Condition
PTSD - Post Traumatic Stress Disorder clinical trials and research
As of November 12, 2026, Find a Trial lists 35 PTSD - Post Traumatic Stress Disorder clinical trials that are recruiting, at sites in 12 countries (most in United States (20), Israel (4), Sweden (2)). 2 were first registered in the last 30 days. By phase: Phase 2 (3), Phase 2/3 (2), Phase 3 (2), Phase 1 (1). The most active sponsors are Karolinska Institutet (2), Summit Hyperbarics and Wellness (2), The University of Texas Health Science Center at San Antonio (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 35Clinical trials
- 2New in 30 days
- 12Countries
Newest PTSD - Post Traumatic Stress Disorder clinical trials
All recruiting trials (35)
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Virtual Reality–Assisted Trauma-Focused CBT for PTSD
A VR-assisted trauma-focused CBT approach is being tested to see if it helps adults with PTSD related to Northern Ireland–specific trauma.
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ReVIVE for mTBI: Using VR and therapy to help adults with mild traumatic brain injury
This study tests a virtual reality therapy combined with standard psychotherapy to see if it can reduce PTSD symptoms and improve executive function in adults with mild traumatic brain injury.
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HBOT to see if it helps cognition and well‑being in first responders with prior brain injury
This study tests whether 40 hyperbaric oxygen therapy sessions can improve thinking skills and post-concussion symptoms in current or former first responders with a history of brain injury.
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Predicting nightmare awakenings in PTSD using an AI algorithm
The study tests an AI tool called CAUD-PIN to see if it can reliably predict when trauma-related nightmares will wake military personnel or veterans with PTSD.
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Dexmedetomidine with taVNS to see if PTSD after trauma surgery can be reduced
This study tests whether giving dexmedetomidine together with transcutaneous vagus nerve stimulation after emergency trauma surgery can lower the chances of developing PTSD.
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Early Intervention After Sepsis-ICU to Reduce PTSD
This study tests whether an early psychiatric interview after discharge from the ICU for sepsis can help reduce PTSD and related symptoms.
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Training behavioral health providers to deliver Written Exposure Therapy with web and AI support
This study tests whether web-based training with AI help helps providers learn to deliver Written Exposure Therapy to veterans with PTSD.
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Restory: an online, anonymous trauma therapy for adults affected by sexual abuse
A free, anonymous online therapy program called Restory tests whether it helps reduce PTSD symptoms in adults who experienced sexual abuse, compared with a waitlist control.
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COMP360 psilocybin for PTSD: see if it helps reduce symptoms with guided support
This study tests COMP360 (a lab-made psilocybin) to see if it can help reduce PTSD symptoms in adults, with supervision from a trained team.
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COMP360 psilocybin for PTSD: see if it helps reduce symptoms with guided support
This study tests COMP360 (a lab-made psilocybin) to see if it can help reduce PTSD symptoms in adults, with supervision from a trained team.
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Measuring and reducing patient discomfort during intensive care
This program tests whether a tailored, multi-component feedback program using the IPREA questionnaire can reduce traumatic experiences and later PTSD symptoms for adults discharged after at least three days in intensive care.
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Non-invasive vagus nerve stimulation (gammaCore) for PTSD
This study will test whether the handheld gammaCore device, which delivers mild electrical stimulation to the vagus nerve through the neck, can help adults with PTSD reduce their symptoms.
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Hyperbaric oxygen therapy for post-traumatic stress disorder
This will test whether breathing high-pressure oxygen in a chamber can help adults with PTSD who are eligible for discharge from military service.
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Accelerated brain stimulation for PTSD tailored to your brain map
We’re testing a quick, non-invasive brain treatment to see if it helps adults with PTSD by using MRI-guided targets and multiple daily TMS sessions over 5 days.
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Acceptance- and Mindfulness-Based Exposure Therapy versus Present-Centered Therapy for PTSD after cardiac arrest
This project will test if Acceptance- and Mindfulness-Based Exposure Therapy (AMBET) or Present-Centered Therapy (PCT) better reduces PTSD symptoms in adults who survived a cardiac arrest.
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PTSD-iMPACT: measuring how PTSD affects daily functioning in children and adolescents
This project will test the PTSD-iMPACT questionnaire to measure PTSD-related day-to-day problems in children and adolescents who have experienced trauma.
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Repetitive transcranial magnetic stimulation for veterans with PTSD
It will test whether ten sessions of repetitive transcranial magnetic stimulation (rTMS) over 2–4 weeks can reduce PTSD symptoms in veterans eligible for VA care.
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Senseye iPhone app to test for PTSD
This will test whether the Senseye iPhone app can detect PTSD in adults who are experiencing trauma-related symptoms.
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Hyperbaric oxygen for thinking, mental health, and quality of life in veterans
This trial will try hyperbaric oxygen therapy to see if it improves thinking, PTSD symptoms, mood, anxiety, and overall quality of life in veterans with mild TBI or related conditions.
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New Empowerment After Exposure to Trauma (NEXT) perinatal PTSD program
This project tries a short virtual Narrative Exposure Therapy program to see if it helps pregnant and recently postpartum people with PTSD compared with usual care.
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Early restorative sleep treatment after an emergency department visit
This trial will try virtual cognitive behavioral therapy for insomnia and nightmares soon after an assault-related emergency visit to see if it improves sleep and reduces PTSD symptoms.
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Deciding whether PTSD therapy or tinnitus therapy should come first for people with both conditions.
This project will try giving either PTSD therapy first then tinnitus therapy, or tinnitus therapy first then PTSD therapy, in veterans and active-duty adults with PTSD and bothersome chronic tinnitus to see which order helps more.
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Accelerated 5-day program for insomnia, nightmares, and PTSD
This 5-day group program combines cognitive-behavioral therapy for insomnia and nightmares with written exposure therapy to see if it reduces sleep problems and PTSD symptoms in active-duty military members and veterans who have insomnia, nightmares, and PTSD.
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Narrative Exposure Therapy for Ukrainian refugees in Norway
This project will try Narrative Exposure Therapy delivered by trained Ukrainian health workers to see if it reduces PTSD and depression symptoms in Ukrainian refugees living in Norway.
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5-day intensive trauma-focused program for adolescents with PTSD
This project will try a Swedish 5-day intensive program combining EMDR, trauma-focused CBT elements, physical activity, and caregiver support for adolescents (13–17) with PTSD to see if symptoms improve quickly and more teens complete treatment.
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Using music to improve therapy for PTSD
This study is testing if listening to special music before therapy sessions can help people with PTSD feel better.
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Group Cognitive Processing Therapy for people in prison with PTSD and substance use
This trial tests whether group Cognitive Processing Therapy (CPT) delivered in prison helps adults with PTSD and recent drug problems reduce trauma symptoms, substance use, and re-offending after release.
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Virtual-reality exposure combined with tDCS for PTSD in Ukrainian veterans and civilians
This study will try combining virtual-reality exposure therapy with gentle brain stimulation (tDCS) to see if it helps Ukrainian veterans and civilians with PTSD.
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Trying proven PTSD therapies again or switching approaches when the first treatment doesn't work
This study will test whether offering a second round of proven therapies or switching to a different therapy helps adults with PTSD who did not get better after their first treatment.
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Intensive treatment program for first-time PTSD patients
This study tests whether a five-day intensive treatment program can help adults with first-time PTSD feel better compared to regular weekly sessions.
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Using virtual reality to prepare lung transplant patients for ICU admission
This study tests if using virtual reality can help lung transplant patients feel more prepared and less anxious about their upcoming stay in the ICU.
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Using brain stimulation to reduce intrusive memories in PTSD
This study is testing if brain stimulation can help adults with PTSD reduce unwanted memories and improve their overall symptoms.
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Exploring the effects of MDMA on PTSD in veterans
This study tests whether MDMA-assisted therapy can help military veterans with PTSD feel better by improving their emotional connections and reducing stress.
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Targeted Plasticity Therapy for PTSD
This study is testing whether a new therapy that combines brain stimulation with talk therapy can help people with PTSD feel better.
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A platform for collecting health data on ME/CFS and Long Covid
This study is trying to collect health information from adults with ME/CFS and Long Covid to help researchers better understand these conditions and improve future treatments.
Related topics
Quick answers
How many PTSD - Post Traumatic Stress Disorder clinical trials are recruiting right now?
35, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 12 countries. The most sites are in United States (20 trials), Israel (4 trials), Sweden (2 trials), France (2 trials), Germany (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 3, Phase 2/3: 2, Phase 3: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.