Clinical trial Recruiting at 1 site Interventional Ages 21 to 99

Concise coaching to guide decisions for advanced cancer patients considering palliative procedures

Official title: Serious Illness Coaching for Patients With Advanced Cancer Undergoing Palliative Interventions

Run by Singapore General Hospital · NCT07789093 · Data updated 2026-11-12

A coaching program delivered by lay providers will test whether it helps adults with advanced cancer make better, patient-aligned decisions about palliative surgeries or similar interventions.

Quick facts

Study typeInterventional
Ages21 Years to 99 Years
SexAll
Enrollment220 (estimated)
SponsorSingapore General Hospital
Academic / other
Locations1 site (Singapore)
StatusRecruiting
StartedMarch 24, 2026
Main results expectedMarch 30, 2028
Study endsSeptember 30, 2028
Registry record updatedAugust 27, 2026
Trial IDNCT07789093 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (21+) with advanced (stage 3-4) solid tumors, considered for palliative surgery or other symptom-relieving interventions, who can speak English or Mandarin, and have an unpaid caregiver willing to participate.

Probably not a fit

Patients without significant engagement with decision-making or those excluded due to cognitive or mental health contraindications may see little benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study tests CONCORD, a serious illness coaching program, in adults with advanced cancer who are being considered for palliative procedures. Coaching aims to improve readiness for decision-making, align treatment choices with patient goals, and enhance quality of life, measuring outcomes up to six months after intervention. Trained lay care coaches will deliver the sessions, alongside usual care, to compare effects on decision quality and patient experience. The study addresses gaps in peri-procedural communication and goal-concordant care in high-risk palliative settings. Recruitment is centered at Singapore General Hospital with collaboration from Duke-NUS, and includes English- and Mandarin-speaking participants and their informal caregivers.

Why it matters

Potential benefit: If successful, CONCORD could improve care alignment with patient goals and reduce decisional regret for those facing palliative procedures.

How similar studies have gone: Previous patient-directed coaching has improved coping and end-of-life decision making in advanced cancer, though applicability to palliative surgical decisions is still being explored.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

(i) Patient:

1. Aged 21 or above;
2. Diagnosis of advanced cancer, i.e. stage 3 or 4 solid organ
3. Consulted for palliative surgery or other interventions, i.e. procedures aimed at relieving symptoms and improving quality of life
4. Able to speak English or Mandarin;

(ii) Caregiver

1. Aged 21 or above;
2. Self-endorsed or identified by the enrolled patient as an unpaid spouse/partner, relative or friend who knows them well and who provides regular care, who does not have to live in the same dwelling
3. Able to speak English or Mandarin.

Exclusion Criteria:

(i). Patient

1. Patient refusal,
2. Active mental illness or severe dementia, or being certified unfit to make medical decision by a specialist physician,
3. Pregnant Women

(ii). Caregiver

1. Self-reported severe mental illness, dementia, active suicidal ideation, uncorrected hearing loss;
2. Unable to complete caregiver-reported outcomes.

Where it's running

  • Singapore General Hospital
    Singapore, Singapore
    Recruiting

Study contacts

  • Principal investigator: Jolene Si Min Wong, MBBS, MMed (Surgery), MPH — Singapore General Hospital
  • Study coordinator: Xindi Huang, MSc Psychology
  • Email: huang.xindi@nccs.com.sg
  • Phone: +65 63065636

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.