Condition

Obesity Prevention clinical trials and research

• 15Clinical trials
• 25NIH research projects
• 11Countries

Newest Obesity Prevention clinical trials

All recruiting trials (15)

• Validating measurements of how much energy your body uses

  This study tests whether measuring energy expenditure in a whole-room calorimeter gives healthy adults a more accurate guide to how much to eat to keep their weight stable.

  Recruiting University of Leipzig · Leipzig, Saxony · NCT07155564

• BETTER4All personalized weight-management pilot

  This pilot tests whether a personalized smartphone app plus a smartwatch using AI can monitor daily behaviors and support weight management for adults aged 18–65.

  Recruiting at 7 sites Harokopio University · Nicosia and 6 other locations · NCT07120802

• Improving team-based biopsychosocial training so clinics can deliver recommended obesity care

  This project will test two training methods to help clinic teams (primary care clinicians, behavioral health staff, dietitians, and community health workers) deliver USPSTF-recommended obesity care to patients at Federally Qualified Health Centers.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT07049861

• Hands-on nutrition demonstrations added to the Diabetes Prevention Program for people with prediabetes

  This project will test whether adding a 7-week series of healthy cooking and nutrition demos to the Diabetes Prevention Program helps adults at risk for prediabetes stay engaged and put healthy eating into daily life.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06897982

• Dairy intake and metabolic health in teens and older adults

  This project will test whether eating three servings of dairy each day helps overweight or obese teens (15–18) and older adults (60–80) improve weight, body composition, and metabolic health over six months.

  Recruiting University of Toronto · Toronto, Ontario and 1 other locations · NCT06879652

• Preventing obesity in American Indian 4th graders at rural tribal schools

  This project will test whether a culturally relevant health and activity curriculum can help prevent obesity in 4th grade American Indian students at rural tribal schools.

  Recruiting Northern Arizona University · Flagstaff, Arizona and 2 other locations · NCT06864468

• Calorie-reduced Mediterranean diet plus activity program to lower chronic disease risk in 30–50-year-olds

  This program will try a 25% calorie-reduced Mediterranean diet combined with increased physical activity to help 30–50-year-olds with metabolic syndrome lose weight and improve cardiometabolic health.

  Recruiting IMDEA Food · Madrid, Madrid · NCT06857929

• Observational study on obesity prevention in Louisiana families

  This study follows Louisiana families to see how different habits and programs can help prevent obesity in children over time.

  Recruiting Pennington Biomedical Research Center · Baton Rouge, Louisiana · NCT06849206

• HealthyW8 for people aged 60 and older

  This 3-month pilot will test a smartphone app that gives personalized healthy-lifestyle recommendations to see if people aged 60+ in Luxembourg will use it and improve their diet and physical activity.

  Recruiting Luxembourg Institute of Health · Luxembourg · NCT06816147

• Tirzepatide effects on muscle and blood-vessel health in older adults with obesity

  This trial will try tirzepatide for six months in adults 50 and older with obesity but without diabetes to see if it changes muscle mass, strength, and blood vessel health.

  Recruiting Phase 2 The University of Texas Health Science Center at San Antonio · San Antonio, Texas · NCT06811324

• Behavioral sleep intervention for preventing obesity in children

  This study is testing whether helping children aged 6-11 from lower-income families improve their sleep with personal coaching or educational materials can prevent obesity.

  Recruiting Temple University · Philadelphia, Pennsylvania · NCT06810557

• Optimizing extended care to help people keep weight off

  This program will test which combination of four low‑burden supports helps adults with obesity who have lost weight keep that weight off.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT06785064

• Gastric ablation therapy for weight management after stopping GLP-1 medications

  This study tests if a procedure called gastric ablation can help adults keep off weight they lost with GLP-1 medications after they stop taking them.

  Recruiting True You Weight Loss · Cary, North Carolina and 1 other locations · NCT06734312

• Community-based hydration intervention in schools

  This study is testing a program in schools to see if adding water stations helps students drink more water, stay healthier, and improve their overall well-being.

  Recruiting Virginia Commonwealth University · Henrico, Virginia · NCT06714929

• A family fitness program for Latino families on the U.S.–Mexico border

  This study tests whether a 12-month family-centered physical activity program can help Latino parents and their 6–11 year-old children near the U.S.–Mexico border become more active and fit.

  Recruiting San Diego State University · San Diego, California · NCT06596902

NIH-funded research (25)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Helping communities use proven obesity-prevention ideas for kids

  A study will test network-based approaches to help coalitions that serve underserved communities adopt proven obesity-prevention strategies for children.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11598101

• GrowSmart: A kid-friendly AI tool to help primary care teams prevent obesity

  A pediatric primary care tool using artificial intelligence helps identify kids at risk for obesity and supports doctors and families in choosing healthy lifestyle steps.

  NIH research Nemours Children's Hospital, Delaware · Wilmington, United States · NIH-11449950

• Strategies to boost impact of an obesity prevention program in communities

  A project will test how to scale and optimize HEALTH, a proven weight-management program for young adult women, in real community settings.

  NIH research Washington University · Saint Louis, United States · NIH-11449567

• Community-driven Infant Obesity Prevention: Supporting Healthy Feeding by Addressing Moms’ Mental Health

  A community-informed program helps low-income families with infants develop healthy eating and feeding habits early, while supporting mothers’ mental health.

  NIH research University of Cincinnati · Cincinnati, United States · NIH-11400735

• Obesity Prevention Targets for Down Syndrome

  A study to find early, practical ways to prevent overweight and obesity in children and adults with Down syndrome.

