Understanding changes in Tourette Syndrome
Trajectories of Change in Tourette Syndrome
NA · University of Minnesota · NCT06679790
This study is trying to learn how Tourette Syndrome and tic disorders change over time in kids by using new technology to track their symptoms.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 12 Years to 17 Years |
| Sex | All |
| Sponsor | University of Minnesota (other) |
| Locations | 1 site (Minneapolis, Minnesota) |
| Trial ID | NCT06679790 on ClinicalTrials.gov |
What this trial studies
This observational study aims to gather data on the trajectories of change in individuals with Tourette Syndrome and tic disorders. The principal investigator will utilize advanced methods for data collection, including electronic momentary assessment and wearable devices, to analyze tic severity and patterns over time. The study focuses on training the investigator in leading pediatric clinical trials and managing large datasets to enhance understanding of tic disorders. The findings may contribute to the development of more effective interventions for affected individuals.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with chronic motor and/or vocal tics who have a moderate severity of symptoms.
Not a fit: Patients with a history of psychosis, cognitive disabilities, or those currently experiencing suicidal intent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of Tourette Syndrome, potentially enhancing treatment options for patients.
How similar studies have performed: While this study builds on existing knowledge in tic disorders, the specific approach of integrating multi-method data collection is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Presence of chronic motor and/or vocal tics, defined as tics for at least 1 year without a tic-free period of more than 3 consecutive months. Tics must not be due to a medical condition or the direct physiological effects of a substance. 2. At least moderate tic severity, defined as a Yale Global Tic Severity Scale44 total score ≥14 (≥9 for those with motor or vocal tics only). 3. Participants must be fluent in English to ensure comprehension of study measures and instructions. Exclusion Criteria: 1. Previous diagnosis of psychosis or cognitive disability, 2. IQ \< 80, 3. Substance abuse or dependence within the past year. 4. Current suicidal intent. 5. Changes in medication in the previous 4 weeks.
Where this trial is running
Minneapolis, Minnesota
- University of Minnesota — Minneapolis, Minnesota, United States (RECRUITING)
Study contacts
- Principal investigator: Brianna Wellen — University of Minnesota
- Study coordinator: IaOom Khang
- Phone: 612-624-7830
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Tourette Syndrome, Tic Disorders