Physical fitness and executive thinking in adults 65 and older over one year
Official title: Changes in Health-related Physical Fitness on the Behavioural and Electrophysiological Aspects of Cool and Hot Executive Function in Older Adults: A Prospective Study
Run by National Taiwan Normal University · NCT07048561 · Data updated 2026-11-12
This project will test whether changes in physical fitness over one year are linked to thinking skills and emotional-control in people aged 65 and older.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | National Taiwan Normal University Academic / other |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | June 1, 2025 |
| Main results expected | March 31, 2027 |
| Study ends | March 31, 2027 |
| Registry record updated | July 2, 2025 |
| Trial ID | NCT07048561 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are community-dwelling adults aged 65 or older who can complete fitness testing and have normal or corrected-to-normal vision.
✕Probably not a fit
People with cardiopulmonary disease, diagnosed cognitive, neurological or psychiatric disorders, certain infectious diseases, active substance abuse, color vision deficiency, a family history of aneurysm, or taking medications that affect brain function are excluded and unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective one-year observational study will recruit 200 adults aged 65 or older and perform baseline and one-year follow-up testing. Physical fitness assessments include cardiorespiratory endurance (YMCA submaximal cycle test), muscular strength (grip, chest press, leg press), muscular endurance (30-second chair stand, 30-second bicep curl), flexibility, and balance (Balance Error Scoring System). Executive function is measured with the Stroop and emotional Stroop tasks while recording EEG to capture event-related potentials, and demographic and covariate data are collected. No intervention is provided; the analysis will test whether within-person changes in fitness predict changes in behavioral and electrophysiological markers of cool and hot executive function.
Why it matters
Potential benefit: If successful, the findings could point to which fitness components help preserve thinking and emotional-control skills in older adults, informing prevention and exercise guidance.
How similar studies have gone: Prior work has associated cardiorespiratory fitness and strength with better executive function, but few studies have simultaneously tracked multiple fitness domains alongside EEG/ERPs over time, making this approach partly novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 65 or above. * Able to engage in fitness testing. * Normal vision or corrected-to-normal vision. Exclusion Criteria: * Suffering from cardiopulmonary-related diseases. * Suffering from cognitive, neurological or psychiatric disorders (e.g., dementia, Parkinson's disease, epilepsy, depression, schizophrenia, etc.). * Suffering from infectious diseases (e.g., hepatitis, human immunodeficiency virus or Creutzfeldt-Jakob disease). * Having a history of drug or alcohol abuse. * Having colour vision deficiency (e.g., colour blindness). * Having a family history of aneurysm. * Taking medications that affect brain function.
Where it's running
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National Taiwan Normal University
Taipei, Taiwan Recruiting
Study contacts
- Principal investigator: Ruei-Hong Li, MS — National Taiwan Normal University
- Study coordinator: Ruei-Hong Li, MS
- Email: rueihongli@gmail.com
- Phone: +886-988163220
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.