FES+BMI Neuroprosthesis for Home Use in Chronic Tetraplegia
Official title: Development of FES+BMI Neuroprosthesis for At-Home Use for Persons with Chronic Tetraplegia
Funded at Louis Stokes Cleveland VA Medical Center · NIH-11262850 · Data updated 2026-11-12
A home-use brain-controlled hand prosthesis that helps people with chronic spinal cord injury regain everyday hand movements.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louis Stokes Cleveland VA Medical Center NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | October 1, 2025 |
| Project end | September 30, 2029 |
| Funding year | 2027 |
| NIH project number | 5I01RX005072-02 |
| Project ID | NIH-11262850 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with chronic tetraplegia due to spinal cord injury who have or could receive implanted FES and brain-machine interface components.
✕Less likely to help
People without access to implanted hardware or with medical contraindications for implantation may not benefit.
What this research studies
This project aims to bring a brain-controlled hand and arm prosthesis home for people living with chronic tetraplegia from spinal cord injury. It combines electrical stimulation of muscles with an implanted brain interface to interpret movement intent and drive the reanimated hand. Earlier work showed a person with tetraplegia performing basic daily tasks in the lab; now the team plans to advance the system for real-world use. The effort includes improving muscle control with refined nerve cuffs and expanding brain-machine recording to enhance dexterity.
Why it matters
Potential benefit: If successful, participants could perform daily tasks more independently at home with a more natural and intuitive control of their hand.
How similar studies have gone: Previous demonstrations show proof-of-concept success in laboratory settings, with gradual progression toward real-world use.
Where this research is happening
-
Louis Stokes Cleveland VA Medical Center
Cleveland, United States Active
Researchers
- Principal investigator: Ajiboye, Abidemi Bolu — Louis Stokes Cleveland VA Medical Center
- Study coordinator: Ajiboye, Abidemi Bolu
Related research
Other NIH-funded projects on the same topics.
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Adaptive EMG-controlled skiing for people with high-level spinal cord injury
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Optimizing sensory feedback to improve function after tetraplegia
Aimed at people with tetraplegia, this project tests new ways to restore natural-feeling touch through brain and nerve stimulation to improve how they reach, grasp, and use everyday activities.
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Using a mobile robot to help people with severe spinal cord injuries live more independently
This study is working on a friendly robot that can help people with tetraplegia do everyday tasks like bathing, dressing, and eating, making life a little easier and more independent while also supporting their emotional needs.
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Using spinal cord stimulation to improve arm and hand movement in people with tetraplegia
This study is looking at how a special electrical stimulation technique can help veterans with neck injuries improve their arm and hand movements, making everyday tasks like reaching and grabbing easier and more effective.
-
Creating a device to help people with paralysis use their hands at home
This study is testing a new device that helps people with paralysis in their arms and hands regain control of their movements, so they can do everyday tasks like eating on their own, and we’re looking for participants to help us make it work better for home use.
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Portable control systems to operate a hand motor neuroprosthesis for people with tetraplegia
The study will test whether several fully portable, non‑invasive control methods (for example shoulder‑motion IMUs, surface EMG, touch/contact sensors, and voice) let adults with tetraplegia reliably control a hand motor neuroprosthesis.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.