Condition

Cutaneous T Cell Lymphoma clinical trials and research

• 17Clinical trials
• 12NIH research projects
• 5Countries

Newest Cutaneous T Cell Lymphoma clinical trials

All recruiting trials (17)

• Ruxolitinib maintenance after stem cell transplant for T‑cell lymphoma

  This phase II trial tests whether taking ruxolitinib after a stem cell transplant can lower the chance of relapse and graft‑versus‑host disease for people treated for T‑cell lymphoma.

  Recruiting at 2 sites Phase 2 Ohio State University Comprehensive Cancer Center · Columbus, Ohio and 1 other locations · NCT07356245

• Ropeginterferon treatment for cutaneous T‑cell lymphoma

  This trial tests whether ropeginterferon-alfa-2b helps people with cutaneous T‑cell lymphoma who have not responded adequately to multiple prior skin-directed therapies.

  Recruiting Phase 1 H. Lee Moffitt Cancer Center and Research Institute · Tampa, Florida · NCT07047885

• Personalized exercise and nutrition program to reduce cancer-related fatigue

  This program will try a personalized exercise and diet plan to reduce fatigue for adults with indolent lymphomas (including CLL/SLL and follicular lymphoma).

  Recruiting UNC Lineberger Comprehensive Cancer Center · Chapel Hill, North Carolina · NCT06860880

• Golidocitnib treatment for relapsed indolent T/NK-cell lymphomas

  This study is testing if a new oral medication called Golidocitnib can help people with relapsed indolent T/NK-cell lymphomas feel better after other treatments haven't worked.

  Recruiting Phase 2 Institute of Hematology & Blood Diseases Hospital, China · Tianjin, Tianjin Municipality and 1 other locations · NCT06716658

• Tofacitinib cream for treating early-stage Cutaneous T-cell Lymphoma

  This study is testing if a new cream can help people with early-stage Cutaneous T-cell Lymphoma feel better and improve their skin after 12 weeks of treatment.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT06698822

• Systemic treatments for cutaneous T‑cell lymphoma

  This project looks at how different systemic treatments are used in adults with cutaneous T‑cell lymphoma to see which approaches are linked to longer disease control in routine care.

  Recruiting at 9 sites Fondazione Italiana Linfomi - ETS · Ancona and 17 other locations · NCT06588868

• Molecular subtyping for treating cutaneous T-cell lymphoma

  This study is testing if personalized treatment plans based on specific molecular types can help people with cutaneous T-cell lymphoma feel better and live longer.

  Recruiting at 3 sites Peking University First Hospital · Beijing, Beijing Municipality and 2 other locations · NCT06436677

• Improving detection of tumor cells in cutaneous T-cell lymphoma

  This study is testing a new way to find and count tumor cells in the blood of patients with cutaneous T-cell lymphoma to help improve diagnosis and treatment monitoring.

  Recruiting Instituto de Investigación Biomédica de Salamanca · Salamanca · NCT06382844

• Combining pembrolizumab and mogamulizumab for advanced cutaneous T-cell lymphomas

  This study is testing if combining two drugs, pembrolizumab and mogamulizumab, can help people with advanced cutaneous T-cell lymphomas that haven't responded to other treatments.

  Recruiting Phase 2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT05956041

• Using photopheresis to treat early-stage Mycosis Fungoides

  This study is testing if a light-based treatment called photopheresis can help people with early-stage Mycosis Fungoides, a type of skin lymphoma, feel better.

  Recruiting Phase 2 Columbia University · New York, New York · NCT05680558

• Understanding how extracorporeal photochemotherapy causes cell death

  This study is trying to understand how a treatment called extracorporeal photochemotherapy helps patients with skin lymphomas and graft-versus-host disease by looking at how it causes certain cells to die.

  Recruiting Centre Hospitalier Universitaire de Besancon · Besançon · NCT05333367

• Combining bexarotene with radiotherapy for treating mycosis fungoides

  This study is testing if combining a medication called bexarotene with a type of radiation therapy can help people with mycosis fungoides, a skin cancer, feel better and improve their treatment results.

  Recruiting at 3 sites Phase 1 Memorial Sloan Kettering Cancer Center · Commack, New York and 2 other locations · NCT05296304

• Testing a new treatment for relapsed T-cell non-Hodgkin lymphoma

  This study is testing a new treatment called ST-001 to see if it can help people with relapsed T-cell non-Hodgkin lymphoma feel better and have fewer side effects.

  Recruiting at 10 sites Phase 1 SciTech Development, Inc. · Scottsdale, Arizona and 9 other locations · NCT04234048

• Testing a microdevice for drug screening in skin lesions of T-cell lymphoma

  This study is testing a small device that delivers cancer drugs directly into skin lesions to see if it helps people with cutaneous T-cell lymphoma or peripheral T-cell lymphoma.

  Recruiting Dana-Farber Cancer Institute · Boston, Massachusetts · NCT04045470

• Evaluating safety in patients with leukemia or lymphoma treated with mogamulizumab after stem cell transplantation

  This study is trying to see how safe the drug mogamulizumab is for people with certain types of leukemia or lymphoma after they have a stem cell transplant.

