PTSD-iMPACT: measuring how PTSD affects daily functioning in children and adolescents

Development of the PTSD-iMPACT to Measure PTSD-Related Functional Impairment in Children and Adolescents - A Validation Study in Switzerland and Germany

Observational University Children's Hospital, Zurich · NCT07368166

This project will test the PTSD-iMPACT questionnaire to measure PTSD-related day-to-day problems in children and adolescents who have experienced trauma.

Quick facts

Study typeObservational
Enrollment1200 (estimated)
Ages7 Years to 18 Years
SexAll
SponsorUniversity Children's Hospital, Zurich Academic / other
Locations11 sites (Aachen and 10 other locations)
Trial IDNCT07368166 on ClinicalTrials.gov

What this trial studies

The study is a multi-center observational validation of the PTSD-iMPACT conducted in Switzerland and Germany. Development followed two phases: a systematic review that identified gaps in existing instruments, and qualitative interviews and focus groups with trauma-exposed children, adolescents, and caregivers to generate items and domains. The validation will recruit clinical participants (children/adolescents 7–18 and caregivers of children 3–18) and school-based non-clinical samples in Switzerland, using German-language measures and informed consent procedures. Psychometric analyses will examine domain structure, scoring, reliability, and validity across settings.

Who should consider this trial

Good fit: Ideal participants are German-speaking children and adolescents aged 7–18 with trauma exposure and at least moderate PTSS (and caregivers of children aged 3–18 for proxy reports), recruited from participating clinical centers or school samples in Switzerland.

Not a fit: Children outside the specified age ranges, those without sufficient German language skills, individuals not seen at participating sites, or those without required consent are unlikely to benefit directly from this validation.

Why it matters

Potential benefit: If successful, clinicians and researchers will have a validated questionnaire to pinpoint PTSD-related functional problems in young people and better target support and treatment.

How similar studies have performed: While psychometric approaches and adult PTSD functional measures have been successful, a PTSD-specific, validated functional instrument for youth is largely novel with limited prior validation work.

Eligibility criteria

Show full inclusion / exclusion criteria
Clinical population

Inclusion Criteria:

* Use of (mental) health services at a participating study center.
* Children and adolescents between 7 and 18 years / caregivers of children and adolescents between 3 and 18 years
* Sufficient knowledge of the German language
* Signed consent form (7-18 years: patient and caregiver; 3-6 years: caregivers)

Exclusion Criteria:

* Children and adolescents under 7 or over 18 years / caregivers of children and adolescents under 3 or over 18 years
* Not sufficient knowledge of the German language
* No signed consent form (7-18 years: patient and/or caregiver; 3-6 years: caregivers)

Non-clinical population Only recruited in Switzerland.

Inclusion Criteria:

* Students between 3rd grade and 18 years / caregivers of kindergarteners and students up until 18 years
* Sufficient knowledge of the German language

Exclusion Criteria:

* Students 2nd grade or lower and over 18 years / caregivers of children not yet in Kindergarten and students over 18 years
* No sufficient knowledge of the German language

Where this trial is running

Aachen and 10 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions PTSD - Post Traumatic Stress DisorderPTSD-Related Functional Impairment in Children and AdolescentsPTSDPTSSFunctional ImpairmentPTSD-iMPACTValidationPosttraumatic stress disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.