Registry of patients treated with heavy particle therapy for cancer
Official title: CNAO REgistry triAL - REGAL
Run by CNAO National Center of Oncological Hadrontherapy · NCT05203250 · Data updated 2026-11-12
This study is collecting information from cancer patients treated with advanced heavy particle therapy to see how well it works and what side effects it might cause.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 3000 (estimated) |
| Sponsor | CNAO National Center of Oncological Hadrontherapy Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Pavia) |
| Status | Recruiting |
| Started | June 4, 2021 |
| Main results expected | June 4, 2030 |
| Study ends | June 4, 2071 |
| Registry record updated | August 6, 2025 |
| Trial ID | NCT05203250 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include cancer patients who have been treated with heavy particles at the CNAO and can provide informed consent.
✕Probably not a fit
Patients who are unable to understand the informed consent document or have not received treatment with heavy particles will not benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This registry collects both retrospective and prospective data from patients treated with particle therapy, specifically protons and carbon ions, at the National Center for Oncological Hadrontherapy in Pavia. The aim is to analyze and evaluate clinical outcomes and side effects associated with this advanced form of radiotherapy, which is particularly effective for tumors that are resistant to conventional treatments. By gathering comprehensive data on the natural history of cancer and treatment effects, the registry seeks to enhance understanding of the role of heavy particle therapy in oncology. This initiative will provide valuable insights for future clinical applications and improve patient care.
Why it matters
Potential benefit: If successful, this registry could lead to improved treatment protocols and outcomes for cancer patients receiving heavy particle therapy.
How similar studies have gone: Other studies on particle therapy have shown promising results, indicating that this approach is gaining recognition in the field of oncology.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients treated with heavy particles at Fondazione CNAO, Pavia * Patients who have the ability to understand and be willing to sign a written informed consent document Exclusion Criteria: * Patients or legal guardians who are unable to understand informed consent document
Where it's running
-
National Center for Oncological Hadrontherapy (CNAO)
Pavia, Italy Recruiting
Study contacts
- Study coordinator: Chiara Campo, PhD
- Email: campo@cnao.it
- Phone: +39 0382078407
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.