Condition

Movement Disorders clinical trials and research

• 23Clinical trials
• 7NIH research projects
• 14Countries

Newest Movement Disorders clinical trials

All recruiting trials (23)

• Developing algorithms to restore complex movement after paralysis using non-invasive sensors in healthy volunteers

  This project tests whether signals from non-invasive sensors worn by healthy volunteers can train algorithms to control computers or assistive devices that might help people with paralysis.

  Recruiting University of California, Los Angeles · Los Angeles, California · NCT07236892

• Long-read genome sequencing to help diagnose dystonia

  Researchers test long-read genome sequencing to see if it can provide a genetic diagnosis for people with dystonia and related movement disorders when standard tests have not.

  Recruiting University Hospital, Strasbourg, France · Montpellier and 3 other locations · NCT06999096

• Registry and natural history of epilepsy-dyskinesia syndromes

  This registry will collect health data and biological samples from people of all ages who have a genetic diagnosis of epilepsy-dyskinesia syndromes to see how their genes relate to their movement and seizure symptoms over time.

  Recruiting Boston Children's Hospital · Boston, Massachusetts · NCT06967727

• Registry and biobank for neuroimmunological diseases

  This study is trying to see if certain antibodies in the brain are linked to neurological disorders like encephalopathy and psychosis, and how they might affect patients' health.

  Recruiting at 2 sites Charite University, Berlin, Germany · Berlin, State of Berlin and 1 other locations · NCT06958341

• Brain activity in movement disorders: basal ganglia, thalamus, and cerebellum

  We will record brain electrical signals from adults with movement disorders, both with and without deep brain stimulators, to see if specific signal patterns match their symptoms.

  Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT06848530

• Mindfulness program for people with Parkinson's and their caregivers

  This study tests whether a mindfulness program can help people with Parkinson's and their caregivers feel better emotionally and improve their relationship.

  Recruiting The University of Hong Kong · Hong Kong · NCT06821230

• Collecting data on neurodegenerative diseases progression markers

  This study is trying to find new signs that can help doctors understand how neurodegenerative diseases like Parkinson's progress, so they can improve early treatment options for patients.

  Recruiting IRCCS San Raffaele Roma · Cassino, Frosinone · NCT06596746

• Registry for pediatric deep brain stimulation outcomes

  This study is creating a database to collect information on how deep brain stimulation helps children with movement disorders like dystonia and Tourette syndrome, to see how safe and effective the treatment is.

  Recruiting Boston Children's Hospital · Boston, Massachusetts · NCT06585618

• Understanding epilepsy-dyskinesia syndromes in children

  This study is trying to learn more about epilepsy-dyskinesia syndromes in children by gathering information from different countries to see how these movement and seizure disorders are related.

  Recruiting Boston Children's Hospital · Boston, Massachusetts · NCT06585605

• Outcomes of radiofrequency ablation for movement disorders

  This study looks at how well a specific treatment called radiofrequency ablation works for people with movement disorders like Parkinson's disease and essential tremor.

  Recruiting at 4 sites Boston Scientific Corporation · Cologne and 3 other locations · NCT06553625

• Comparing different exercise volumes for veterans with moderate Parkinson's disease

  This study is testing whether veterans with moderate Parkinson's disease benefit more from high-volume dance exercise or moderate-volume walking to improve their physical activity and walking speed.

  Recruiting VA Office of Research and Development · Decatur, Georgia · NCT06088355

• Wearable lower-limb exoskeleton to stretch legs and improve walking

  This research will test a portable wearable exoskeleton to help people with spasticity from spinal cord injury increase leg range of motion and improve walking.

  Recruiting VA Office of Research and Development · Syracuse, New York · NCT05926596

• Identifying brain biomarkers for cognitive decline after Deep Brain Stimulation in Parkinson's Disease

  This study is trying to find brain markers that can help predict how people with Parkinson's Disease will think and remember after getting Deep Brain Stimulation.

  Recruiting Medical University of South Carolina · Charleston, South Carolina · NCT05822388

• Validating a new algorithm to measure daily energy expenditure in people with movement limitations

  This study is testing a new device that measures how much energy people with movement limitations use in a day to see if it's more accurate than the current methods.

  Recruiting University of Wisconsin, Milwaukee · Milwaukee, Wisconsin · NCT05736302

• Evaluating human movement with assistive devices

  This study tests how well different assistive devices help people with limb weakness or paralysis move around in everyday situations.

