Clinical trial Recruiting at 1 site Observational

Registry of patients treated with heavy particle therapy for cancer

Official title: CNAO REgistry triAL - REGAL

Run by CNAO National Center of Oncological Hadrontherapy · NCT05203250 · Data updated 2026-11-12

This study is collecting information from cancer patients treated with advanced heavy particle therapy to see how well it works and what side effects it might cause.

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Quick facts

Study typeObservational
SexAll
Enrollment3000 (estimated)
SponsorCNAO National Center of Oncological Hadrontherapy
Academic / other
Drugs / interventionsradiation
Locations1 site (Pavia)
StatusRecruiting
StartedJune 4, 2021
Main results expectedJune 4, 2030
Study endsJune 4, 2071
Registry record updatedAugust 6, 2025
Trial IDNCT05203250 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include cancer patients who have been treated with heavy particles at the CNAO and can provide informed consent.

Probably not a fit

Patients who are unable to understand the informed consent document or have not received treatment with heavy particles will not benefit from this registry.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This registry collects both retrospective and prospective data from patients treated with particle therapy, specifically protons and carbon ions, at the National Center for Oncological Hadrontherapy in Pavia. The aim is to analyze and evaluate clinical outcomes and side effects associated with this advanced form of radiotherapy, which is particularly effective for tumors that are resistant to conventional treatments. By gathering comprehensive data on the natural history of cancer and treatment effects, the registry seeks to enhance understanding of the role of heavy particle therapy in oncology. This initiative will provide valuable insights for future clinical applications and improve patient care.

Why it matters

Potential benefit: If successful, this registry could lead to improved treatment protocols and outcomes for cancer patients receiving heavy particle therapy.

How similar studies have gone: Other studies on particle therapy have shown promising results, indicating that this approach is gaining recognition in the field of oncology.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients treated with heavy particles at Fondazione CNAO, Pavia
* Patients who have the ability to understand and be willing to sign a written informed consent document

Exclusion Criteria:

* Patients or legal guardians who are unable to understand informed consent document

Where it's running

  • National Center for Oncological Hadrontherapy (CNAO)
    Pavia, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.