Genetic analysis of hereditary spastic paraplegia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The HSP Sequencing Initiative aims to enhance understanding of the genetic factors involved in hereditary spastic paraplegia (HSP) and related neurodegenerative disorders. This observational study will collect detailed phenotype information and perform high-resolution DNA analyses to identify genetic causes of HSP. By studying a large sample of the HSP population, the initiative seeks to establish connections between clinical features and genetic mechanisms, ultimately leading to improved diagnostic and treatment strategies for affected individuals.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical diagnosis of progressive spasticity

Where it's running

• Boston Children's Hospital
  Boston, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: Darius Ebrahimi-Fakhari, MD, PhD — Boston Children's Hospital
• Study coordinator: Darius Ebrahimi-Fakhari, MD, PhD
• Email: hsp.research@childrens.harvard.edu
• Phone: 617-355-8356

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.