NIH-funded research NIH-funded research

Using a device at home to stimulate a nerve in the ear to help manage pain in young adults with IBS

Official title: Home-Based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Pain and Symptom Management among Young Adults with Irritable Bowel Syndrome (IBS)

Funded at Yale University · NIH-11122461 · Data updated 2026-11-12

This study is looking at whether a gentle ear stimulation technique done at home can help young adults with irritable bowel syndrome (IBS) feel better by easing their pain and symptoms.

More Irritable Bowel Syndrome research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startApril 1, 2025
Project endMarch 31, 2028
Funding year2025
Award (this year)$762,489
NIH project number1R34AT012917-01A1
Project IDNIH-11122461 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are young adults aged 18-29 who have been diagnosed with irritable bowel syndrome.

Less likely to help

Patients outside the age range of 18-29 or those not diagnosed with irritable bowel syndrome may not benefit from this research.

What this research studies

This research investigates the use of home-based transcutaneous auricular vagus nerve stimulation (taVNS) as a non-invasive method to help manage pain and symptoms in young adults suffering from irritable bowel syndrome (IBS). The approach focuses on stimulating a specific nerve in the ear to potentially improve the brain-gut interaction and alleviate distressing symptoms associated with IBS. Participants will be involved in a randomized trial comparing the effects of active taVNS versus a sham treatment, assessing factors such as feasibility, safety, and adherence to the intervention. This study aims to explore a practical and accessible pain management strategy for young adults aged 18-29 with IBS.

Why it matters

Potential benefit: If successful, this research could provide a new, effective, and non-pharmacological treatment option for managing IBS-related pain and symptoms in young adults.

How similar studies have gone: Previous research has shown promise for non-pharmacological interventions like taVNS in various populations, suggesting potential success for this approach in young adults with IBS.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Cong, Xiaomei Sophia — Yale University
  • Study coordinator: Cong, Xiaomei Sophia

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.