee osteoarthritis, particularly those with factors such as age or obesity.
✕Less likely to help
Patients who are not at risk for knee osteoarthritis or those with advanced OA may not benefit from this research.
What this research studies
This research focuses on understanding the role of muscle power in predicting knee osteoarthritis (OA) among women who are at risk. It aims to measure maximal knee extensor muscle power in participants and analyze how this relates to mobility and pain levels. By leveraging data from an ongoing clinical trial, the study will assess neuromuscular capabilities alongside traditional risk factors like age and obesity. The goal is to identify potential preventative measures for knee OA based on muscle power assessments.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing knee osteoarthritis in at-risk women.
How similar studies have gone: Previous research has shown that muscle power is a significant factor in mobility and pain management in knee OA, suggesting that this approach has potential for success.
Where this research is happening
-
Wake Forest University
Winston-Salem, United States Active
Researchers
- Principal investigator: Rice, Paige Elizabeth — Wake Forest University
- Study coordinator: Rice, Paige Elizabeth
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.