Condition

Osteopenia clinical trials and research

• 10Clinical trials
• 2NIH research projects
• 8Countries

Newest Osteopenia clinical trials

All recruiting trials (10)

• Functional Muscle-Bone Incongruity Index: A look at muscle strength and bone health in adults

  This observational study tests a composite FKUI score using handgrip strength and hip/spine bone density to see if it better reflects musculoskeletal health than each measure alone in adults undergoing routine DXA.

  Recruiting Kanuni Sultan Suleyman Training and Research Hospital · Küçükçekmece, Istanbul · NCT07677033

• Veverimer to reduce acid load and slow bone loss in adults with osteopenia

  This trial will test whether taking veverimer, compared with placebo, lowers urinary acid levels and reduces bone breakdown in adults aged 50 and older with osteopenia.

  Recruiting Phase 1 Tufts Medical Center · Boston, Massachusetts · NCT07473713

• Using REMS ultrasound to check bone density in children and teens with conditions that lower bone strength

  This project will test whether REMS, a radiation-free ultrasound method, can measure bone mineral density in children and adolescents aged 5–18 who have conditions that weaken their bones.

  Recruiting Meyer Children's Hospital IRCCS · Florence, Tuscany · NCT07412782

• Weekly everolimus and resistance training to boost bone health in postmenopausal women

  This project will see if a weekly everolimus pill, resistance (strength) training, or both can improve bone formation and muscle function in postmenopausal women aged 60–75.

  Recruiting at 2 sites Phase 2 Odense University Hospital · Bispebjerg, Region Sjælland and 1 other locations · NCT07191353

• Validating lab assays, IV catheter techniques, and devices for endocrine, cardiometabolic, and musculoskeletal conditions

  This project will test whether laboratory assays, IV catheter methods, and equipment give consistent, reliable results in adults with or without obesity-related, metabolic, or musculoskeletal conditions.

  Recruiting University of Missouri-Columbia · Columbia, Missouri · NCT07083557

• High-Intensity Interval Training for Bone Health in Older Women

  This study is testing if a 24-week high-intensity workout program can help older women with low bone density feel better and improve their bone health.

  Recruiting Hong Kong Baptist University · China, Hong Kong · NCT06888544

• Vitamin K2 supplementation for patients with low bone density and a specific gene variant

  This study is testing if taking vitamin K2 can help improve bone density in adults aged 40-75 with low bone density who have a specific gene variant.

  Recruiting S.lab (Soloways) · Novosibirsk · NCT06867952

• Preventing bone loss in HIV positive individuals using zoledronic acid

  This study tests if a single dose of zoledronic acid can help prevent bone loss in people who have just been diagnosed with HIV and are starting treatment.

  Recruiting Phase 4 Hadassah Medical Organization · Haifa and 2 other locations · NCT06762730

• Manual therapy for low back pain in postmenopausal women with osteopenia

  This study is testing if manual therapy can help relieve low back pain in postmenopausal women with osteopenia.

  Recruiting Cairo University · Giza · NCT06671665

• Using blood cells to improve osteoporosis diagnosis and monitoring

  This study is testing if checking the health of certain blood cells can help doctors better diagnose and monitor osteoporosis in both men and women.

  Recruiting at 2 sites Istituto Ortopedico Rizzoli · Bologna and 1 other locations · NCT06551155

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Veverimer to reduce acid in diet-related bone loss in adults with osteopenia

  A medication called veverimer is being tested in adults with osteopenia to see if it helps reduce bone loss by neutralizing excess acid from the diet without causing extra sodium or potassium problems.

  NIH research Tufts Medical Center · Boston, United States · NIH-11384241

• How oxidative stress affects bone health in people who drink alcohol.

  This study looks at how drinking alcohol affects bone health by exploring the role of oxidative stress, and it's for people who want to understand how their alcohol use might lead to weaker bones.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11115773

Related topics

Quick answers

How many Osteopenia clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in Italy (2 trials), United States (2 trials), Russia (1 trial), China (1 trial), Israel (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 2: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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