  Recruiting Orthocare Innovations, LLC · Edmonds, Washington · NCT05729061

• Registry for Exablate Neuro treatment in Parkinson's Disease

  This study is tracking 60 people with advanced Parkinson's Disease to see how well a new treatment using the Exablate Neuro device works for those who haven't had success with medications.

  Recruiting at 5 sites InSightec · Baltimore, Maryland and 4 other locations · NCT05539196

• Genetic analysis of hereditary spastic paraplegia

  This study is trying to find out the genetic causes of hereditary spastic paraplegia to help improve diagnosis and treatment for people living with this condition.

  Recruiting Boston Children's Hospital · Boston, Massachusetts · NCT05354622

• Using brain-computer interfaces to control assistive devices for motor recovery

  This study tests whether using brain-computer interfaces can help people with motor disorders control assistive devices better and improve their movement skills.

  Recruiting University of Texas at Austin · Austin, Texas · NCT05183152

• Creating a biorepository of biofluids and clinical data for ALS research

  This study is collecting blood, spinal fluid, and urine samples from people with ALS and healthy individuals to help find new ways to understand and treat the disease.

  Recruiting at 12 sites Target ALS Foundation, Inc. · Phoenix, Arizona and 11 other locations · NCT05137665

• Smartphone app to boost exercise in Parkinson's patients

  This study tests if a smartphone app can help people with Parkinson's Disease exercise more and improve their fitness over a year.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT04848077

• Long-term evaluation of Abbott deep brain stimulation systems for movement disorders

  This study is testing how safe and effective Abbott deep brain stimulation systems are for people with movement disorders like Parkinson's disease over a five-year period.

  Recruiting at 24 sites Abbott Medical Devices · Tucson, Arizona and 47 other locations · NCT04071847

• Investigating brain activity in movement disorders like Parkinson's disease

  This study is trying to see how brain activity changes during surgery for people with Parkinson's disease and essential tremor to find better ways to treat both movement and non-movement symptoms.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT04061135

• Using botulinum toxin to treat involuntary movement disorders

  This study tests whether botulinum toxin can help people with involuntary movement disorders by customizing the treatment for each patient and using special techniques to give the injections.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT00001208

NIH-funded research (7)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• AI-powered 3D tools to improve Parkinson’s care

  A new AI-based system uses 3D data to help doctors diagnose and manage Parkinson’s disease, with a focus on rural patients who often have limited access to specialists.

  NIH research Emory University · Atlanta, United States · NIH-11450678

• Cerebellum-targeted deep brain stimulation for severe movement problems and spasticity in cerebral palsy

  This project tests whether implanted electrodes that stimulate a cerebellar motor area can reduce severe involuntary movements and muscle tightness in children and young adults with cerebral palsy.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11322723

• Why brain cells cause movement and coordination problems

  Learning how a faulty ATXN1 gene in people with spinocerebellar ataxia type 1 damages cerebellar brain cells and leads to adult-onset balance and coordination problems.

  NIH research Northwestern University · Chicago, United States · NIH-11237574

• Using brain stimulation to improve movement in children with cerebral palsy

  This study is looking at how a special treatment called deep brain stimulation can help kids and young adults with cerebral palsy by improving their movement and reducing stiffness, and we're inviting ten participants to see if this approach makes a difference for them.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11055281

• Understanding genetic causes of movement disorders

  This study is looking for the genetic reasons behind movement disorders like Parkinson's disease and ataxias, and if you have unexplained movement issues, you might be able to help us find new genes that could explain your condition!

  NIH research VA Puget Sound Healthcare System · Seattle, United States · NIH-10977038

• Changing how people interpret threats to help reduce anxiety in movement disorders

  This study is testing a friendly online program designed to help people with movement disorders like Huntington's and Parkinson's manage their anxiety by teaching them to think about tricky situations in a more positive way.

  NIH research University of Virginia · Charlottesville, United States · NIH-10932105

• Investigating brain activity tracking in movement disorders using implanted sensors

  This study is looking at how a protein called ubiquilin-2 interacts with clumps of proteins in diseases like Alzheimer's and Parkinson's, and it involves placing small sensors under the scalp to monitor brain activity, which could help find new ways to treat these conditions and improve patients' lives.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10893983

Related topics

Quick answers

How many Movement Disorders clinical trials are recruiting right now?

23, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in United States (17 trials), Germany (3 trials), France (2 trials), Italy (2 trials), United Kingdom (2 trials). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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