Understanding changes in Tourette Syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to gather data on the trajectories of change in individuals with Tourette Syndrome and tic disorders. The principal investigator will utilize advanced methods for data collection, including electronic momentary assessment and wearable devices, to analyze tic severity and patterns over time. The study focuses on training the investigator in leading pediatric clinical trials and managing large datasets to enhance understanding of tic disorders. The findings may contribute to the development of more effective interventions for affected individuals.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Presence of chronic motor and/or vocal tics, defined as tics for at least 1 year without a tic-free period of more than 3 consecutive months. Tics must not be due to a medical condition or the direct physiological effects of a substance.
2. At least moderate tic severity, defined as a Yale Global Tic Severity Scale44 total score ≥14 (≥9 for those with motor or vocal tics only).
3. Participants must be fluent in English to ensure comprehension of study measures and instructions.

Exclusion Criteria:

1. Previous diagnosis of psychosis or cognitive disability,
2. IQ \< 80,
3. Substance abuse or dependence within the past year.
4. Current suicidal intent.
5. Changes in medication in the previous 4 weeks.

Where it's running

• University of Minnesota
  Minneapolis, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Brianna Wellen — University of Minnesota
• Study coordinator: IaOom Khang
• Phone: 612-624-7830

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Combined ERP and Habit Reversal Therapy for Tourettic OCD

  This study tests whether a merged Exposure and Response Prevention and Habit Reversal Therapy helps adults with Tourettic OCD more than either therapy alone or basic psychoeducation.

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• Personalized closed-loop non-invasive brain stimulation to treat tics in children

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• Nature- and activity-based group programs for neurodivergent children and youth in Agder

  This project will try outdoor and activity-based group programs to see if they help children and teens with ADHD, autism, Tourette's, and related neurodivergent challenges feel better, gain confidence, and do better in daily life.

  Recruiting at 2 sites Sorlandet Hospital HF · Kristiansand, Agder and 1 other locations · NCT07203469

• Study of brain activity in patients with Tourette Syndrome

  This study is testing how brain activity changes in adults with severe Tourette Syndrome who are getting deep brain stimulation to better understand their tics.

  Recruiting University Hospital, Bordeaux · Bordeaux · NCT06909656

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.