Helping people living with HIV in Uganda and Zambia quit smoking using phone-based support.

Quit4Life+: Adapting and Evaluating a Phone-Based Tobacco Use Cessation Program for People Living with HIV in Uganda and Zambia

NIH-funded research University of Southern California · NIH-10915421

This study is testing a helpful phone program that sends supportive text messages to people living with HIV in Uganda and Zambia to help them quit smoking, comparing it to regular care like advice and nicotine patches.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Southern California NIH-funded
Lab location1 site (Los Angeles, UNITED STATES)
Project IDNIH-10915421 on NIH RePORTER

What this research studies

This research aims to develop and evaluate a phone-based program designed to help individuals living with HIV in Uganda and Zambia quit smoking. It addresses the unique challenges faced by this population, such as higher rates of depression and social stigma, by providing tailored support through text messages. Participants will be involved in a randomized control trial comparing this SMS intervention to standard care, which includes brief advice and nicotine patches. The goal is to assess the effectiveness of this approach in achieving long-term smoking cessation.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV in Uganda and Zambia who are current tobacco users.

Not a fit: Patients who do not smoke or are not living with HIV may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the health outcomes of people living with HIV by reducing smoking-related deaths and enhancing their overall quality of life.

How similar studies have performed: Previous research has shown success in tobacco cessation interventions in general populations, but this specific approach tailored for HIV-positive individuals is novel.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.