Clinical trial Recruiting at 1 site Observational Ages 18 to 75

Using MR-Linac for precise radiotherapy in cancer treatment

Official title: The Second Affiliated Hospital of Hainan Medical University

Run by The Second Affiliated Hospital of Hainan Medical University · NCT06531681 · Data updated 2026-11-12

This study is testing if a new type of radiation therapy using MR-Linac can help cancer patients have better treatment outcomes and improve their quality of life.

Quick facts

Study typeObservational
Ages18 Years to 75 Years
SexAll
Enrollment3000 (estimated)
SponsorThe Second Affiliated Hospital of Hainan Medical University
Academic / other
Locations1 site (Haikou)
StatusRecruiting
StartedAugust 19, 2023
Main results expectedDecember 31, 2028
Study endsDecember 31, 2028
Registry record updatedFebruary 13, 2025
Trial IDNCT06531681 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients aged 18-75 with an ECOG score of 0-2 who are undergoing or have undergone treatment with MR-Linac.

Probably not a fit

Patients with contraindications to MRI or severe comorbidities that prevent them from tolerating radiotherapy may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the effectiveness of magnetic resonance-guided linear accelerator (MR-Linac) technology in delivering precision radiotherapy for tumors. It will analyze various outcomes including overall response rate, progression-free survival, disease control rate, overall survival, and the incidence of adverse reactions. Additionally, the study will assess the quality of life of patients using standardized measures and evaluate dosimetric parameters related to treatment. The study will involve patients aged 18-75 who have undergone imaging or treatment with MR-Linac.

Why it matters

Potential benefit: If successful, this approach could lead to improved tumor response rates and reduced side effects for cancer patients undergoing radiotherapy.

How similar studies have gone: While the use of MR-Linac is a relatively novel approach, preliminary studies have shown promising results in improving precision in radiotherapy.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients are undergoing or have undergone imaging or treatment at the MR linac;
* Age 18-75 years, male or female;
* ECOG score 0-2, life expectancy \> 6 months;
* Patients provide written informed consent.

Exclusion Criteria:

* Contraindications to MRI, such as claustrophobia and metallic or electronic implants incompatible with MRI;
* The presence of severe comorbidities that, in the opinion of the investigator, · preclude the toleration or completion of radiotherapy;
* Acute inflammatory disease requiring systemic therapy;
* The presence of active infectious disease;
* Pregnant women, nursing mothers, and patients planning to have children during the study period.

Where it's running

  • The Second Affiliated Hospital of Hainan Medical University
    Haikou, China
    Recruiting

Study contacts

  • Principal investigator: yuecan zeng, doctor — The Second Affiliated Hospital of Hainan Medical University
  • Study coordinator: junnv xu, doctor
  • Email: xujunnv@sina.com
  • Phone: 18208946196

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.