Condition

Lupus Erythematosus, Systemic clinical trials and research

• 20Clinical trials
• 35Countries

Newest Lupus Erythematosus, Systemic clinical trials

All recruiting trials (20)

• Pain patterns in rheumatic diseases: see if pain works differently in patients and healthy people

  This observational study tests how pain is experienced and measured in people with rheumatic diseases compared with healthy volunteers.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07829497

• Anifrolumab in Chinese patients with active moderate-to-severe SLE

  This study tests whether adding anifrolumab to standard care helps Chinese adults with active moderate-to-severe SLE achieve remission and reduces glucocorticoid use.

  Recruiting at 25 sites Phase 3 AstraZeneca · Beijing and 73 other locations · NCT07751848

• Cevostamab in systemic lupus erythematosus with or without active lupus nephritis

  This study tests cevostamab in people with systemic lupus erythematosus, with or without active lupus nephritis, to see how safe it is and how the body handles it when added to standard care.

  Recruiting at 11 sites Phase 1 Genentech, Inc. · Parkville, Victoria and 10 other locations · NCT07629583

• Nipocalimab for adults with moderate to severe systemic lupus erythematosus

  This trial tests nipocalimab versus placebo in adults with moderate to severe lupus to see if it reduces disease activity and symptoms.

  Recruiting at 270 sites Phase 3 Janssen Research & Development, LLC · Beverly Hills, California and 271 other locations · NCT07438496

• Disease activity and quality of life in adults with SLE starting subcutaneous anifrolumab

  This project will try to see how subcutaneous anifrolumab works for adults with lupus by collecting clinical measurements and patient-reported outcomes in routine care.

  Recruiting at 21 sites AstraZeneca · Altenburg and 20 other locations · NCT07424261

• Anifrolumab to achieve LLDAS5 in people with systemic lupus erythematosus

  This study tests whether anifrolumab helps people with systemic lupus erythematosus reach and keep low disease activity while staying on 5 mg/day or less of corticosteroids.

  Recruiting at 14 sites AstraZeneca · Monserrato, CA and 21 other locations · NCT07330245

• Interferon patterns in cancer patients receiving CTLA-4 or PD-1/PD-L1 inhibitors versus autoimmune disease

  This project will test whether blood interferon levels can help predict immune-related side effects in adults starting checkpoint inhibitor immunotherapy by comparing them with people who have autoimmune diseases.

  Recruiting Hospital Universitario Araba · Pamplona, Navarre · NCT07249060

• Cenerimod added to standard treatment for active lupus nephritis

  This study will test whether taking cenerimod along with regular treatment helps adults with systemic lupus and active lupus nephritis improve their kidney function and is safe to use.

  Recruiting at 14 sites Phase 3 Viatris Inc. · Doral, Florida and 13 other locations · NCT07201129

• Evaluating CTX112 for treating refractory autoimmune diseases in adults

  This study is testing a new CAR T cell treatment called CTX112 to see if it can help adults with tough autoimmune diseases like lupus and scleroderma feel better.

  Recruiting at 16 sites Phase 1 CRISPR Therapeutics · La Jolla, California and 16 other locations · NCT06925542

• Investigating AZD0120 for treating adults with refractory lupus

  This study is testing a new treatment called AZD0120 to see if it can help adults with hard-to-treat lupus feel better.

  Recruiting at 11 sites Phase 1/2 AstraZeneca · San Francisco, California and 19 other locations · NCT06897930

• Tracking organ damage in lupus patients

  This study is trying to see if tracking changes in lupus patients can help predict serious organ damage, especially in the kidneys and lungs, while they are treated with certain medications.

  Recruiting Chinese SLE Treatment And Research Group · Beijing, Beijing Municipality · NCT06887517

• Vunakizumab for mild to moderate lupus

  This trial will test whether the antibody vunakizumab helps adults with mild to moderate lupus reduce skin and joint symptoms.

  Recruiting Phase 1 Chinese SLE Treatment And Research Group · Beijing, Beijing Municipality · NCT06881290

• Examining the effects of different exercise levels on arthritis symptoms

  This study tests how different amounts of exercise can help people with arthritis feel better over six months.

  Recruiting University of South Carolina · Columbia, South Carolina · NCT06880653

• Effects of phytocannabinoids on immune response in chronic inflammatory diseases

  This study is testing whether phytocannabinoids like CBD and THC can help improve the immune response in people with chronic inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.

  Recruiting Centre Hospitalier Régional d'Orléans · Orléans · NCT06842316

• Using CAR T-cell therapy to treat severe autoimmune diseases

  This study is testing if a new CAR T-cell therapy can help people with severe autoimmune diseases like lupus and scleroderma feel better.

  Recruiting Phase 1/2 Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome, Lazio · NCT06685042

• Using CNCT19 cell therapy to treat difficult autoimmune diseases

  This study tests if a new cell therapy called CNCT19 can help people with tough autoimmune diseases like lupus feel better when other treatments haven't worked.

  Recruiting Early Phase 1 Juventas Cell Therapy Ltd. · Zhengzhou, Henan · NCT06316791

• Online therapy for managing pain in fibromyalgia and lupus patients

  This study is testing an online therapy called Brief Pain Exposure Therapy to see if it can help adults with fibromyalgia and lupus manage their pain and improve their overall well-being.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06208514

• High-intensity interval training for patients with lupus

  This study is testing whether a special exercise program that includes high-intensity workouts can help people with lupus improve their fitness, muscle strength, and overall well-being.

  Recruiting Karolinska Institutet · Stockholm, Huddinge · NCT06166199

• Evaluating belimumab for early lupus treatment

  This study is testing if the drug belimumab can help people who have been diagnosed with lupus in the last two years feel better and possibly stay in remission.

  Recruiting Phase 4 Northwell Health · Manhasset, New York · NCT03543839

• Collection of samples from patients with rheumatic diseases

  This study is collecting samples from people with rheumatic diseases to help researchers learn more about these conditions and improve treatments in the future.

  Recruiting Meir Medical Center · Kfar Saba · NCT03473912

Related topics

Quick answers

How many Lupus Erythematosus, Systemic clinical trials are recruiting right now?

20, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 35 countries. The most sites are in United States (8 trials), China (6 trials), Spain (4 trials), Italy (4 trials), Germany (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Phase 3: 3, Phase 1/2: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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