Condition

Radiation Toxicity clinical trials and research

• 19Clinical trials
• 2NIH research projects
• 13Countries

Newest Radiation Toxicity clinical trials

All recruiting trials (19)

• Ozone therapy for refractory pain and quality of life in cancer patients

  This study looks at whether adjuvant ozone therapy can improve quality of life for adults with difficult-to-treat cancer-related symptoms referred to a palliative pain unit.

  Recruiting Hospital Universitario de Gran Canaria Doctor Negrín · Las Palmas de Gran Canaria, Las Palmas · NCT07325851

• Gut microbiome in gynecologic cancer patients with pelvic toxicity

  This study looks at whether gut bacteria profiles relate to pelvic toxicity after cancer treatment and how rectal ozone therapy might affect the gut microbiome and symptoms in women with gynecologic tumors.

  Recruiting at 2 sites Hospital Universitario de Gran Canaria Doctor Negrín · Las Palmas de Gran Canaria, Las Palmas and 1 other locations · NCT07259681

• Curative chest re‑irradiation for thoracic cancers

  This project will try a standardized high‑dose re‑radiation approach for adults with recurrent or new thoracic cancers who previously received chest radiotherapy to see how well it controls disease and what toxicities occur.

  Recruiting University of Aarhus · Aarhus, Jutland · NCT06950073

• First-line bevacizumab versus dexamethasone for symptomatic cerebral radiation necrosis after radiation for high-grade glioma or brain metastases.

  This trial will test whether first-line bevacizumab or dexamethasone works better at reducing symptoms in adults with symptomatic cerebral radiation necrosis after radiation for high-grade glioma or brain metastases.

  Recruiting at 5 sites Phase 3 The Netherlands Cancer Institute · Amsterdam and 5 other locations · NCT06888817

• Evaluating the effects of radiotherapy in pediatric and adult patients with childhood cancers

  This study looks at how radiation therapy affects both kids and adults who had childhood cancers, checking for any side effects and how well it works over time.

  Recruiting Centro di Riferimento Oncologico - Aviano · Aviano, Pordenone · NCT06639165

• Using MR-Linac for precise radiotherapy in cancer treatment

  This study is testing if a new type of radiation therapy using MR-Linac can help cancer patients have better treatment outcomes and improve their quality of life.

  Recruiting The Second Affiliated Hospital of Hainan Medical University · Haikou · NCT06531681

• Post-operative proton radiotherapy for thymus tumors

  This study is testing if proton radiotherapy after surgery can help patients with advanced thymus tumors live longer and feel better, while also looking at any side effects.

  Recruiting Phase 2 Shanghai Proton and Heavy Ion Center · Shanghai, Shanghai Municipality · NCT06311968

• New target method for treating high-grade glioma patients

  This study tests a new way of targeting radiation treatment for patients with high-grade glioma to see if it helps them live longer without their cancer getting worse and reduces side effects compared to the standard method.

  Recruiting Zhujiang Hospital · Guangzhou · NCT06215495

• Pre-rehabilitation for women receiving pelvic radiation therapy

  This study is testing if adding pelvic health physical therapy to radiation treatment can help women with certain cancers feel better and improve their quality of life.

  Recruiting at 3 sites Indiana University · Avon, Indiana and 2 other locations · NCT06059586

• Impact of different radiation therapies on cognitive function in meningioma patients

  This study is testing how different types of radiation therapy affect thinking and memory in patients with certain brain tumors.

  Recruiting Centre Francois Baclesse · Caen and 2 other locations · NCT06036706

• Analyzing how individual children respond to radiation in cancer treatment

  This study is testing how different children react to radiation during cancer treatment to help doctors give safer and more effective care.

  Recruiting Neolys · Caen and 1 other locations · NCT06033183

• Topical gel and mouthwash to prevent severe oral mucositis in people receiving head and neck radiation

  This will test whether a topical gel and mouthwash (XCM-OM118) can reduce severe oral mucositis and improve quality of life for adults having radiation for head and neck cancer.

  Recruiting Mucosa Innovations, S.L. · Madrid, Madrid · NCT05635929

• Determining the best dose of lisinopril to prevent urinary issues after prostate cancer radiotherapy

  This study is testing the best dose of lisinopril to see if it can help men with prostate cancer avoid urinary problems after radiation treatment.

  Recruiting Early Phase 1 University of Rochester · Rochester, New York · NCT05530655

• Registry of patients treated with heavy particle therapy for cancer

  This study is collecting information from cancer patients treated with advanced heavy particle therapy to see how well it works and what side effects it might cause.

  Recruiting CNAO National Center of Oncological Hadrontherapy · Pavia · NCT05203250

• Post-surgery radiation therapy for prostate cancer

  This study tests if a new type of focused radiation therapy given after prostate surgery can help prevent cancer from coming back while keeping side effects and quality of life in check for patients.

  Recruiting University of Milano Bicocca · Rozzano, MI and 1 other locations · NCT04831970

• Effects of SCFA supplements on GI toxicity in cancer patients receiving radiation therapy

  This study is testing if taking short chain fatty acid supplements can help reduce stomach and gut problems in cancer patients getting radiation therapy.

  Recruiting Phase 1/2 UNC Lineberger Comprehensive Cancer Center · Chapel Hill, North Carolina · NCT04700527

• Assessing cognitive function in brain tumor patients after radiation therapy

  This study is trying to see how radiation therapy affects thinking skills over time in patients with primary brain tumors, except glioblastoma, by checking their cognitive function at different points after treatment.

  Recruiting at 5 sites University of Aarhus · Copenhagen, Capital Region and 4 other locations · NCT04306432

• Evaluating the impact of MR-guided radiation therapy on cancer treatment outcomes

  This study is testing how using a special type of radiation therapy with real-time imaging can improve treatment results and quality of life for adults with cancer.

  Recruiting at 14 sites UMC Utrecht · Pittsburgh, Pennsylvania and 17 other locations · NCT04075305

• Comparing two types of radiation therapy for prostate cancer recurrence after surgery

  This study is testing whether a new type of radiation therapy works better than the standard treatment for men whose prostate cancer has come back after surgery.

  Recruiting at 2 sites Asan Medical Center · Seoul and 1 other locations · NCT03920033

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Reducing radiation damage for sarcoma with ultra-fast 'FLASH' proton therapy

  This project compares ultra-fast 'FLASH' proton radiation with standard proton therapy to see if people treated for sarcoma have fewer side effects.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11298924

• Comparing FLASH proton therapy to standard radiation for treating sarcoma

  This study is looking at a new type of radiation therapy called FLASH proton radiotherapy to see if it can treat soft tissue sarcomas while causing fewer side effects than the usual radiation therapy, so patients can have a better experience and healthier outcomes.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11030333

Related topics

Quick answers

How many Radiation Toxicity clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in Italy (4 trials), United States (4 trials), Denmark (3 trials), China (3 trials), Spain (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 3: 1, Phase 1/2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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