Using a device at home to stimulate a nerve in the ear to help manage pain in young adults with IBS

Home-Based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Pain and Symptom Management among Young Adults with Irritable Bowel Syndrome (IBS)

NIH-funded research Yale University · NIH-11122461

This study is looking at whether a gentle ear stimulation technique done at home can help young adults with irritable bowel syndrome (IBS) feel better by easing their pain and symptoms.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11122461 on NIH RePORTER

What this research studies

This research investigates the use of home-based transcutaneous auricular vagus nerve stimulation (taVNS) as a non-invasive method to help manage pain and symptoms in young adults suffering from irritable bowel syndrome (IBS). The approach focuses on stimulating a specific nerve in the ear to potentially improve the brain-gut interaction and alleviate distressing symptoms associated with IBS. Participants will be involved in a randomized trial comparing the effects of active taVNS versus a sham treatment, assessing factors such as feasibility, safety, and adherence to the intervention. This study aims to explore a practical and accessible pain management strategy for young adults aged 18-29 with IBS.

Who could benefit from this research

Good fit: Ideal candidates for this research are young adults aged 18-29 who have been diagnosed with irritable bowel syndrome.

Not a fit: Patients outside the age range of 18-29 or those not diagnosed with irritable bowel syndrome may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective, and non-pharmacological treatment option for managing IBS-related pain and symptoms in young adults.

How similar studies have performed: Previous research has shown promise for non-pharmacological interventions like taVNS in various populations, suggesting potential success for this approach in young adults with IBS.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.