Condition

End Stage Kidney Disease clinical trials and research

• 13Clinical trials
• 15NIH research projects
• 37Countries

Newest End Stage Kidney Disease clinical trials

All recruiting trials (13)

• Staged kidney implantation with hypothermic oxygenated machine perfusion during combined heart and kidney transplants

  This trial will test whether keeping the donor kidney on oxygenated machine perfusion and implanting it later helps adults who are receiving both a heart and a kidney transplant.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06877169

• Moda-flx Hemodialysis System for clinic and at-home use

  This trial will test whether the Moda-flx Hemodialysis System can be used safely and effectively by trained professionals in clinics and by trained patients and care partners at home for adults with end-stage kidney disease.

  Recruiting at 5 sites Diality Inc. · San Dimas, California and 4 other locations · NCT06613568

• Inserting peritoneal dialysis catheters using a bedside technique

  This study is testing a new way to insert peritoneal dialysis catheters at the bedside for patients who can't have general anesthesia, to see if it can help more people access this treatment.

  Recruiting at 2 sites Universitair Ziekenhuis Brussel · Brussels and 1 other locations · NCT06065982

• Comparing two beta blockers for heart health in dialysis patients

  This study is testing which beta blocker, metoprolol or carvedilol, is better for heart health in veterans on dialysis to see if it can help them live longer and feel better.

  Recruiting at 12 sites Phase 3 VA Office of Research and Development · Long Beach, California and 17 other locations · NCT05931276

• Comparing Incremental Hemodialysis to Conventional Hemodialysis

  This study is testing if a new way of doing hemodialysis called incremental hemodialysis can help people with end-stage kidney disease feel better and have fewer hospital visits compared to the standard method.

  Recruiting at 10 sites Wake Forest University Health Sciences · Jacksonville, Florida and 9 other locations · NCT05828823

• Monitoring symptoms in patients undergoing hemodialysis

  This study is testing a new system that helps patients on hemodialysis report their symptoms more easily to see if it improves their care compared to regular check-ups.

  Recruiting University of Pennsylvania · Waltham, Massachusetts · NCT05738330

• Investigating the safety and mechanisms of SGLT2 inhibitors in patients on peritoneal dialysis

  This study is testing if a diabetes medication called empagliflozin is safe and helpful for people on peritoneal dialysis who still have some kidney function, to see if it can protect their heart and kidneys.

  Recruiting Phase 3 University Health Network, Toronto · Toronto, Ontario · NCT05715814

• Comparing isolated ultrafiltration to conventional hemodialysis in kidney disease patients

  This study is testing if a new method called isolated ultrafiltration can help people with end-stage kidney disease have a better experience during dialysis compared to the usual method.

  Recruiting Medical University of Graz · Graz · NCT05642156

• Inducing immunological tolerance in kidney transplant patients using stem cell infusion

  This study is testing whether giving stem cells from the same donor to kidney transplant patients can help them stop taking their immunosuppressive medications safely.

  Recruiting Phase 1 University of California, Los Angeles · Los Angeles, California · NCT05525507

• Testing CSL300 for heart health in dialysis patients with kidney disease

  This study is testing if a new treatment called CSL300 can improve heart health in dialysis patients with kidney disease and related conditions like diabetes or heart disease.

  Recruiting at 513 sites Phase 2/3 CSL Behring · Decatur, Alabama and 565 other locations · NCT05485961

• Biorepository for studying kidney disease in individuals with ApoL1 mutations

  This study is trying to understand how certain genetic changes in the ApoL1 gene affect kidney disease in people of African ancestry by collecting samples from those with and without kidney problems.

  Recruiting Duke University · Durham, North Carolina · NCT04160507

• Validating a new cardiac MRI technique for dialysis patients

  This study is testing a new type of heart scan to see if it can accurately show heart damage in people who are on dialysis.

  Recruiting University of Leicester · Leicester, Leicestershire · NCT03586518

• Evaluating the impact of sodium levels in dialysis on heart events

  This study is testing whether using different levels of sodium in dialysis can help reduce heart problems and deaths in people who are on hemodialysis.

  Recruiting at 263 sites Phase 4 University of Sydney · Adelaide and 263 other locations · NCT02823821

NIH-funded research (15)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• How dialysis facility growth affects care for people with end-stage kidney disease

  New research will examine whether the spread of dialysis centers and new treatment technologies benefit patients with end-stage kidney disease, and whether benefits reach all communities.

  NIH research National Bureau of Economic Research · Cambridge, United States · NIH-11434364

• Hospital-to-SNF Transitions for Kidney Failure Patients

  Aimed at improving how patients with end-stage kidney disease move from hospital to skilled nursing facilities to reduce readmissions.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11416733

• Medically tailored meals for children with kidney failure

  A study compares different ways to give tailored meals to kids with end-stage kidney disease to see what works best for families and health.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11415911

• Telehealth for rural patients with end-stage kidney disease

  A doctor-researcher at a major university is studying how telehealth can help people with advanced kidney disease in rural areas access care and stay on track for transplantation.

  NIH research University of Texas at Austin · Austin, United States · NIH-11415422

• Gout and Kidney Disease: How gout changes as kidney disease gets worse and after kidney transplant

  This project follows people with gout as their kidney disease progresses toward dialysis or transplant, using national kidney data to understand how often gout flares happen and how care needs change.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11370662

• Fistula versus graft for hemodialysis access in older adults

  This study compares two types of surgical dialysis access—fistulas and grafts—to find which is better for adults aged 65 and older who are using a catheter for hemodialysis.

  NIH research Wake Forest University Health Sciences · Winston-Salem, United States · NIH-11178427

• How climate change and wildfires affect patients with severe kidney disease

  This study looks at how extreme heat and wildfires affect people with end-stage kidney disease across the U.S., aiming to find out who is most at risk and how we can better protect them.

  NIH research Univ of Maryland, College Park · College Park, United States · NIH-11050045

• Understanding diabetes management in patients with end-stage kidney disease

  This study looks at how people with diabetes and severe kidney disease are treated, focusing on the risks of low and high blood sugar, to see how different diabetes medications affect their health and hospital visits, especially for those in minority groups who are more affected by these issues.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11042745

• Using at-home neurostimulation to reduce pain in patients with end-stage kidney disease on dialysis

  This study is looking at a new way to help people with end-stage kidney disease manage their pain at home during hemodialysis using a gentle electrical stimulation method, which could reduce the need for strong pain medications.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-10991001

• Comparing two types of vascular access for older adults on hemodialysis

  This study is looking at how well two types of surgeries for getting blood access work for older adults with severe kidney disease who need dialysis, to see which one helps them feel better and be happier with their treatment.

  NIH research Wake Forest University Health Sciences · Winston-Salem, United States · NIH-10912828

• How changes in red blood cell function affect heart health in kidney disease patients

  This study is looking at how changes in certain substances in your red blood cells might affect heart health for people with severe kidney disease who are on dialysis, with the goal of finding better ways to help keep your heart healthy.

  NIH research VA Greater Los Angeles Healthcare System · Los Angeles, United States · NIH-10909836

• Exploring how telehealth can help patients with end stage kidney disease in rural areas

  This study is looking at how using telehealth can help people with end stage kidney disease who live in rural areas get better access to care, and it will also find out what patients and doctors think about using telehealth instead of going to the office.

  NIH research University of Texas at Austin · Austin, United States · NIH-10909037

• Understanding weight loss in obese patients with end-stage kidney disease

  This study is looking at how losing weight can impact people with end-stage kidney disease who are also obese, to help find safer ways to manage their weight and improve their health while they’re on dialysis.

  NIH research Drexel University · Philadelphia, United States · NIH-10861854

• Exploring decision-making tools for older patients with end-stage kidney disease

  This study is testing a new tool called 'Best Case/Worst Case' to help older patients with advanced kidney disease make better choices about their treatment and care, so they can feel more in control and improve their quality of life.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-10796855

• How high temperatures affect kidney disease in US veterans

  This study is looking at how hot weather affects kidney health in US veterans who don’t have kidney disease yet, to see if high temperatures can lead to problems like chronic kidney disease or end-stage kidney disease.

  NIH research University of Memphis · Memphis, United States · NIH-10653610

Related topics

Quick answers

How many End Stage Kidney Disease clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 37 countries. The most sites are in United States (7 trials), United Kingdom (3 trials), Canada (3 trials), Australia (2 trials), Austria (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 2/3: 1, Phase 1: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →