Condition

Gastrointestinal Microbiome clinical trials and research

• 11Clinical trials
• 4NIH research projects
• 6Countries

Newest Gastrointestinal Microbiome clinical trials

All recruiting trials (11)

• Gut microbes and blood signals in sepsis-related liver and kidney injury

  This study tests whether gut microbes and blood markers differ in adults with sepsis who develop liver or kidney injury, compared with healthy volunteers.

  Recruiting at 6 sites First Affiliated Hospital of Zhejiang University · Hangzhou, Zhejiang and 5 other locations · NCT07735182

• Plant-based beverage effects on the gut microbiome in healthy adults

  This study tests how drinking different plant-based beverages for two weeks affects the gut microbiome in healthy adults.

  Recruiting Lund University · Lund, Skåne County · NCT07730229

• Inulin Prebiotic for Perimenopausal Women with Overweight or Obesity

  This study tests whether 2 weeks of inulin can affect gut and vaginal microbes, heart health, and muscle health in perimenopausal women who are overweight or obese, using a crossover design.

  Recruiting George Washington University · Washington D.C., District of Columbia · NCT07724522

• Preoperative Fasting to Shape the Gut with Hip Replacement

  This trial tests whether a 20-day preoperative fasting plan can lower inflammatory signals and broaden gut microbes in adults undergoing total hip arthroplasty.

  Recruiting Charite University, Berlin, Germany · Berlin, State of Berlin · NCT07651462

• A nutritional supplement to fill nutrient gaps and support gut health for people taking GLP-1 medications.

  This study will test whether a daily nutritional supplement can reduce nutrient gaps and improve the gut microbiome in adults who are using GLP-1 receptor agonist medications.

  Recruiting Athletic Greens International · Santa Monica, California · NCT07437911

• Exploring sleep disorders in ulcerative colitis patients

  This study looks at how sleep problems affect people with ulcerative colitis and what that means for their overall health and gut bacteria.

  Recruiting Xijing Hospital · Xi'an, Shaanxi · NCT06359808

• Examining the effects of a Mediterranean diet on Parkinson's Disease

  This study is trying out a Mediterranean diet for people with Parkinson's Disease to see if it helps improve their symptoms and overall health compared to a regular diet.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT06207136

• Using fecal microbiota transplantation to reduce colorectal adenoma recurrence

  This study tests if a treatment using healthy gut bacteria can help prevent the return of colorectal adenomas in patients who have had them removed.

  Recruiting Phase 2 Shenzhen Hospital of Southern Medical University · Guangzhou, Guangdong and 4 other locations · NCT06205862

• Effects of coffee on gut microbiome and liver health in colorectal cancer patients

  This study is testing whether drinking 6 grams of freeze-dried instant coffee daily can improve liver health and gut bacteria in people who have finished treatment for colorectal cancer.

  Recruiting Phase 1/2 Massachusetts General Hospital · Boston, Massachusetts · NCT05692024

• Exploring exercise and molecular factors in cancer-related muscle loss

  This study tests whether exercise can help people with non-small cell lung cancer who are losing muscle mass feel better and improve their quality of life.

  Recruiting University of Copenhagen · Copenhagen, DK · NCT05307367

• Vaginal microbiome exposure for newborns delivered by C-section

  This study is testing if exposing newborns delivered by C-section to their mother’s vaginal bacteria can improve their health and development over the first three years of life.

  Recruiting Phase 1/2 National Institute of Allergy and Infectious Diseases (NIAID) · Falls Church, Virginia · NCT03298334

NIH-funded research (4)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Mapping and controlling interactions in the human gut microbiome

  This project builds lab tools to map how gut bacteria interact with each other and with human cells, aiming to enable targeted changes that could help people with gut-related conditions.

  NIH research Georgia Institute of Technology · Atlanta, United States · NIH-11312687

• HIV reservoirs in the gut and how they reactivate when treatment stops

  This grant explores how HIV hides in the gut and why it can come back when ART is paused, with the goal of guiding better cure strategies.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11124594

• Mapping interactions in the human gut microbiome

  This study is all about figuring out how different bacteria in your gut work together and with your body, so we can find new ways to help improve gut health for everyone.

  NIH research Georgia Institute of Technology · Atlanta, United States · NIH-11061015

• Understanding how genetic elements affect gut bacteria diversity

  This study is looking at how certain genetic elements in bacteria help them adapt and survive in our gut, specifically focusing on a type of bacteria called Bacteroides, to better understand how these changes affect the balance and health of our gut microbiome.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11005727

Related topics

Quick answers

How many Gastrointestinal Microbiome clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (4 trials), China (3 trials), Canada (1 trial), Sweden (1 trial), Denmark (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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