High-Intensity Interval Training for Bone Health in Older Women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of a 24-week high-intensity interval training (HIIT) program on bone health in older women diagnosed with osteopenia. Participants aged 60 to 74 will be randomly assigned to either the HIIT intervention or a non-exercise control group. The study will measure outcomes such as bone mineral density, bone turnover markers, physical fitness, fear of falling, and quality of life at baseline, post-intervention, and six months later. The aim is to determine if HIIT can improve bone health and overall well-being in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* • 60 to 74 years at the start date of the project

  * diagnosed with osteopenia by DXA scan screening with a BMD at the femoral neck or total hip or lumbar spine between -1 and -2.5 SD T-score below the average values
  * Passing the PAR-Q plus screening or with the physician's approval for readiness to participate in high-intensity exercise
  * Above the average level of 2-mins stepping showing competent aerobic fitness
  * No restriction on physical mobility
  * No cognitive impairment, as determined by the Chinese version of the Mini-Mental Status Examination (i.e., score \< 24)
  * No previous substantial experiences in practicing HIIT. The written informed consent form will be collected from each participant

Exclusion Criteria:

* • Severe chronic disease restricting high-intensity exercise

  * Having cognition impairment regarded by specialists
  * checked through medical records at HA Go app platform in the past 6 months, have concurrent medical conditions (e.g., thyrotoxicosis or hyperparathyroidism, Paget's disease, renal disease, diabetes, knee or hip osteoarthritis) and use medications (e.g., corticosteroids, estrogen, thyroxine, thiazide diuretics, or antiretroviral agents) known to affect bone metabolism during past 2 years
  * any condition with osteoporosis, osteoporotic fractures
  * current smoker
  * alcohol 3 or more units per day.

Where it's running

• Bliss District Elderly Community Centre
  China, Hong Kong, China Recruiting

Study contacts

• Principal investigator: Yanping Duan — Hong Kong Baptist University; Department of Sport, Physical Education and Health
• Study coordinator: Yanping Duan
• Email: duanyp@hkbu.edu.hk
• Phone: 34115638

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.