Improving detection of tumor cells in cutaneous T-cell lymphoma
Design, Development, and Validation of Novel "Next Generation Flow" Approaches for Rapid, Specific, Sensitive, and Reproducible Detection of Tumor Cells in Cutaneous T-cell Lymphoma.
This study is testing a new way to find and count tumor cells in the blood of patients with cutaneous T-cell lymphoma to help improve diagnosis and treatment monitoring.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Instituto de Investigación Biomédica de Salamanca Academic / other |
| Locations | 1 site (Salamanca) |
| Trial ID | NCT06382844 on ClinicalTrials.gov |
What this trial studies
This project focuses on identifying and quantifying circulating tumor cells in patients with cutaneous T-cell lymphoma, specifically mycosis fungoides and Sézary syndrome. The study aims to develop standardized flow-cytometry techniques to enhance the accuracy and reliability of tumor cell detection in clinical settings. By designing an optimal combination of markers for spectral flow-cytometry, the researchers will assess the specificity and sensitivity of this new approach using blood samples from patients. This could lead to better diagnosis and treatment monitoring for individuals with these rare and aggressive skin lymphomas.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old diagnosed with cutaneous T-cell lymphoma.
Not a fit: Patients under 18 years old or those who do not consent to participate will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate diagnoses and improved treatment outcomes for patients with cutaneous T-cell lymphoma.
How similar studies have performed: Other studies have shown promise in improving detection methods for tumor cells, but this specific approach using next-generation flow cytometry is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with cutaneous T-cell lymphoma * Over 18 years old * Sign the informed consent Exclusion Criteria: * Under 18 years old * Do not sign the informed consent
Where this trial is running
Salamanca
- Instituto de Investigación Biomédica de Salamanca (IBSAL) — Salamanca, Spain (Recruiting)
Study contacts
- Principal investigator: Julia M Almeida Parra, Prof. — Instituto de Investigación Biomédica de Salamanca
- Study coordinator: Julia M Almeida Parra, Prof.
- Email: jalmeida@usal.es
- Phone: +34 923 29 45 00
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.