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Prostate Cancer (Diagnosis) clinical trials and research

• 29Clinical trials
• 5NIH research projects
• 2New in 30 days
• 14Countries

Newest Prostate Cancer (Diagnosis) clinical trials

All recruiting trials (29)

• 68Ga-XMFH01 PET/FL imaging to guide prostate cancer surgery

  This study tests a new dual-modality imaging probe, 68Ga-XMFH01, to preoperatively detect prostate cancer and guide the surgeon with fluorescence during operations in adults with newly diagnosed prostate cancer.

  Recruiting The First Affiliated Hospital of Xiamen University · Xiamen, Fujian · NCT07885423

• Hugo Robotic Prostatectomy in an Ambulatory Surgery Center

  This study tests the use of the Hugo robotic system for prostate removal in adult men treated at an outpatient surgical center.

  Recruiting Central Ohio Urology Group · Columbus, Ohio · NCT07875192

• Adaptive intraoperative biopsy system for prostate cancer using imaging and metabolic feedback

  Aiming to test a smart biopsy approach that combines preoperative imaging with real-time metabolic signals to guide where to take prostate biopsy cores for better precision in men suspected of prostate cancer.

  Recruiting at 4 sites Shanghai Zhongshan Hospital · Shanghai and 3 other locations · NCT07856017

• miRNA panel test to help diagnose prostate cancer

  A blood test using a microRNA panel is being tested to help diagnose prostate cancer in men who are suspected of having the disease.

  Recruiting RenJi Hospital · Shanghai · NCT07755592

• Testing 68Ga-NYM032 PET/CT in men with newly diagnosed prostate cancer

  This study tests a new PSMA-targeted PET/CT imaging agent to see if it safely and accurately locates cancer in men who have just been diagnosed with prostate cancer and are planned for surgery.

  Recruiting at 2 sites Phase 3 Norroy Bioscience Co., LTD · Nanjing, Jiangsu and 1 other locations · NCT07615101

• Multi-Modal Imaging and Digital Pathology to Predict Clinically Significant Prostate Cancer

  A multi-center study tests a deep learning model that combines MRI, ultrasound, and digital pathology to see if it can predict clinically significant prostate cancer non-invasively and help guide biopsies.

  Recruiting Guangxi Medical University · Liuzhou, Guangxi · NCT07614256

• TENS to Reduce Pain During Transperineal Prostate Biopsy

  This trial tests whether adding TENS to local anesthesia can lessen pain for men undergoing a transperineal prostate biopsy.

  Recruiting Medical University of Gdansk · Gdansk, Pomeranian Voivodeship · NCT07578324

• Improving Cryoablation for Prostate Cancer with Barrigel Rectal Spacer

  This study tests whether Barrigel, a rectal spacer, can be safely used during prostate cryoablation to help protect surrounding tissues.

  Recruiting NYU Langone Health · New York, New York · NCT07567027

• ACP3-targeted PET/CT imaging to detect prostate cancer lesions

  This will see if ACP3 PET/CT can find more tumor lesions than standard PSMA/FDG PET/CT in adults with prostate cancer or suspected recurrence.

  Recruiting Guilin Medical University, China · Guilin, Guangxi · NCT07559201

• Blood exosomal RNA test to rule out prostate cancer spread to bone

  This project will try a blood-based exosomal RNA test to see if it can rule out bone metastasis in people with newly diagnosed, treatment‑naïve prostate cancer scheduled for baseline PSMA PET.

  Recruiting at 9 sites Xijing Hospital · Lanzhou, Gansu and 8 other locations · NCT07553754

• Using new non-contrast MRI sequences to improve diagnosis and grading of prostate cancer

  This project tries new non-contrast MRI scans to see if they improve diagnosis and grading for men with suspected prostate cancer and elevated PSA.

  Recruiting The First Affiliated Hospital of Soochow University · Suzhou, Jiangsu · NCT07552285

• Early postoperative PSA after prostate removal as a predictor of cancer outcomes

  We will test whether early PSA levels after prostate removal can help predict long-term cancer outcomes in men undergoing radical prostatectomy.

  Recruiting Lithuanian University of Health Sciences · Kaunas, Kauno · NCT07516886

• Epidemiology, diagnosis, and treatment patterns of prostate cancer in Algeria

  This project collects medical and treatment information to see how prostate cancer is diagnosed and managed in Algerian men with confirmed disease.

  Recruiting at 21 sites Société Algérienne de Formation et Recherche en Oncologie · Adrar, Algeria and 23 other locations · NCT07484971

• Targeted plus perilesional biopsy versus targeted plus six‑core systematic biopsy to find prostate cancer

  This study will test whether adding perilesional biopsy to MRI-targeted biopsy or combining targeted biopsy with a six‑core systematic biopsy better finds clinically significant prostate cancer in men with a single MRI-suspicious lesion who have not had a prior biopsy.

  Recruiting Peking University First Hospital · Beijing, Beijing Municipality · NCT07460843

• PROSTest test in men with elevated PSA to aid prostate cancer decisions

  This study tests PROSTest in men with elevated PSA to see if it can accurately detect prostate cancer using biopsy results as the reference.

  Recruiting Wren Laboratories LLC · Branford, Connecticut · NCT07454603

• MRI- and PHI-guided approach to decide when a prostate biopsy is needed

  This trial will test whether using multiparametric MRI together with the Prostate Health Index (PHI) can safely reduce unnecessary prostate biopsies in biopsy-naïve men with suspected prostate cancer and PSA 3–20 ng/mL.

