Investigating brain activity tracking in movement disorders using implanted sensors
Official title: An investigation into chronic implanted subgaleal electroencephalography for neurophysiological biomarker tracking in movement disorders
Funded at University of California, San Francisco · NIH-10893983 · Data updated 2026-11-12
This study is looking at how a protein called ubiquilin-2 interacts with clumps of proteins in diseases like Alzheimer's and Parkinson's, and it involves placing small sensors under the scalp to monitor brain activity, which could help find new ways to treat these conditions and improve patients' lives.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | July 1, 2020 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $92,192 |
| NIH project number | 5K00NS118719-05 |
| Project ID | NIH-10893983 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias, as well as those with movement disorders like Parkinson's disease.
✕Less likely to help
Patients with movement disorders not related to neurodegenerative diseases or those without a diagnosis of Alzheimer's or related dementias may not benefit from this research.
What this research studies
This research focuses on understanding how a specific protein, ubiquilin-2, interacts with aggregated proteins in neurodegenerative diseases like Alzheimer's and Parkinson's. By using implanted subgaleal electroencephalography, the study aims to track neurophysiological biomarkers that could provide insights into movement disorders. Patients may have sensors placed under their scalp to monitor brain activity and protein interactions over time, helping researchers understand the underlying mechanisms of these diseases. The goal is to identify potential therapeutic targets that could improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that better manage or even reverse symptoms of movement disorders associated with neurodegenerative diseases.
How similar studies have gone: Previous research has shown promising results in understanding protein interactions in neurodegenerative diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Sandoval-Pistorius, Stephanie Suzette — University of California, San Francisco
- Study coordinator: Sandoval-Pistorius, Stephanie Suzette
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.