Condition

Tobacco Use Cessation clinical trials and research

• 10Clinical trials
• 4NIH research projects
• 2Countries

Newest Tobacco Use Cessation clinical trials

All recruiting trials (10)

• Automating Tobacco Cessation in Primary Care

  This project tests a workflow in primary care to identify smokers and help them access nicotine replacement therapy (NRT) during routine visits.

  Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT07735286

• Text2Quit-Kenya: a mobile message program to help ED patients quit tobacco

  Researchers will test a text message-based smoking-cessation program with Kenyan emergency department patients to see if it helps people quit and learn what works in this setting.

  Recruiting Yale University · Nairobi · NCT07734727

• Extended tobacco support for people experiencing homelessness

  This program tests whether extending tobacco treatment to 6 months with pharmacist counseling, monthly nicotine replacement deliveries, and phone wellness coaching helps adults experiencing homelessness quit smoking compared with a 3-month package.

  Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT07148232

• Trauma-informed smoking cessation support during pregnancy

  This project will test a trauma-informed smoking cessation program that combines the 4Rs with the 5As to help pregnant women who smoke and have histories of trauma.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07129590

• Treatment for quitting cigarettes and reducing cannabis use

  This study tests if a medication called varenicline can help adults who smoke cigarettes and use cannabis quit smoking and cut down on cannabis use, with support from counseling and online resources.

  Recruiting Phase 3 Medical University of South Carolina · Charleston, South Carolina · NCT06883162

• Improving tobacco cessation support for patients in poverty in Utah

  This study is testing new ways to help people living in poverty in Utah quit smoking by using support tools and strategies in their healthcare clinics.

  Recruiting University of Utah · Salt Lake City, Utah · NCT06881069

• Helping pregnant women quit smoking with community health workers

  This study is testing a new program that uses community health workers to help pregnant women in San Bernardino County quit smoking by providing support through home visits.

  Recruiting Loma Linda University · Loma Linda, California and 1 other locations · NCT06438549

• Comprehensive tobacco cessation program for cancer patients, survivors, and caregivers

  This program will try offering gold-standard medications (nicotine replacement, bupropion, or varenicline) plus behavioral counseling to help cancer patients, survivors, and caregivers quit tobacco.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT05805722

• Using Cannabidiol to Help People Quit Smoking

  This study is testing if taking cannabidiol (CBD) can help people who smoke more than 10 cigarettes a day quit smoking and feel better during withdrawal.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT05445804

• Comparing mobile health approaches for quitting smoking in underserved patients

  This study is testing three different ways to help underserved adults quit smoking to see which one works best for them.

  Recruiting University of Florida · Gainesville, Florida · NCT05415761

NIH-funded research (4)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Phone text program to help people with HIV in Uganda and Zambia stop smoking

  This program uses tailored text messages and nicotine patches to help people living with HIV in Uganda and Zambia quit tobacco.

  NIH research Univ of Maryland, College Park · College Park, United States · NIH-11418843

• Tobacco quitting support for people living with HIV in Kisumu County, Kenya

  This project brings tobacco‑cessation help into HIV clinics so people living with HIV in Kisumu can get counseling and support to quit tobacco.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11174528

• Helping people living with HIV in Uganda and Zambia quit smoking using phone-based support.

  This study is testing a helpful phone program that sends supportive text messages to people living with HIV in Uganda and Zambia to help them quit smoking, comparing it to regular care like advice and nicotine patches.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-10915421

• Helping people with HIV quit tobacco in Kenya

  This study is testing a new way to help people living with HIV in Kenya quit smoking by adding support programs right into their regular HIV care, making it easier for them to stop using tobacco and improve their health.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10909243

Related topics

Quick answers

How many Tobacco Use Cessation clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (9 trials), Kenya (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 3: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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