Condition

Fecal Microbiota Transplantation clinical trials and research

• 10Clinical trials
• 12NIH research projects
• 7Countries

Newest Fecal Microbiota Transplantation clinical trials

All recruiting trials (10)

• Fecal transplant plus standard therapy for refractory hepatic encephalopathy after TIPS

  This study tests whether adding fecal microbiota transplantation to usual medicines helps people with recurrent hepatic encephalopathy after TIPS implant.

  Recruiting Early Phase 1 Air Force Military Medical University, China · Xi'an · NCT07683936

• Using fecal microbiota transplantation to prevent infections after liver transplantation

  This study is testing if a special treatment using healthy stool can help prevent infections in people getting a liver transplant.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna · NCT06782880

• Maternal fecal transplant for babies born by cesarean section

  This trial will try giving a small fecal transplant from the mother to newborns delivered by elective C-section to see if it improves their gut microbiome and lowers the risk of later overweight or obesity.

  Recruiting Oulu University Hospital · Oulu · NCT06282952

• Using fecal microbiota transplantation to reduce colorectal adenoma recurrence

  This study tests if a treatment using healthy gut bacteria can help prevent the return of colorectal adenomas in patients who have had them removed.

  Recruiting Phase 2 Shenzhen Hospital of Southern Medical University · Guangzhou, Guangdong and 4 other locations · NCT06205862

• Using fecal transplantation to eliminate drug-resistant bacteria

  This study is testing whether using fecal transplants can help adults get rid of harmful drug-resistant bacteria in their gut.

  Recruiting Phase 3 Assistance Publique - Hôpitaux de Paris · Clichy and 10 other locations · NCT05035342

• Restoring gut bacteria in patients with Crohn's disease

  This study is testing whether a treatment using healthy gut bacteria can help people with active Crohn's disease feel better.

  Recruiting Phase 1/2 St Vincent's Hospital Melbourne · Melbourne, Victoria · NCT04970446

• Using fecal microbiota transplantation to treat various diseases

  This study is testing whether fecal microbiota transplantation can help people with various health issues related to gut imbalances, like digestive problems and autoimmune diseases.

  Recruiting Guangzhou First People's Hospital · Guangzhou, Guangdong · NCT04706611

• Fecal microbiota transplantation for treating ulcerative colitis

  This study is testing whether fecal microbiota transplantation can help people with moderate to severe ulcerative colitis feel better by restoring a healthy gut.

  Recruiting Phase 2/3 Guangzhou First People's Hospital · Guangzhou, Guangdong · NCT03804931

• Using fecal microbiota transplantation to treat irritable bowel syndrome

  This study is testing whether using healthy gut bacteria from donors can help people with irritable bowel syndrome feel better.

  Recruiting Phase 2/3 Guangzhou First People's Hospital · Guangzhou, Guangdong · NCT03613545

• National registry for fecal microbiota transplantation

  This study is collecting information from 4,000 patients who are getting fecal microbiota transplants to see how well the treatment works and what effects it has over time.

  Recruiting at 26 sites American Gastroenterological Association · Phoenix, Arizona and 52 other locations · NCT03325855

NIH-funded research (12)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Fecal transplant plus fiber to treat graft-versus-host disease after blood stem cell transplant

  A study to see if giving fecal transplant along with dietary fiber helps gut health and reduces complications in patients who have received a stem cell transplant and developed graft-versus-host disease.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11377663

• Proteolytic Activity-Guided Fecal Microbiota Transplant for PI-IBS

  A pilot study will test a targeted fecal microbiota transplant to help adults with post-infection irritable bowel syndrome feel better and have fewer GI symptoms.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11377587

• Fecal microbiota transplantation plus immune checkpoint blockers for solid tumors

  This project looks at whether changing gut bacteria with fecal transplants can boost how well cancer treatments called immune checkpoint blockers work in people with solid tumors.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11364138

• Fecal transplant treatment for auto-brewery (gut fermentation) syndrome

  This project gives capsule fecal microbiota transplants to adults with auto-brewery syndrome to try to stop their gut from producing alcohol and causing unexplained intoxication.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11197592

• A new way to use gut bacteria transplants for Irritable Bowel Syndrome

  This research explores if a special type of fecal microbiota transplant, guided by specific gut enzyme activity, can safely and effectively improve symptoms for adults with Irritable Bowel Syndrome that developed after an infection.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11176806

• Using gut bacteria to improve cancer treatment for solid tumors

  This research explores if changing gut bacteria through fecal microbiota transplantation can help immune checkpoint medicines work better for people with solid tumors.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11139449

• Using Fecal Microbiota Transplantation and Fiber to Treat Graft-versus-host Disease After Stem Cell Transplants

  This work explores how giving patients healthy gut bacteria and fiber might help manage graft-versus-host disease, a common issue after stem cell transplants.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11137074

• Using fecal microbiota transplantation to treat auto-brewery syndrome

  This study is looking at whether giving patients with auto-brewery syndrome a special treatment using healthy gut bacteria can help reduce their symptoms and improve their overall gut health.

  NIH research University of California, San Diego · La Jolla, United States · NIH-10985656

• Using fecal microbiota transplantation and fiber to treat graft-versus-host disease after blood cell transplants

  This study is looking at how using a special treatment called fecal microbiota transplantation, along with dietary fiber, can help improve gut health and recovery for patients dealing with graft-versus-host disease after a stem cell transplant.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-10908690

• Comparing two treatments for recurrent Clostridioides difficile infection

  This study is looking at how well a special live treatment works compared to a stool transplant for people who keep getting C. difficile infections, to see if it can help them feel better and improve their gut health in a safer way.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-10845658

• Using targeted fecal microbiota transplantation to treat irritable bowel syndrome

  This study is looking at whether a special treatment called fecal microbiota transplantation (FMT) can help people with irritable bowel syndrome (IBS) who started having symptoms after an intestinal infection, by using healthy gut bacteria from carefully chosen donors to improve their gut health.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-10773350

• Understanding how gut bacteria affect fecal microbiota transplantation for C. difficile infections

  This study is looking at how the bacteria in our guts can affect the success of a treatment called fecal microbiota transplantation (FMT) for people with recurring C. difficile infections, and it aims to help improve this treatment for better health outcomes.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-10668456

Related topics

Quick answers

How many Fecal Microbiota Transplantation clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in China (5 trials), Australia (1 trial), Finland (1 trial), Canada (1 trial), United States (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 2, Phase 2: 1, Phase 1/2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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