Outcomes after robotic-assisted total knee replacement using kinematic or functional alignment with randomized implant inserts

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective interventional study enrolls patients undergoing robotic-assisted total knee arthroplasty using the VELYS system. The operating surgeon chooses either kinematic or functional alignment as part of routine care, and within each alignment group participants are randomly assigned to receive a medial-stabilized or a cruciate-retaining insert via a REDCap allocation system. Patient-reported outcome measures are collected before surgery and at scheduled follow-up visits, with secondary clinical and functional measures recorded as predefined outcomes. The design combines real-world surgical practice with a randomized implant comparison to inform implant-related outcomes across alignment techniques.

Why it matters

Who can join: the full rules

\*Inclusion Criteria:\*

* Patients undergoing robotic-assisted total knee arthroplasty using the VELYS system
* Diagnosis of knee osteoarthritis requiring surgical intervention
* Able to provide informed consent
* Willing to complete patient-reported outcome measures

\*\*Exclusion Criteria:\*\*

* Patients undergoing revision knee arthroplasty
* Presence of active infection
* Inability to comply with follow-up assessments
* Severe co-morbidities that may affect surgical outcomes or participation in the study

Where it's running

• Singapore General Hospital
  Singapore, Singapore Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.