NIH-funded research NIH-funded research

FES+BMI Neuroprosthesis for Home Use in Chronic Tetraplegia

Official title: Development of FES+BMI Neuroprosthesis for At-Home Use for Persons with Chronic Tetraplegia

Funded at Louis Stokes Cleveland VA Medical Center · NIH-11262850 · Data updated 2026-11-12

A home-use brain-controlled hand prosthesis that helps people with chronic spinal cord injury regain everyday hand movements.

More Tetraplegia research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLouis Stokes Cleveland VA Medical Center
NIH-funded
Lab location1 site (Cleveland, United States)
Project startOctober 1, 2025
Project endSeptember 30, 2029
Funding year2027
NIH project number5I01RX005072-02
Project IDNIH-11262850 on NIH RePORTER

Who could benefit from this research

Could help

Adults with chronic tetraplegia due to spinal cord injury who have or could receive implanted FES and brain-machine interface components.

Less likely to help

People without access to implanted hardware or with medical contraindications for implantation may not benefit.

What this research studies

This project aims to bring a brain-controlled hand and arm prosthesis home for people living with chronic tetraplegia from spinal cord injury. It combines electrical stimulation of muscles with an implanted brain interface to interpret movement intent and drive the reanimated hand. Earlier work showed a person with tetraplegia performing basic daily tasks in the lab; now the team plans to advance the system for real-world use. The effort includes improving muscle control with refined nerve cuffs and expanding brain-machine recording to enhance dexterity.

Why it matters

Potential benefit: If successful, participants could perform daily tasks more independently at home with a more natural and intuitive control of their hand.

How similar studies have gone: Previous demonstrations show proof-of-concept success in laboratory settings, with gradual progression toward real-world use.

Where this research is happening

  • Louis Stokes Cleveland VA Medical Center
    Cleveland, United States
    Active

Researchers

  • Principal investigator: Ajiboye, Abidemi Bolu — Louis Stokes Cleveland VA Medical Center
  • Study coordinator: Ajiboye, Abidemi Bolu

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.