Outcomes of radiofrequency ablation for movement disorders
Official title: Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System
Run by Boston Scientific Corporation · NCT06553625 · Data updated 2026-11-12
This study looks at how well a specific treatment called radiofrequency ablation works for people with movement disorders like Parkinson's disease and essential tremor.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Boston Scientific Corporation Industry-sponsored |
| Locations | 4 sites (Cologne and 3 other locations) |
| Status | Recruiting |
| Started | January 29, 2024 |
| Main results expected | December 2035 |
| Study ends | December 2035 |
| Registry record updated | October 13, 2026 |
| Trial ID | NCT06553625 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients scheduled for treatment with a Boston Scientific RF system for CNS applications who can provide informed consent.
✕Probably not a fit
Patients with cognitive impairments or other characteristics that limit their ability to assess pain relief or complete study assessments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to gather real-world outcomes from patients undergoing treatment with Boston Scientific's commercially approved radiofrequency (RF) ablation systems for central nervous system applications. It focuses on conditions such as Parkinson's disease, dystonia, essential tremor, and other movement disorders. Participants will be treated with RF ablation as part of their functional neurosurgery, and their outcomes will be documented to assess the effectiveness of the intervention in a clinical setting.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the effectiveness of RF ablation for treating movement disorders, potentially improving patient care.
How similar studies have gone: Other studies using RF ablation for movement disorders have shown promising results, indicating that this approach has potential.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Study candidate is scheduled to be treated with a commercially approved Boston Scientific RF system for pain or for CNS applications per local Directions for Use (DFU) * Signed a valid, IRB/EC/REB-approved informed consent form Exclusion Criteria: * Meets any contraindications per locally applicable Directions for Use (DFU) * Currently diagnosed with cognitive impairment, or exhibits any characteristic, that would limit study candidate's ability to assess pain relief or to complete study assessments
Where it's running
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Uniklinik Köln
Cologne, Germany Recruiting -
Universitaetsklinikum Dusseldorf
Düsseldorf, Germany Recruiting -
Universitaetsklinikum Wuerzburg
Würzburg, Germany Recruiting -
St. Georges Hospital
London, United Kingdom Recruiting
Study contacts
- Study coordinator: Stephanie Delvaux
- Email: BSNClinicalTrials@bsci.com
- Phone: 855-213-9890
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Long-term evaluation of Abbott deep brain stimulation systems for movement disorders
This study is testing how safe and effective Abbott deep brain stimulation systems are for people with movement disorders like Parkinson's disease over a five-year period.
-
Validation of a deep learning platform for diagnosing isolated dystonia
This study is testing a new deep learning tool to see if it can help doctors diagnose isolated dystonia more accurately and quickly.
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This study is trying to see how brain activity affects speaking in people with neurological disorders like Parkinson's disease and dystonia who are about to have deep brain stimulation surgery.
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Collecting clinical outcomes for deep brain stimulation in movement disorders
This study is tracking the experiences of people with movement disorders like Parkinson's disease who are getting deep brain stimulation to see how well it works and what risks it might have over time.
-
Evaluating outcomes of Deep Brain Stimulation for movement disorders
This study looks at how well Deep Brain Stimulation works for people with Parkinson's Disease, Essential Tremor, and Dystonia by reviewing past patient records.
-
Investigating the relationship between genetic mutations and brain changes in dystonia
This study is trying to see how genetic changes linked to dystonia affect the brain in people with the condition compared to healthy individuals.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.