Using advanced digital imaging and AI to improve prostate cancer diagnosis

Virtual Digital Histopathology with Explainable Deep Learning for Prostate Cancer Diagnosis

NIH-funded research University of California-Irvine · NIH-10990125

This study is working on using advanced computer technology to help doctors better understand prostate cancer by analyzing tissue samples, making it easier to spot tumors and explain the results clearly.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine NIH-funded
Lab location1 site (Irvine, United States)
Project IDNIH-10990125 on NIH RePORTER

What this research studies

This research focuses on enhancing prostate cancer diagnosis through the use of digital histopathology and deep learning algorithms. By analyzing tissue biopsy images, the project aims to automate tumor segmentation and provide clearer explanations of the results to clinicians. The approach involves converting non-stained biopsy images into virtual stained versions, allowing for better evaluation of tumor characteristics and aiding in accurate diagnosis. The goal is to improve the interpretability of these advanced imaging techniques for better clinical adoption.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals undergoing prostate biopsies for suspected cancer.

Not a fit: Patients who have already been diagnosed and treated for prostate cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and reliable prostate cancer diagnoses, ultimately improving patient outcomes.

How similar studies have performed: Previous research has shown promise in using deep learning for cancer diagnosis, indicating potential success for this novel approach.

Where this research is happening

Irvine, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.