Clinical trial Recruiting at 1 site Interventional Ages 65 to 85

How short power-training sessions affect muscle power and movement in older adults.

Official title: Acute Neuromuscular and Physiological Responses to Different Velocity Loss Thresholds During Power Training in Older Adults

Run by Hasselt University · NCT07522398 · Data updated 2026-11-12

This test will try three leg-press power-training sessions with different fatigue levels to see which approach is safest and most helpful for adults aged 65–85.

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Quick facts

Study typeInterventional
Ages65 Years to 85 Years
SexAll
Enrollment42 (estimated)
SponsorHasselt University
Academic / other
Locations1 site (Diepenbeek, Flanders)
StatusRecruiting
StartedApril 20, 2026
Main results expectedJanuary 2027
Study endsJanuary 2027
Registry record updatedSeptember 17, 2026
Trial IDNCT07522398 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Healthy, independently living adults aged 65–85 who have not regularly done resistance training in the past year and who have physician clearance for exercise are ideal candidates.

Probably not a fit

Those with unstable heart or neurological disease, acute infection, recent lower-limb injury or joint replacement, or recent use of NSAIDs or certain supplements may be excluded and unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Healthy adults aged 65 to 85 will complete three supervised power-training sessions on a pneumatic leg press about one week apart, with each session designed to produce a different level of fatigue. Researchers will measure acute changes in strength, movement, and neuromuscular function before and after each session, and will track recovery, muscle soreness, and perceived exertion. Participants will not need prior resistance training experience and will be screened for cardiovascular and musculoskeletal safety. The crossover design lets each participant serve as their own control to compare immediate responses to varying fatigue targets.

Why it matters

Potential benefit: If successful, the findings could guide safer and more effective power-training plans that improve leg power and mobility while minimizing soreness or overfatigue in older adults.

How similar studies have gone: Previous research shows power training can improve strength and mobility in older adults, but acute comparisons of different fatigue levels during power training are less well established.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria:

Participants must:

* Be 65 to 85 years old.
* Be able to live independently and perform everyday activities without help.
* Not have regularly done resistance or strength training in the past year.
* Be able to understand study instructions and communicate in the study language.
* Have a recent statement from their treating physician confirming that their heart and blood vessels are healthy enough to safely take part in this study.

Exclusion criteria

Participants will not be eligible if they have any of the following:

* Unstable heart disease, neurological disease, acute infection, or fever.
* Use of non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, in the 5 days before the study.
* Use of whey protein, casein, or amino acid supplements in the month before the study.
* Acute or chronic injuries to the legs or lower body muscles.
* Any injury or condition that prevents safe leg extension exercises.
* Recent lower-limb joint replacement (less than 6 months ago).
* Dependence on walking aids.
* Current participation in another interventional trial.

Where it's running

  • REVAL - Faculty of Rehabilitation Sciences
    Diepenbeek, Flanders, Belgium
    Recruiting

Study contacts

  • Principal investigator: Evelien Van Roie, PhD — Hasselt University, Faculty of Rehabilitation Sciences
  • Study coordinator: Max Riesbeck, Master of Science
  • Email: max.riesbeck@uhasselt.be
  • Phone: +32 11 26 84 93

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.