Investigating how muscle power affects knee osteoarthritis in at-risk women

Muscle Power as a Predictor of Knee Osteoarthritis in At-Risk Females

NIH-funded research Wake Forest University · NIH-11162185

This study is looking at how strong your knee muscles are and how that might help predict knee osteoarthritis in women who are at risk, so we can find ways to prevent it and improve mobility and pain levels.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWake Forest University NIH-funded
Lab location1 site (Winston-Salem, United States)
Project IDNIH-11162185 on NIH RePORTER

What this research studies

This research focuses on understanding the role of muscle power in predicting knee osteoarthritis (OA) among women who are at risk. It aims to measure maximal knee extensor muscle power in participants and analyze how this relates to mobility and pain levels. By leveraging data from an ongoing clinical trial, the study will assess neuromuscular capabilities alongside traditional risk factors like age and obesity. The goal is to identify potential preventative measures for knee OA based on muscle power assessments.

Who could benefit from this research

Good fit: Ideal candidates for this research are women who are at risk for knee osteoarthritis, particularly those with factors such as age or obesity.

Not a fit: Patients who are not at risk for knee osteoarthritis or those with advanced OA may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing knee osteoarthritis in at-risk women.

How similar studies have performed: Previous research has shown that muscle power is a significant factor in mobility and pain management in knee OA, suggesting that this approach has potential for success.

Where this research is happening

Winston-Salem, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.