Improving prostate cancer diagnosis using advanced ultrasound techniques
Official title: Prostate Cancer Diagnosis by Multiparametric Ultrasound
Funded at Thomas Jefferson University · NIH-10910108 · Data updated 2026-11-12
This study is testing a new type of ultrasound to help doctors find serious prostate cancer more accurately and affordably, so patients can get the right treatment without unnecessary procedures for less aggressive cases.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thomas Jefferson University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | July 1, 2020 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $562,920 |
| NIH project number | 5R01CA252311-05 |
| Project ID | NIH-10910108 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men who are at risk for prostate cancer and may require diagnostic imaging to determine the aggressiveness of their condition.
✕Less likely to help
Patients with low-risk prostate cancer who do not require further diagnostic intervention may not benefit from this research.
What this research studies
This research focuses on enhancing the diagnosis of prostate cancer by utilizing advanced ultrasound methods, specifically contrast-enhanced ultrasound (CEUS). The goal is to identify clinically significant prostate cancer more accurately and cost-effectively than current methods, such as multiparametric MRI. By employing innovative imaging techniques like subharmonic imaging and dispersion imaging, the research aims to reduce the number of missed aggressive cancer cases and minimize unnecessary treatments for non-aggressive cancers. Patients will undergo ultrasound imaging to assess the presence of significant prostate cancer lesions.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and less invasive prostate cancer diagnoses, reducing overtreatment and improving patient outcomes.
How similar studies have gone: Previous studies have shown promise in using advanced ultrasound techniques for cancer detection, indicating that this approach may lead to significant advancements in prostate cancer diagnosis.
Where this research is happening
-
Thomas Jefferson University
Philadelphia, United States Active
Researchers
- Principal investigator: Forsberg, Flemming — Thomas Jefferson University
- Study coordinator: Forsberg, Flemming
Related research
Other NIH-funded projects on the same topics.
-
Ethical multimodal AI platform to improve prostate cancer detection with ultrasound
A patient-friendly AI system uses ultrasound and MRI information to help doctors better find prostate cancer, aiming to improve accuracy and access.
-
Real-time AI-assisted ultrasound guides for targeted prostate biopsies
A new AI-powered tool uses conventional and micro-ultrasound to help clinicians target suspicious prostate areas during ultrasound-only biopsies, aiming to improve cancer detection for men who need biopsy.
-
Nanoparticle ultrasound to help find prostate cancer during biopsy
This project develops tiny, prostate-specific ultrasound bubbles to help doctors see cancer during transrectal prostate biopsies in men with suspected prostate cancer.
-
Dual-modality ultrasound and photoacoustic imaging to improve prostate cancer detection
A new imaging approach combines ultrasound and light-based imaging to better identify aggressive prostate cancer in American men.
-
Targeting PSMA for Prostate Cancer Diagnosis and Treatment
This project explores a new way to find and treat advanced prostate cancer by focusing on a specific protein called PSMA.
-
Using advanced digital imaging and AI to improve prostate cancer diagnosis
This study is working on using advanced computer technology to help doctors better understand prostate cancer by analyzing tissue samples, making it easier to spot tumors and explain the results clearly.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.