  NIH research Colorado State University · Fort Collins, United States · NIH-11385544

• Mobile sleep-boosting tool to help kids stay slim

  A mobile health platform is being developed to help children 0-11 sleep better at home, with the aim of preventing obesity.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11376522

• FF+: A family program to prevent obesity in first-time military parents and their babies

  A family-based program delivered around birth helps first-time military parents build coparenting and healthy family habits to prevent obesity in their infants and reduce moms’ postpartum weight gain.

  NIH research Pennsylvania State University, the · University Park, United States · NIH-11335756

• Adaptive approach to spread obesity-prevention practices in early education

  A program to help preschool meals and snacks improve kids' diets in early care settings using practical, supported steps for teachers and staff.

  NIH research Univ of Arkansas for Med Scis · Little Rock, United States · NIH-11293133

• Parenting approaches to prevent obesity in very food-motivated young children

  This project looks at different ways parents feed and manage meals to help prevent unhealthy weight gain in preschool children who are strongly motivated by food.

  NIH research Temple Univ of the Commonwealth · Philadelphia, United States · NIH-11247541

• Improving healthy eating and obesity prevention in early childcare

  This project tries a stepwise approach to help childcare centers use a proven healthy-eating program so young children eat better and keep a healthier weight.

  NIH research Univ of Arkansas for Med Scis · Little Rock, United States · NIH-11195551

• Childhood Obesity Prevention Center

  This center works to develop and test ways to prevent and reduce obesity in children and teens, especially in Arkansas.

  NIH research Arkansas Children's Hospital Res Inst · Little Rock, United States · NIH-11193873

• Preventing excess weight in young children with Down syndrome

  This project will test ways to prevent excess weight in young children with Down syndrome by tracking their growth, eating, activity, and sleep.

  NIH research Colorado State University · Fort Collins, United States · NIH-11176816

• Helping military parents promote healthy lifestyles for their infants

  This study is testing a friendly program called Family Foundations Plus to help first-time military parents create a healthier lifestyle for themselves and their babies, focusing on teamwork and support before and after their child is born.

  NIH research Pennsylvania State University, the · University Park, United States · NIH-11126787

• Better Sleep for Children to Prevent Obesity Using a Mobile App

  This project aims to create and improve a mobile app that helps children sleep longer to prevent childhood obesity.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11124204

• A new program to prevent obesity in high-risk infants during primary care visits

  This study is testing a new program to help families with high-risk infants, especially those from Black, Hispanic/Latinx, and low-income backgrounds, learn how to promote healthy growth and eating habits to prevent obesity right from the start.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11085233

• Improving school policies to prevent childhood obesity and support heart health

  This study is looking at how to make it easier for schools to provide healthy meals and programs to help prevent obesity and heart disease in kids, especially those from low-income and minority families, so that more children can enjoy better nutrition and do better in school.

  NIH research Temple Univ of the Commonwealth · Philadelphia, United States · NIH-11019712

• Understanding how to help parents prevent obesity in highly food motivated children

  This study is looking at helpful parenting tips to keep young kids who love food from becoming overweight, especially for families from low-income racial and ethnic backgrounds, and it will follow 450 caregiver-child pairs over a few years to see how their eating habits and weight change as kids grow from preschool to

  NIH research Temple Univ of the Commonwealth · Philadelphia, United States · NIH-11004331

• Improving healthy eating practices in early childhood education settings

  This study is all about helping young kids eat healthier in early care and education settings by using fun activities, role models, and a friendly mascot to encourage them to enjoy fruits and vegetables, while also making sure that the support given to teachers fits their needs.

  NIH research Univ of Arkansas for Med Scis · Little Rock, United States · NIH-10912472

• Preventing obesity in children with Down syndrome

  This study is looking at ways to help prevent obesity in children with Down syndrome by understanding what factors might contribute to weight gain, and it involves working closely with families to find the best strategies for keeping these kids healthy as they grow up.

  NIH research Colorado State University · Fort Collins, United States · NIH-10912001

• Preventing obesity in new mothers at risk for heart disease

  This study is all about helping new moms, especially those at risk for heart problems, to manage their weight after having a baby by using fun and supportive ways to encourage healthy habits.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-10908432

• Preventing obesity in young Hispanic children through family education

  This study is all about helping Hispanic families with young children by creating a fun, bilingual social media program that gives pregnant women and moms tips on healthy eating, breastfeeding, and good sleep habits to prevent obesity in their little ones.

  NIH research University of Miami Coral Gables · Coral Gables, United States · NIH-10899565

• Improving community efforts to prevent childhood obesity

  This study is looking at how groups in your community can work together better to use proven methods to help prevent childhood obesity, especially in neighborhoods that face economic challenges, so that kids can lead healthier lives.

  NIH research Tufts University Boston · Boston, United States · NIH-10886800

• A web-based training program to help Hispanic women prevent obesity

  This study is creating an online training program for community health workers to help Hispanic women learn how to prevent obesity through healthy eating and exercise, making it easier for them to support their communities in a way that fits their culture and lifestyle.

  NIH research Isa Associates, INC. · Arlington, UNITED STATES · NIH-10783802

• Preventing obesity in adolescents through a school-based program in Louisiana

  This study is testing a fun program called ProudMe to help kids aged 11-13 in Louisiana schools eat healthier and be more active, while also getting feedback from students, teachers, and parents to see how well it works.

  NIH research Louisiana State Univ A&m Col Baton Rouge · Baton Rouge, United States · NIH-10579702

• Investigating how certain fatty acids can help prevent obesity

  This study is looking at how certain healthy fats can help your body burn more energy and prevent weight gain, and it could lead to new ways for adults to manage their weight without the usual side effects of other methods.

  NIH research University of Tennessee Knoxville · Knoxville, United States · NIH-10438276

Related topics

Quick answers

How many Obesity Prevention clinical trials are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (10 trials), Spain (2 trials), Luxembourg (1 trial), Germany (1 trial), Cyprus (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →