NIH-funded research R01 grant

Obesity Prevention Targets for Down Syndrome

Funded at Colorado State University · NIH-11385544 · Data updated 2026-11-12

A study to find early, practical ways to prevent overweight and obesity in children and adults with Down syndrome.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColorado State University
NIH-funded
Lab location1 site (Fort Collins, United States)
Project startSeptember 3, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$622,938
NIH project number5R01HD105233-05
Project IDNIH-11385544 on NIH RePORTER

Who could benefit from this research

Could help

Children and adults with Down syndrome, including ages from early childhood through adulthood, who are at risk for overweight/obesity.

Less likely to help

Individuals without Down syndrome or those not experiencing overweight/obesity risk may see limited direct benefits.

What this research studies

This project follows children with Down syndrome from early childhood into later years to identify factors that increase or reduce obesity risk. Researchers will track growth, activity, sleep, feeding, and related health conditions over time to spot modifiable targets for prevention. The goal is to guide simple, effective steps that families and clinicians can use to keep people with DS healthier as they grow. The study builds on DS-specific knowledge to tailor prevention for this high-risk group.

Why it matters

Potential benefit: If successful, the project could inform personalized, DS-specific obesity prevention strategies that improve long-term health and quality of life.

How similar studies have gone: Previous DS obesity research has mainly described prevalence; this study aims to identify predictors to guide prevention, which is a novel but building field with promising precedents.

Where this research is happening

  • Colorado State University
    Fort Collins, United States
    Active

Researchers

  • Principal investigator: Daunhauer, Lisa Ann — Colorado State University
  • Study coordinator: Daunhauer, Lisa Ann

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.