NIH-funded research R21 grant

Using fractality to assess tic disorders and tic-like behaviors in children

Official title: Fractality as a quantitative assessment tool for tic disorders and functional tic-like behaviors

Funded at Washington University · NIH-10728174 · Data updated 2026-11-12

This study is looking at how certain movement patterns can help us better understand and treat tic disorders and tic-like behaviors in children, so we can tell the difference between them and find the best ways to help kids who are dealing with these challenges.

More Tic Disorders research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionWashington University
NIH-funded
Lab location1 site (Saint Louis, United States)
Project startAugust 15, 2023
Project endJuly 31, 2025
Funding year2023
Award (this year)$427,625
NIH project number1R21NS133875-01
Project IDNIH-10728174 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 0-11 years who exhibit tic disorders or tic-like behaviors.

Less likely to help

Patients who do not have tic disorders or functional tic-like behaviors may not benefit from this research.

What this research studies

This research investigates how fractality can be used as a quantitative tool to assess tic disorders and functional tic-like behaviors in children. It focuses on understanding the natural history of tics, which often begin in early childhood and can vary in severity. The study aims to differentiate between typical tic disorders and functional tic-like behaviors, which have become more prevalent in recent years. By analyzing movement patterns, the research seeks to improve diagnosis and treatment strategies for affected children.

Why it matters

Potential benefit: If successful, this research could lead to better diagnostic tools and treatment options for children with tic disorders and functional tic-like behaviors.

How similar studies have gone: While the use of fractality in this context is relatively novel, other studies have shown promise in using quantitative assessments for movement disorders.

Where this research is happening

  • Washington University
    Saint Louis, United States
    Active

Researchers

  • Principal investigator: Black, Kevin J — Washington University
  • Study coordinator: Black, Kevin J

Related research

Other NIH-funded projects on the same topics.

  • Zebrafish and mouse models to study tic disorders

    Researchers are building quick, scalable animal models to understand tic disorders and to test potential therapies.

    NIH research University of Florida · Gainesville, United States · NIH-11421302

  • Dopamine imbalances in OCD and tic disorders explored with brain imaging

    A patient-focused look at how dopamine signaling in specific brain areas relates to OCD and tic disorders using PET imaging.

    NIH research Yale University · New Haven, United States · NIH-11330470

  • Understanding dopamine receptor changes in OCD and tic disorders

    This study is looking at how certain brain receptors related to dopamine work differently in people with obsessive-compulsive disorder and tic disorders like Tourette syndrome, using special imaging to help find better ways to treat these conditions.

    NIH research Yale University · New Haven, United States · NIH-11088268

  • Combined ERP and Habit Reversal Therapy for Tourettic OCD

    This study tests whether a merged Exposure and Response Prevention and Habit Reversal Therapy helps adults with Tourettic OCD more than either therapy alone or basic psychoeducation.

    Recruiting at 2 sites University College London Hospitals · London, London and 1 other locations · NCT07725926

  • Personalized closed-loop non-invasive brain stimulation to treat tics in children

    This program will test a personalized, closed-loop transcranial magnetic stimulation (TMS) approach to reduce tics in children and adolescents aged 5 to 18.

    Recruiting Shanghai Children's Medical Center · Shanghai, Shanghai Municipality · NCT07351955

  • Understanding changes in Tourette Syndrome

    This study is trying to learn how Tourette Syndrome and tic disorders change over time in kids by using new technology to track their symptoms.

    Recruiting University of Minnesota · Minneapolis, Minnesota · NCT06679790

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.