Investigating brain activity tracking in movement disorders using implanted sensors
An investigation into chronic implanted subgaleal electroencephalography for neurophysiological biomarker tracking in movement disorders
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10893983
This study is looking at how a protein called ubiquilin-2 interacts with clumps of proteins in diseases like Alzheimer's and Parkinson's, and it involves placing small sensors under the scalp to monitor brain activity, which could help find new ways to treat these conditions and improve patients' lives.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10893983 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how a specific protein, ubiquilin-2, interacts with aggregated proteins in neurodegenerative diseases like Alzheimer's and Parkinson's. By using implanted subgaleal electroencephalography, the study aims to track neurophysiological biomarkers that could provide insights into movement disorders. Patients may have sensors placed under their scalp to monitor brain activity and protein interactions over time, helping researchers understand the underlying mechanisms of these diseases. The goal is to identify potential therapeutic targets that could improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias, as well as those with movement disorders like Parkinson's disease.
Not a fit: Patients with movement disorders not related to neurodegenerative diseases or those without a diagnosis of Alzheimer's or related dementias may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that better manage or even reverse symptoms of movement disorders associated with neurodegenerative diseases.
How similar studies have performed: Previous research has shown promising results in understanding protein interactions in neurodegenerative diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SANDOVAL-PISTORIUS, STEPHANIE SUZETTE — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: SANDOVAL-PISTORIUS, STEPHANIE SUZETTE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer's disease and related dementia, Alzheimer's disease and related disorders, Alzheimer's disease or a related dementia