NIH-funded research U01 cooperative agreement

Phone text program to help people with HIV in Uganda and Zambia stop smoking

Official title: Quit4Life+: Adapting and Evaluating a Phone-Based Tobacco Use Cessation Program for People Living with HIV in Uganda and Zambia

Funded at Univ of Maryland, College Park · NIH-11418843 · Data updated 2026-11-12

This program uses tailored text messages and nicotine patches to help people living with HIV in Uganda and Zambia quit tobacco.

More Tobacco Use research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniv of Maryland, College Park
NIH-funded
Lab location1 site (College Park, United States)
Project startSeptember 15, 2021
Project endAugust 31, 2026
Funding year2025
Award (this year)$272,847
NIH project number3U01CA261624-05S1
Project IDNIH-11418843 on NIH RePORTER

Who could benefit from this research

Could help

Adults living with HIV who currently use tobacco and receive care at participating HIV clinics in Uganda or Zambia are the ideal candidates.

Less likely to help

People who do not use tobacco, live outside Uganda or Zambia, or are not engaged in HIV care at participating clinics would not benefit from this program.

What this research studies

If you join, you will be randomly assigned to receive either tailored SMS support, brief advice to quit, or nicotine patches while staying in HIV care at local clinics. The text messages are written to address challenges common for people with HIV such as depression, alcohol use, lack of awareness about smoking risks, and stigma. Researchers will follow up by phone and at the clinic to see whether you remain tobacco-free six months after starting. The goal is to find an affordable, clinic-deliverable way to help people with HIV stop using tobacco.

Why it matters

Potential benefit: If successful, the program could help people with HIV stop smoking and reduce tobacco-related illness and deaths in Uganda and Zambia.

How similar studies have gone: Phone-text and nicotine patch approaches have helped smokers in general populations, but this tailored SMS program for people living with HIV in sub-Saharan Africa is new and being tested in a randomized trial.

Where this research is happening

  • Univ of Maryland, College Park
    College Park, United States
    Active

Researchers

  • Principal investigator: Wipfli, Heather L — Univ of Maryland, College Park
  • Study coordinator: Wipfli, Heather L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.