Outpatient physiotherapy vs. mHealth exercise and self-management for knee osteoarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In Singapore, knee osteoarthritis affects a large and aging population. The trial compares MOKneeTOR, a smartphone-guided exercise and self-management program, with standard hospital outpatient physiotherapy, using a non-inferiority design. Participants are adults 45 and older with knee pain who are referred for conservative care, randomized after baseline assessment and followed for 6 months. Outcomes include physical function (e.g., fast gait speed) and OA-related costs, with assessor blinding and adherence to CONSORT-eHealth principles.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All patients who meet the knee OA clinical criteria (aged ≥45 years, activity-related knee pain, and ≤30 min knee joint stiffness in the morning) will be included,
* an owner of a smartphone,
* an education level of at least 8 years,
* a willingness to be randomized to either MOKneeTOR program or outpatient rehabilitation program,
* an ability to complete baseline assessment.

Exclusion Criteria:

* lower limb joint replacement surgery anticipated within the next 6 months,
* rheumatoid arthritis and other systemic arthritis,
* a previous history of stroke and other major neurological conditions,
* significant back or other non-knee pain,
* pregnant women

Where it's running

• Singapore General Hospital
  Singapore, Singapore Recruiting

Study contacts

• Study coordinator: Yong Hao Pua, PhD
• Email: pua.yong.hao@sgh.com.sg
• Phone: 90575437

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• NPT Feasibility in Knee Osteoarthritis

  This study tests whether NRPT can be safely given to adults with knee osteoarthritis and whether it shows early signals of benefit.

  Recruiting University of California, San Diego · San Diego, California · NCT07917403

• Aquatic exercise for knee osteoarthritis and central sensitization

  A water-based exercise program is being tested to see if it helps people aged 40–65 with knee osteoarthritis who also have central sensitization.

  Recruiting Kirsehir Ahi Evran Universitesi · Kırşehir, Merkez · NCT07883824

• Gender-based test of a graded weight-bearing physiotherapy for knee osteoarthritis

  We’re testing a 6-week, sensory-modulated graded weight-bearing physiotherapy to see if outcomes differ between men and women with knee osteoarthritis.

  Recruiting Shifa Tameer-e-Millat University · Gujar Khan, Punjab Province · NCT07784998

• Does implant type affect knee alignment when using KUNWU robotic surgery

  This trial tests whether two knee implants (Attune vs Persona) used with the KUNWU robotic system result in more accurate knee alignment after total knee replacement.

  Recruiting The University of Hong Kong · Hong Kong, Sandy Bay · NCT07777757

• Digital Rehab Program for knee OA using multisensory gear and digital twin tech

  A digital rehabilitation program with a smart knee brace and real-time feedback is tested to help adults with knee OA improve movement and function at home.

  Recruiting National Taiwan University Hospital · Taipei and 2 other locations · NCT07695168

• Wearable exosuit to help people with knee osteoarthritis move more

  This study tests a wearable exoskeleton (Dephy Exoboot) to see if it helps adults with knee osteoarthritis walk more and reduce pain.

  Recruiting Massachusetts Institute of Technology · Cambridge, Massachusetts · NCT07652437

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.