Preventing excess weight in young children with Down syndrome

Obesity Prevention Targets for Down Syndrome

NIH-funded research Colorado State University · NIH-11176816

This project will test ways to prevent excess weight in young children with Down syndrome by tracking their growth, eating, activity, and sleep.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColorado State University NIH-funded
Lab location1 site (Fort Collins, United States)
Project IDNIH-11176816 on NIH RePORTER

What this research studies

We will follow young children with Down syndrome over several years and visit them regularly to measure weight, diet, physical activity, motor skills, and sleep. Caregivers will report on feeding habits, daily routines, and any medical concerns. The team will combine these measurements to identify which factors most strongly drive early weight gain. Findings will point to practical targets caregivers and clinicians can use to help children stay at healthier weights as they grow.

Who could benefit from this research

Good fit: Young children with Down syndrome—particularly around ages 2–6—and their caregivers who can attend regular study visits and complete caregiver questionnaires.

Not a fit: People without Down syndrome or adults with long-standing obesity who are outside the early-childhood prevention window are unlikely to benefit directly from this study.

Why it matters

Potential benefit: Could identify changeable habits and care practices that prevent overweight and obesity in children with Down syndrome, improving long-term health outcomes.

How similar studies have performed: Most prior work has been retrospective and descriptive, so this prospective, longitudinal approach for early obesity prevention in Down syndrome is relatively new.

Where this research is happening

Fort Collins, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.