Condition
Older Adults (65 Years and Older) clinical trials and research
As of November 12, 2026, Find a Trial lists 21 Older Adults (65 Years and Older) clinical trials that are recruiting, at sites in 13 countries (most in United States (6), Belgium (3), Turkey (Türkiye) (2)). By phase: Phase 2 (1), Phase 4 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 21Clinical trials
- 13Countries
Newest Older Adults (65 Years and Older) clinical trials
All recruiting trials (21)
-
Influenza Vaccine Immunogenicity in Older Adults with Repeated Vaccination
This study tests how different flu vaccines perform in adults 65+ who get yearly vaccines to see if age and repeated vaccination affect the immune response.
-
Seeing the world from home: using virtual reality travel to help lonely older adults
A small pilot study will test whether virtual reality travel experiences can help reduce loneliness in people aged 65 and older who are open to trying VR.
-
eCardiacRehab: a home-based, patient-centered cardiac rehab program
This trial tests a hybrid home-based cardiac rehabilitation program to see if it reduces cardiovascular deaths and ED visits while improving quality of life for adults with CAD after PCI, compared with usual care.
-
Short versus long intermittent hypoxic-hyperoxic training for people with type 2 diabetes, including older adults
This study will see if short (3-day) or longer (10-day) sessions of intermittent low-oxygen/high-oxygen breathing improve blood sugar control in people aged 50–74 with type 2 diabetes.
-
Promoting Walking for Older Adults with Friendly Messages and Step Reminders
This study tests whether friendly affective messages and step-tracking reminders can help adults aged 65–74 walk more, by linking memories of their past selves to their present and future actions.
-
How short power-training sessions affect muscle power and movement in older adults.
This test will try three leg-press power-training sessions with different fatigue levels to see which approach is safest and most helpful for adults aged 65–85.
-
Predictors of climate change health literacy in people 65 and older
This project tries to see which factors are linked to how well adults 65 and older understand climate change and its effects on health.
-
Breathing exercises added to balance training to support thinking and prevent falls in older adults
This program will test whether adding specific breathing exercises to twice-weekly balance training helps thinking skills in adults 65 and older.
-
Personalized exercise prescription for adults 65 and older
This project will try a personalized exercise prescription delivered in primary care to see if it helps sedentary adults aged 65 and older improve fitness, muscle strength, and quality of life.
-
Pilot randomized test of a social network program for older adults with advanced cancer
This pilot will try the SONATA social network program to see if it helps adults 65 and older with advanced cancer manage their care better and improve quality of life.
-
Zinc supplementation in older medical patients to see if days alive and out of hospital improve
Giving 22 mg of zinc once daily for 12 months to older medical patients in the ED is being tested to see if it helps more days alive and out of the hospital compared with not giving zinc.
-
Tackling Muscle Loss in Hospitalized Older Adults with Blood Flow Restriction and a Gamified Muscle Check
In this study, older adults who are in the hospital and at risk of losing muscle strength will try a light, safe exercise program paired with blood flow restriction and driven by a tablet game to see if it preserves strength during hospitalization.
-
Integrated care for older adults with major depression and multiple chronic conditions
This program will test whether a coordinated, person-centered care approach called I-CONNECT helps older adults (65+) with depression or bipolar disorder and at least two long-term physical illnesses feel better and manage their care more easily.
-
Virtual reality to enhance behavioral activation for depression in older adults
This trial will try using a VR headset alongside behavioral activation therapy to help people aged 65 and older who have major depressive disorder.
-
Digital home-based program to boost activity after hip replacement in older adults
This trial will test whether a 12-week tablet exercise program, with or without personal coaching, helps adults 65+ increase physical activity after total hip replacement.
-
Physical fitness and executive thinking in adults 65 and older over one year
This project will test whether changes in physical fitness over one year are linked to thinking skills and emotional-control in people aged 65 and older.
-
Using physical tests to improve discharge planning for older adults
This study tests if simple physical tests can help doctors and therapists make better plans for older adults leaving the hospital.
-
CBT-I for insomnia in older African American adults
This project will try an eight-session online CBT-I program to see if it helps older African American adults who have chronic insomnia.
-
Improving care transitions after colorectal surgery for older adults
This study will test whether a coordinated care transition program helps people 65 and older recover better and avoid being readmitted after elective colorectal surgery.
-
Study on physical and cognitive aging in older Hispanic adults
This study is trying to see how physical activity and thinking skills change over time in older Hispanic adults to understand aging better.
-
Using blood pressure and oxygen measurements to predict fall risk in older adults
This study is trying to see if measuring blood pressure and oxygen levels can help predict fall risks in older adults who have fallen in the past year.
Related topics
Quick answers
How many Older Adults (65 Years and Older) clinical trials are recruiting right now?
21, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 13 countries. The most sites are in United States (6 trials), Belgium (3 trials), Turkey (Türkiye) (2 trials), Netherlands (1 trial), Norway (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.