Investigating how carbonated water affects blood pressure when standing

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This investigation aims to determine if drinking carbonated water can enhance orthostatic tolerance in healthy volunteers. Orthostatic tolerance is the ability to maintain blood pressure while standing, which can be compromised in some individuals, leading to dizziness or fainting. The study will involve 25 volunteers undergoing a tilt test to measure their cardiovascular response and time to presyncope after consuming carbonated and non-carbonated water. The hypothesis is that carbonated water may provoke gastric distension, increasing sympathetic activity and thereby boosting blood pressure more than still water.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* healthy, English-speaking

Exclusion Criteria:

* pregnancy or suspected pregnancy, history of cardiovascular disease, history of neurological disease, history of recurrent fainting (≥ 2 episodes of fainting with loss of consciousness in the prior 6 months)

Where it's running

• Simon Fraser University
  Burnaby, British Columbia, Canada Recruiting

Study contacts

• Principal investigator: Victoria E Claydon, PhD — Professor, Biomedical Physiology and Kinesiology
• Study coordinator: Victoria E Claydon, PhD
• Email: victoria_claydon@sfu.ca
• Phone: 7787828513

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.