  Recruiting Asan Medical Center · Seoul · NCT07398690

• How prostate MRI lesions change over time with repeated biparametric scans

  This trial will test whether changes seen on repeat biparametric prostate MRI predict clinically significant prostate cancer in men whose initial biopsy showed no significant cancer.

  Recruiting University of Eastern Finland · Kuopio · NCT07369570

• Castration using low-dose abiraterone plus prednisone without LHRH therapy for prostate cancer needing hormonal intensification

  This tests whether taking abiraterone 250 mg with food plus prednisone can lower testosterone to castration levels within 30 days in men with prostate cancer who need hormonal intensification without using LHRH analogs.

  Recruiting at 2 sites Phase 2 SMED Clinical Research · Buenos Aires and 2 other locations · NCT07299292

• Robot-assisted prostate biopsy using a new ultrasound probe

  This trial will try a robot-guided ultrasound probe to take MRI-fused prostate biopsies in men 40–75 with elevated PSA, abnormal rectal exam, or prior atypical biopsy findings.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT07271017

• Virtual biopsy for prostate cancer using PSMA PET and AI

  This project will try to use PSMA PET scans combined with machine learning to predict Gleason scores without invasive biopsies for men with suspected or diagnosed prostate cancer.

  Recruiting University Hospital of North Norway · Tromsø, Troms · NCT07266129

• Digital exercise program with live virtual group sessions for men on hormone therapy during radiotherapy

  This program will test whether a digital exercise program with live virtual group sessions helps men with prostate cancer who are starting or receiving hormone therapy with radiotherapy stick to exercise recommendations and improve health and fatigue.

  Recruiting Royal Marsden NHS Foundation Trust · London · NCT07243834

• Heart-Healthy Cardio-Oncology Check for Prostate Cancer on ARPI Therapy

  This trial tests whether a cardio-oncology referral and shared care between your cardiologist and your primary clinician can help reduce heart-attack and stroke risk in men with advanced prostate cancer who are taking ARPI therapy.

  Recruiting Phase 2 Cedars-Sinai Medical Center · Los Angeles, California · NCT07223385

• Prehabilitation for people with prostate cancer

  This project will test a 12-week multicomponent prehabilitation program, including a 4-day residential course and supervised exercise, to see if it helps men with prostate cancer starting androgen deprivation plus radiation therapy better tolerate treatment side-effects.

  Recruiting at 3 sites Odense University Hospital · Esbjerg, Region Syddanmark and 2 other locations · NCT07162987

• Platelet protein blood test for prostate cancer detection and monitoring

  This study will test whether a blood test that looks at platelet proteins can detect and track prostate cancer in men being checked for the disease.

  Recruiting Duke University · Durham, North Carolina · NCT07144228

• Immune biomarker testing for men receiving prostate brachytherapy

  This project will test how immune cells in blood and tumor tissue change before, during, and after brachytherapy in men treated for prostate cancer.

  Recruiting University of Erlangen-Nürnberg Medical School · Augsburg, Bavaria and 2 other locations · NCT07131956

• Using PSMA PET with MRI to watch for prostate cancer returning after focal therapy

  We will try adding a PSMA PET scan to routine MRI follow-up to see if it finds prostate cancer coming back sooner in men who had focal (partial gland) therapy.

  Recruiting University of Chicago · Chicago, Illinois · NCT07115914

• Comparing Lutetium-177 and Actinium-225 PSMA-targeted radiation before prostatectomy

  This will test whether giving one of two PSMA-targeted radiation drugs (Lutetium-177 or Actinium-225) before prostate removal works differently in men with high or very high-risk localized prostate cancer.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT07054346

• Evaluating a Virtual Oncology Program for Veterans with Cancer

  This study is testing a virtual cancer care program for veterans to see if it helps them get better treatment and support for lung, colorectal, prostate, and breast cancers.

  Recruiting at 5 sites NYU Langone Health · Brooklyn, New York and 4 other locations · NCT06559059

• Comparing needle sizes for better prostate cancer detection

  This study tests whether using a bigger needle for prostate biopsies helps find cancer better than using a smaller needle for men who might have prostate cancer.

  Recruiting University Hospital Padova · Padua, Italy · NCT06420115

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Ethical multimodal AI platform to improve prostate cancer detection with ultrasound

  A patient-friendly AI system uses ultrasound and MRI information to help doctors better find prostate cancer, aiming to improve accuracy and access.

  NIH research Stanford University · Stanford, United States · NIH-11596787

• Targeting PSMA for Prostate Cancer Diagnosis and Treatment

  This project explores a new way to find and treat advanced prostate cancer by focusing on a specific protein called PSMA.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11114031

• Using advanced digital imaging and AI to improve prostate cancer diagnosis

  This study is working on using advanced computer technology to help doctors better understand prostate cancer by analyzing tissue samples, making it easier to spot tumors and explain the results clearly.

  NIH research University of California-Irvine · Irvine, United States · NIH-10990125

• Improving prostate cancer diagnosis using advanced ultrasound techniques

  This study is testing a new type of ultrasound to help doctors find serious prostate cancer more accurately and affordably, so patients can get the right treatment without unnecessary procedures for less aggressive cases.

  NIH research Thomas Jefferson University · Philadelphia, United States · NIH-10910108

• Investigating a new target for diagnosing and treating prostate cancer

  This study is looking at how a specific protein called PSMA affects prostate cancer, especially when it becomes harder to treat after hormone therapy, and aims to create new personalized treatments and better ways to diagnose and track the disease for patients.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-10877944

Related topics

Quick answers

How many Prostate Cancer (Diagnosis) clinical trials are recruiting right now?

29, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in United States (9 trials), China (9 trials), Finland (1 trial), Poland (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 1: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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