Sponsor or institution
Clinical trials and research at Singapore General Hospital
As of November 12, 2026, Find a Trial lists 29 clinical trials run by Singapore General Hospital that are recruiting, in Singapore. By phase: Phase 2 (2), Phase 4 (1), Phase 2/3 (1), Phase 3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 29Clinical trials
- 1Country
Newest trials
All recruiting trials (29)
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Concise coaching to guide decisions for advanced cancer patients considering palliative procedures
A coaching program delivered by lay providers will test whether it helps adults with advanced cancer make better, patient-aligned decisions about palliative surgeries or similar interventions.
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Treatment Response in Myositis-Associated RP-ILD in Adults
This study tests how people with myositis and rapidly progressing interstitial lung disease respond to an immunosuppressant treatment approach.
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Outpatient physiotherapy vs. mHealth exercise and self-management for knee osteoarthritis
This study tests whether a mobile app–guided, self-managed knee OA exercise program is as good as traditional hospital-based therapy for improving walking speed in adults with knee OA.
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Inhaled Aromatherapy During Wound Debridement for Venous Leg Ulcers
This pilot test will see if inhaling essential oils during a sharp wound debridement helps reduce anxiety and pain for adults with venous leg ulcers.
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Complementary Chinese Herbal Approach to RA Management
This trial tests a modified Si Miao Xiao Bi Tang (Chinese herbal medicine) added to methotrexate to see if it helps people with active rheumatoid arthritis.
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No abdominal incision in minimally invasive colorectal surgery: a multicenter registry of natural orifice specimen extraction
This registry follows adults having minimally invasive colorectal surgery to compare outcomes when the specimen is removed through a natural opening versus through an abdominal incision.
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Outcomes after robotic-assisted total knee replacement using kinematic or functional alignment with randomized implant inserts
This project will test whether two types of knee implant inserts (medial-stabilized versus cruciate-retaining) affect recovery for people having robotic-assisted total knee replacement with either kinematic or functional alignment.
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AS01 adjuvant to boost immune protection in adults
This study tries a single dose of the AS01 adjuvant in healthy adults aged 21–59 to see if it strengthens and trains the immune system and improves response to a later viral vaccine.
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Predicting liver deterioration and death in people with cirrhosis
This project will try to identify clinical signs and lab or imaging markers that predict worsening, acute-on-chronic liver failure (ACLF), or death in adults with cirrhosis treated at Singapore hospitals.
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Pre-hospital wearable cooling after out-of-hospital cardiac arrest
This pilot test tries a battery-free CarbonCool® cooling vest applied by paramedics to adults who regain a pulse after out-of-hospital cardiac arrest but remain unconscious to see if early cooling is feasible and safe.
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Scalp hair chemical changes in people with severe obesity and after bariatric surgery
This project will see if chemicals trapped in scalp hair change with body weight and can signal hair thinning or muscle loss in adults having bariatric surgery.
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Glycine supplementation for MASLD health
This study tests whether adding glycine to the diet helps people with MASLD improve liver fat and metabolic balance.
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Lesion-based molecular decision for focal versus radical prostate treatment
This trial will test whether tumor genetic profiling can help decide if men with localized Grade Group 2–4 prostate cancer should get focal therapy or be advised to have radical treatment.
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Care coach-led palliative surgical and rehabilitation care for people with advanced cancer
This program will test whether a care coach-led palliative surgical oncology approach paired with rehabilitation helps adults with stage 3–4 solid cancers who are planning major elective surgery.
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Community-based care bundle to treat and prevent pressure injuries at home
This program will try a home-based pressure injury care bundle to help older adults discharged home and their caregivers heal existing sores and prevent new ones.
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Using bedside transperineal ultrasound to give visual feedback during pelvic floor exercises after childbirth
This trial will test whether showing postpartum women live ultrasound images of their pelvic floor helps them do pelvic floor exercises more correctly and stay more engaged after a vaginal birth.
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PEAR: an AI chatbot to explain anaesthesia risks and consent.
This trial will test whether PEAR, a multilingual AI chatbot, helps adults having elective surgery understand anaesthesia risks, feel more satisfied, and have less preoperative anxiety compared with the usual face-to-face consent conversation.
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Using Negative Pressure Wound Therapy for Healing Diabetic Foot Wounds
This study tests if using Negative Pressure Wound Therapy along with skin substitutes can help heal diabetic foot wounds better for people who have had toe amputations.
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A program to improve exercise habits among healthcare workers
This study is testing a new 4-week exercise program for healthcare workers to see if it helps them become more active and overcome barriers to regular exercise.
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Mobile app and community coaching for managing type 2 diabetes
This study is testing a mobile app and community coaching to see if they can help people with type 2 diabetes manage their condition better and reach their health goals.
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Comparing drug-coated balloons to plain balloons for treating AVF stenosis
This study is testing if a special drug-coated balloon works better than a regular balloon for treating narrow spots in blood vessels for patients with arteriovenous fistula stenosis.
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Improved community first responder system in Singapore
This project tests whether giving Singapore community first responders a CPR feedback card plus a dispatcher-linked app helps them give higher-quality CPR to adults with out-of-hospital cardiac arrest.
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Observational study on focal therapy for prostate cancer in Asia
This study looks at how well different focal therapy treatments for prostate cancer work and how safe they are for patients in Asia with localized disease.
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Program to Increase Physical Activity in Stroke Survivors
This study is testing if personalized counseling can help stroke survivors become more active compared to those who just get regular care.
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Using an app for motivational interviewing and AI to manage diabetes
This study is testing if using an app that combines motivational support and personalized reminders can help people with Type 2 Diabetes manage their condition better over 36 weeks.
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Using FET PET to Distinguish Tumor Progression from Pseudoprogression in High-Grade Glioma
This study is testing if a special brain scan can help tell the difference between real tumor growth and false alarms in patients with high-grade gliomas after radiation therapy.
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Exploring doctor-patient partnerships in Singapore
This study looks at how the relationships between doctors and patients in Singapore affect care for people with chronic lung disease.
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Evaluating the effects of stopping ixekizumab treatment in plaque psoriasis patients
This study is testing what happens to people with moderate to severe plaque psoriasis after they stop taking ixekizumab treatment to see how it affects their skin, relapse rates, and overall quality of life over two years.
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Collecting data on patients with diffuse lung diseases
This study is collecting information from patients with lung diseases to better understand their causes, how common they are, and how they respond to treatment.
Quick answers
How many clinical trials run by Singapore General Hospital are recruiting right now?
29, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in Singapore. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Phase 4: 1, Phase 2/3: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.