Condition

Tic Disorders clinical trials and research

• 10Clinical trials
• 4NIH research projects
• 6Countries

Newest Tic Disorders clinical trials

All recruiting trials (10)

• Combined ERP and Habit Reversal Therapy for Tourettic OCD

  This study tests whether a merged Exposure and Response Prevention and Habit Reversal Therapy helps adults with Tourettic OCD more than either therapy alone or basic psychoeducation.

  Recruiting at 2 sites University College London Hospitals · London, London and 1 other locations · NCT07725926

• Personalized closed-loop non-invasive brain stimulation to treat tics in children

  This program will test a personalized, closed-loop transcranial magnetic stimulation (TMS) approach to reduce tics in children and adolescents aged 5 to 18.

  Recruiting Shanghai Children's Medical Center · Shanghai, Shanghai Municipality · NCT07351955

• Understanding changes in Tourette Syndrome

  This study is trying to learn how Tourette Syndrome and tic disorders change over time in kids by using new technology to track their symptoms.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT06679790

• Mindfulness intervention for managing tics in Tourette syndrome

  This study is testing a mindfulness program to see if it can help adults with Tourette syndrome manage their tics better than traditional therapy.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT06408662

• Comparing Sertraline and Placebo for Treating Anxiety in Children with Neurodevelopmental Disorders

  This study is testing if the medication sertraline can help reduce anxiety in children and teens aged 8-17 with neurodevelopmental disorders like autism and Fragile X syndrome compared to a placebo.

  Recruiting at 6 sites Phase 2 Holland Bloorview Kids Rehabilitation Hospital · Calgary, Alberta and 6 other locations · NCT06081348

• Characterizing Repetitive Behaviors in OCD and Tic Disorders

  This study is testing if special brain activity measurements can help tell the difference between compulsions in OCD and tics in Tourette syndrome to improve treatment options for people aged 15 to 65.

  Recruiting at 3 sites Institut National de la Santé Et de la Recherche Médicale, France · Créteil and 2 other locations · NCT06050369

• Mobile app-assisted treatment for children and adolescents with tics

  This study tests whether a mobile app can help children and teens with tic disorders manage their symptoms better and stick to their treatment plans.

  Recruiting Aarhus University Hospital · Aarhus N, Risskov · NCT05390268

• Behavioral intervention for tic disorders in youth

  This study tests if a special therapy called Comprehensive Behavioral Intervention for Tics can help young people with tic disorders feel better and function better in their daily lives.

  Recruiting University of Miami · Coral Gables, Florida · NCT05370391

• Validation of a deep learning platform for diagnosing isolated dystonia

  This study is testing a new deep learning tool to see if it can help doctors diagnose isolated dystonia more accurately and quickly.

  Recruiting Massachusetts Eye and Ear Infirmary · Boston, Massachusetts · NCT05317390

• Registry for adults with tic disorders

  This study is creating a registry for adults with tic disorders to see how tic severity affects their daily lives and to understand any differences between men and women.

  Recruiting at 7 sites Assistance Publique - Hôpitaux de Paris · Clermont-Ferrand and 6 other locations · NCT05090943

NIH-funded research (4)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Zebrafish and mouse models to study tic disorders

  Researchers are building quick, scalable animal models to understand tic disorders and to test potential therapies.

  NIH research University of Florida · Gainesville, United States · NIH-11421302

• Dopamine imbalances in OCD and tic disorders explored with brain imaging

  A patient-focused look at how dopamine signaling in specific brain areas relates to OCD and tic disorders using PET imaging.

  NIH research Yale University · New Haven, United States · NIH-11330470

• Understanding dopamine receptor changes in OCD and tic disorders

  This study is looking at how certain brain receptors related to dopamine work differently in people with obsessive-compulsive disorder and tic disorders like Tourette syndrome, using special imaging to help find better ways to treat these conditions.

  NIH research Yale University · New Haven, United States · NIH-11088268

• Using fractality to assess tic disorders and tic-like behaviors in children

  This study is looking at how certain movement patterns can help us better understand and treat tic disorders and tic-like behaviors in children, so we can tell the difference between them and find the best ways to help kids who are dealing with these challenges.

  NIH research Washington University · Saint Louis, United States · NIH-10728174

Related topics

Quick answers

How many Tic Disorders clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (4 trials), France (2 trials), Canada (1 trial), Denmark (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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