Improving detection of tumor cells in cutaneous T-cell lymphoma
Official title: Design, Development, and Validation of Novel "Next Generation Flow" Approaches for Rapid, Specific, Sensitive, and Reproducible Detection of Tumor Cells in Cutaneous T-cell Lymphoma.
Run by Instituto de Investigación Biomédica de Salamanca · NCT06382844 · Data updated 2026-11-12
This study is testing a new way to find and count tumor cells in the blood of patients with cutaneous T-cell lymphoma to help improve diagnosis and treatment monitoring.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Instituto de Investigación Biomédica de Salamanca Academic / other |
| Locations | 1 site (Salamanca) |
| Status | Recruiting |
| Started | January 1, 2024 |
| Main results expected | September 30, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | May 1, 2025 |
| Trial ID | NCT06382844 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old diagnosed with cutaneous T-cell lymphoma.
✕Probably not a fit
Patients under 18 years old or those who do not consent to participate will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project focuses on identifying and quantifying circulating tumor cells in patients with cutaneous T-cell lymphoma, specifically mycosis fungoides and Sézary syndrome. The study aims to develop standardized flow-cytometry techniques to enhance the accuracy and reliability of tumor cell detection in clinical settings. By designing an optimal combination of markers for spectral flow-cytometry, the researchers will assess the specificity and sensitivity of this new approach using blood samples from patients. This could lead to better diagnosis and treatment monitoring for individuals with these rare and aggressive skin lymphomas.
Why it matters
Potential benefit: If successful, this study could lead to more accurate diagnoses and improved treatment outcomes for patients with cutaneous T-cell lymphoma.
How similar studies have gone: Other studies have shown promise in improving detection methods for tumor cells, but this specific approach using next-generation flow cytometry is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with cutaneous T-cell lymphoma * Over 18 years old * Sign the informed consent Exclusion Criteria: * Under 18 years old * Do not sign the informed consent
Where it's running
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Instituto de Investigación Biomédica de Salamanca (IBSAL)
Salamanca, Spain Recruiting
Study contacts
- Principal investigator: Julia M Almeida Parra, Prof. — Instituto de Investigación Biomédica de Salamanca
- Study coordinator: Julia M Almeida Parra, Prof.
- Email: jalmeida@usal.es
- Phone: +34 923 29 45 00
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.