Examining the effects of different exercise levels on arthritis symptoms
Examination of the Dose Response Relationship Between Physical Activity and Arthritis-Attributable Outcomes
This study tests how different amounts of exercise can help people with arthritis feel better over six months.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 285 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of South Carolina Academic / other |
| Locations | 1 site (Columbia, South Carolina) |
| Trial ID | NCT06880653 on ClinicalTrials.gov |
What this trial studies
This study investigates how varying levels of physical activity (45, 90, or 150 minutes per week) impact symptoms of arthritis, including rheumatoid arthritis, gout, fibromyalgia, and osteoarthritis. Participants will be randomly assigned to one of the three activity goals and will receive a comprehensive 6-month program that includes the Arthritis Foundation's Walk With Ease Guidebook, behavioral lessons, a Fitbit for tracking, and monthly coaching calls. Additional support through calls, texts, or emails will be provided to help participants meet their goals.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with a doctor-diagnosed form of arthritis or related conditions.
Not a fit: Patients who are contraindicated to exercise or already engage in significant physical activity may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management of arthritis symptoms through tailored exercise regimens.
How similar studies have performed: Previous studies have shown positive outcomes with exercise interventions for arthritis management, suggesting this approach is promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years or older * Have a doctor diagnosed form of arthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia * Ability to read and write in English Exclusion Criteria: * Have any contraindications to exercise (besides arthritis) * Engage in \>45 min/week of Actigraph assessed moderate to vigorous intensity activity * Are pregnant, breastfeeding, or planning to become pregnant in the next year * Are planning to relocate out of the Columbia, SC area in the next 12 months, * Do not have a device compatible with Fitbit * Have uncontrolled hypertension (e.g., systolic blood pressure \> 160 mmHg or diastolic blood pressure \> 100 mmHg) * Plan to have a surgery that affects mobility in the next 12 months * Have a serious cognitive impairment. * Not willing to be randomized to any of the 3 conditions, do not believe they could adhere to the goals, or do not believe they could achieve the highest dose of activity (150 minutes/week).
Where this trial is running
Columbia, South Carolina
- University of South Carolina — Columbia, South Carolina, United States (Recruiting)
Study contacts
- Principal investigator: Christine Pellegrini, PhD — University of South Carolina
- Study coordinator: Ellen Wingard
- Email: EWINGARD@mailbox.sc.edu
- Phone: 803-777-1889
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.