Condition

Tetraplegia clinical trials and research

• 17Clinical trials
• 6NIH research projects
• 5Countries

Newest Tetraplegia clinical trials

All recruiting trials (17)

• Portable control systems to operate a hand motor neuroprosthesis for people with tetraplegia

  The study will test whether several fully portable, non‑invasive control methods (for example shoulder‑motion IMUs, surface EMG, touch/contact sensors, and voice) let adults with tetraplegia reliably control a hand motor neuroprosthesis.

  Recruiting Centre Bouffard Vercelli - USSAP · Perpignan · NCT07058506

• Improving hand function in cervical spinal cord injury with nerve transfers and electrical stimulation

  This study is testing if using electrical stimulation during and after nerve surgery can help people with cervical spinal cord injuries regain hand function and feel less pain.

  Recruiting Stanford University · Palo Alto, California · NCT06541041

• Using a brain-computer interface to help people with tetraplegia communicate

  This study is testing a new brain-computer interface to help people with tetraplegia communicate more easily using a tablet.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT06511934

• Nerve transfer surgery to enhance function in high tetraplegia

  This study is testing if nerve transfer surgery can help people with high spinal cord injuries improve their arm function and quality of life.

  Recruiting at 9 sites Washington University School of Medicine · Stanford, California and 9 other locations · NCT06288763

• Using a brain-computer interface to help people with speech difficulties communicate

  This study is testing a brain-computer interface to help people who can't speak due to conditions like ALS communicate by turning their thoughts into speech.

  Recruiting Massachusetts General Hospital · Sacramento, California · NCT06094205

• MindEx multifocal cognitive brain‑machine interface for people with severe paralysis

  This trial will test the MindEx system, which uses four tiny implanted brain chips to let people with severe paralysis control a computer or tablet with their thoughts.

  Recruiting University of Texas Southwestern Medical Center · Dallas, Texas · NCT05936619

• Evaluating a device to help patients with motor disabilities control external equipment

  This study is testing a new device that helps people with motor disabilities, like tetraplegia, control things like wheelchairs and robotic arms using their brain signals.

  Recruiting at 3 sites Neuracle Medical Technology(Shanghai) Co.,Ltd. · Beijing, Beijing Municipality and 3 other locations · NCT05920174

• Using a neural interface to help people with tetraplegia control devices with their thoughts

  This study is testing a new brain interface that helps people with tetraplegia, especially those with ALS, control devices like computers just by thinking about it.

  Recruiting at 2 sites Massachusetts General Hospital · Stanford, California and 1 other locations · NCT05724173

• Brain-controlled spinal cord stimulation for upper limb rehabilitation in cervical spinal cord injury

  This study is testing a new brain-controlled device to help people with cervical spinal cord injuries regain movement in their arms and hands.

  Recruiting Ecole Polytechnique Fédérale de Lausanne · Lausanne, Canton of Vaud · NCT05665998

• A device to assist hand function for people with spinal cord injuries

  This study is testing a new device called MyHand-SCI to see if it can help people with C6-C7 spinal cord injuries improve their hand function and daily activities.

  Recruiting Columbia University · New York, New York · NCT05553457

• Feasibility of the ReHAB System for Tetraplegia

  This study is testing a new system that uses brain implants to help people with tetraplegia regain some movement in their arms and hands.

  Recruiting University Hospitals Cleveland Medical Center · Cleveland, Ohio · NCT03898804

• Investigation of a brain-computer interface system for communication in patients with severe disabilities

  This study is testing a new brain-computer interface that helps people with severe disabilities, like tetraplegia and ALS, communicate better by using signals from their brain.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT03567213

• Investigation of a brain-computer interface for tetraplegia rehabilitation

  This study is testing a new brain-computer system to see if it can help people with tetraplegia regain movement and feel sensations again.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT03161067

• Using brain-machine interface technology to help individuals with severe paralysis control devices

  This study tests if people with severe paralysis can use a brain-machine interface to control devices just by thinking, helping them interact with the world despite their inability to move.

  Recruiting at 2 sites University of Pittsburgh · Chicago, Illinois and 1 other locations · NCT01894802

• A device to improve sitting posture and balance for individuals with spinal cord injuries

  This study is testing a new device that helps people with spinal cord injuries sit better and improve their balance by using electrical stimulation to strengthen their muscles.

  Recruiting VA Office of Research and Development · Cleveland, Ohio · NCT01474148

• Feasibility of a brain-computer interface for people with tetraplegia

  This study is testing a new brain-computer interface that helps people with tetraplegia control a computer and other devices just by thinking, to see if it’s safe and effective.

  Recruiting at 6 sites Massachusetts General Hospital · Sacramento, California and 5 other locations · NCT00912041

• Evaluation of a neuroprosthesis for improving mobility in paralyzed individuals

  This study is testing a new device that helps people with paralysis improve their movement and balance through a special electrical stimulation system implanted in their muscles.

  Recruiting at 2 sites Case Western Reserve University · Cleveland, Ohio and 1 other locations · NCT00623389

NIH-funded research (6)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Adaptive EMG-controlled skiing for people with high-level spinal cord injury

  Aims to let people with severe spinal cord injuries control assistive devices more naturally using leftover muscle signals, starting with downhill skiing in a specialized ski.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11424905

• Optimizing sensory feedback to improve function after tetraplegia

  Aimed at people with tetraplegia, this project tests new ways to restore natural-feeling touch through brain and nerve stimulation to improve how they reach, grasp, and use everyday activities.

  NIH research Case Western Reserve University · Cleveland, United States · NIH-11378279

• FES+BMI Neuroprosthesis for Home Use in Chronic Tetraplegia

  A home-use brain-controlled hand prosthesis that helps people with chronic spinal cord injury regain everyday hand movements.

  NIH research Louis Stokes Cleveland VA Medical Center · Cleveland, United States · NIH-11262850

• Using a mobile robot to help people with severe spinal cord injuries live more independently

  This study is working on a friendly robot that can help people with tetraplegia do everyday tasks like bathing, dressing, and eating, making life a little easier and more independent while also supporting their emotional needs.

  NIH research Charles River Analytics, INC. · Cambridge, United States · NIH-11180646

• Using spinal cord stimulation to improve arm and hand movement in people with tetraplegia

  This study is looking at how a special electrical stimulation technique can help veterans with neck injuries improve their arm and hand movements, making everyday tasks like reaching and grabbing easier and more effective.

  NIH research Edward Hines Jr VA Hospital · Hines, United States · NIH-11002668

• Creating a device to help people with paralysis use their hands at home

  This study is testing a new device that helps people with paralysis in their arms and hands regain control of their movements, so they can do everyday tasks like eating on their own, and we’re looking for participants to help us make it work better for home use.

  NIH research Louis Stokes Cleveland VA Medical Center · Cleveland, United States · NIH-11000647

Related topics

Quick answers

How many Tetraplegia clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (14 trials), Switzerland (1 trial), Canada (1 trial), China (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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