  Recruiting Kyowa Kirin Co., Ltd. · Milwaukee, Wisconsin · NCT04014374

• Exploring the microbiome in patients with cutaneous T cell lymphoma

  This study looks at the gut bacteria of people with cutaneous T cell lymphoma to see how it compares to healthy individuals and if it can help us understand the disease better.

  Recruiting Northwestern University · Chicago, Illinois · NCT03932279

• Collection of blood, urine, and tissue samples for research on skin conditions

  This study is collecting blood, urine, and tissue samples from people with skin conditions like cutaneous T-cell lymphoma, eczema, and atopic dermatitis to help improve treatments in the future.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT00177268

NIH-funded research (12)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• IL-15 and skin-homing CTCL: a targeted approach to curb skin lesions

  This grant studies how the inflammatory signal IL-15 drives CTCL T cells to settle in the skin and how blocking this pathway might help patients with this skin-limited leukemia.

  NIH research Thomas Jefferson University · Philadelphia, United States · NIH-11370320

• Staphylococcus aureus and CTCL: How skin bacteria may drive a blood cancer

  A doctor-scientist team is studying how certain strains of Staphylococcus aureus on the skin might influence the development and progression of cutaneous T-cell lymphoma (CTCL) in patients.

  NIH research New York University School of Medicine · New York, United States · NIH-11326309

• Understanding how IL-15 affects T-cell lymphoma in the skin

  This research explores how a specific signal, called IL-15, helps T-cell lymphoma cells move to and grow in the skin, aiming to find new ways to help patients with this condition.

  NIH research Thomas Jefferson University · Philadelphia, United States · NIH-11138570

• New antibody treatment for Non-Hodgkin Lymphoma and a type of skin lymphoma

  This project is testing a new antibody treatment, called BITR2101, for people with certain types of cancer, including Non-Hodgkin Lymphoma and Cutaneous T Cell Lymphoma.

  NIH research Boston Immune Technologies and Therapeutics, INC. · Winchester, United States · NIH-11131238

• Investigating how Staphylococcus aureus affects skin cancer development

  This study is looking at how a common skin bacteria called Staphylococcus aureus might affect the growth of Cutaneous T-cell lymphomas (CTCL), a type of skin cancer, by examining the bacteria found on patients' skin to find new ways to understand and treat the disease.

  NIH research New York University School of Medicine · New York, United States · NIH-11072057

• Understanding how gene regulation affects cutaneous T cell lymphoma

  This study is looking at how changes in DNA can affect a type of skin cancer called cutaneous T cell lymphoma, especially a severe form known as Sezary syndrome, to help find better ways to diagnose and treat it, and patients can help us learn more about how these changes might impact their treatment.

  NIH research VA San Diego Healthcare System · San Diego, United States · NIH-11030755

• Improving how skin samples are handled for better testing in skin lymphoma

  This study is looking at the best ways to handle skin biopsy samples from people with cutaneous T cell lymphoma to make sure the tests for their T cell genes are accurate, helping doctors diagnose and monitor treatment more effectively.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-10977523

• New treatment targeting cancer cells and their supportive environment in Non-Hodgkin Lymphoma.

  This study is testing a new treatment called BITR2101 that targets a specific part of cancer cells to help stop the growth of Non-Hodgkin Lymphoma, especially for those with Cutaneous T Cell Lymphoma, and it may be used on its own or with other therapies to improve patient outcomes.

  NIH research Boston Immune Technologies and Therapeutics, INC. · Winchester, United States · NIH-10911718

• Investigating how IL-15 affects skin cancer progression in patients with Cutaneous T-cell Lymphoma.

  This study is looking at how a protein called IL-15 affects the growth and movement of skin cancer cells in people with Cutaneous T-cell Lymphoma, using a special mouse model to find new ways to treat this condition.

  NIH research Thomas Jefferson University · Philadelphia, United States · NIH-10891650

• Improving sample handling for T cell lymphoma testing

  This study is looking to improve how skin biopsy samples are handled for people with cutaneous T cell lymphoma, so that the DNA and important markers stay safe and accurate, helping doctors make better diagnoses and treatment choices.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-10856922

• Targeted therapy for skin lymphoma using a new immunotoxin

  This study is testing a new treatment for cutaneous T-cell lymphoma (CTCL) that uses a special therapy to help your immune system fight the cancer more effectively, and it could be a great option for patients whose CTCL hasn't responded to other treatments.

  NIH research Rock Immune, INC. · Denver, United States · NIH-10850989

• Identifying genetic markers for skin lymphomas

  This study is looking at skin cancers called cutaneous T-cell lymphomas to find genetic clues that can help doctors diagnose and treat these conditions earlier and more effectively, especially for patients with specific types like mycosis fungoides and Sezary syndrome.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-10812990

Related topics

Quick answers

How many Cutaneous T Cell Lymphoma clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (12 trials), China (2 trials), France (1 trial), Spain (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 5, Phase 1: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →