Home › Trials › NCT07083557
Clinical trial Recruiting at 1 site Observational Ages 18 to 100

Validating lab assays, IV catheter techniques, and devices for endocrine, cardiometabolic, and musculoskeletal conditions

Official title: Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

Run by University of Missouri-Columbia · NCT07083557 · Data updated 2026-11-12

This project will test whether laboratory assays, IV catheter methods, and equipment give consistent, reliable results in adults with or without obesity-related, metabolic, or musculoskeletal conditions.

Quick facts

Study typeObservational
Ages18 Years to 100 Years
SexAll
Enrollment100 (estimated)
SponsorUniversity of Missouri-Columbia
Academic / other
Locations1 site (Columbia, Missouri)
StatusRecruiting
StartedJanuary 1, 2027
Main results expectedJuly 1, 2030
Study endsJuly 1, 2030
Registry record updatedMay 7, 2026
Trial IDNCT07083557 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–100 with a body mass index between 16.0 and 60 kg/m2 who are healthy or have relevant endocrine, cardiometabolic, or musculoskeletal conditions and who are not taking medications or supplements that interfere with the tested assays may qualify.

Probably not a fit

People who are pregnant, current smokers, prisoners, use interfering medications or supplements, have significant organ dysfunction (unless sought for validation), or cannot attend in-person procedures are unlikely to receive benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project compares results from current and new laboratory assays, intravenous catheter insertions, and equipment to determine reproducibility. Participants who are healthy or who have obesity, diabetes, atherosclerotic disease, heart failure, or MASH will undergo repeated measurements to see if the same results are achieved each time. Procedures may include blood draws, endothelial cell collection, standardized meals, and use of different devices or assays, with exclusions for medications, diets, or behaviors that could interfere. The work is conducted at the University of Missouri-Columbia to ensure accurate, repeatable testing for chronic disease and metabolism research.

Why it matters

Potential benefit: If successful, this work will increase confidence that lab tests and techniques produce accurate, repeatable results, improving the quality of research and supporting better clinical decisions.

How similar studies have gone: Similar validation and reproducibility efforts are common and have confirmed reliability for many established assays, although newer devices and methods often require fresh testing.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* ≥18 and ≤100 years of age
* body mass index ≥16.0 and ≤60 kg/m2

Exclusion Criteria:

* \<18 and \>100 years of age
* body mass index \<16.0 or \>60 kg/m2
* allergies, intolerances, or dietary restrictions to meal ingredients, vegans or vegetarians
* use of medications or dietary supplements (e.g., anti-inflammatories, immune modulators, etc) that could interfere with the particular assay/techniques being evaluated
* engaged in regular structured exercise \>150 min per week unless needed for validation of the assay/technique being evaluated
* significant organ system dysfunction or diseases, except those that are sought for validation of the assay/technique being evaluated
* alcohol use disorder as defined by the National Institute of Alcohol Abuse and Alcoholism or use of controlled substances unless alcohol use disorder is required for validation of the assay/technique being evaluated
* pregnant women, persons who smoke, prisoners, and inability to grant voluntary informed consent.

Where it's running

  • University of Missouri-Columbia
    Columbia, Missouri, United States     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov ↗ Find more trials like this →
Browse more
Obesity and Obesity-related Medical Conditions 21Diabetes 1647Atherosclerotic Disease 2Heart Failure 1020MASH 9Sarcopenia 155Osteoporosis 125Hyperparathyroidism 8Hypoparathyroidism 20Ischemic Heart Disease 59Cystic Fibrosis (CF) 36Chronic Kidney Disease(CKD) 24
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.